A5033282728- Multiple Myeloma Research and Treatments
- SARS-CoV-2 and COVID-19 Research
- Peptidase Inhibition and Analysis
- Chronic Lymphocytic Leukemia Research
- Protein Degradation and Inhibitors
- Amyloidosis: Diagnosis, Treatment, Outcomes
- COVID-19 Clinical Research Studies
- Bone health and treatments
- Cancer Treatment and Pharmacology
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Chronic Myeloid Leukemia Treatments
- Lymphoma Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Mechanisms and Therapy
- Long-Term Effects of COVID-19
- Cholangiocarcinoma and Gallbladder Cancer Studies
- HIV/AIDS drug development and treatment
- Lung Cancer Research Studies
- Cancer Immunotherapy and Biomarkers
- Neuroendocrine Tumor Research Advances
- Immunotherapy and Immune Responses
- Heparin-Induced Thrombocytopenia and Thrombosis
- Chemokine receptors and signaling
- Cancer Risks and Factors
- Circular RNAs in diseases
National and Kapodistrian University of Athens
2016-2025
Alexandra Hospital
2017-2025
Massachusetts General Hospital
2023
Boston Children's Hospital
2023
Harvard University
2023
Mayo Clinic
2023
Imperial College Healthcare NHS Trust
2023
St Mary's Hospital
2023
Imperial College London
2023
Institut Gustave Roussy
2023
Abstract Recent data suggest a suboptimal antibody response to COVID-19 vaccination in patients with hematological malignancies. Neutralizing antibodies (NAbs) against SARS-CoV-2 were evaluated 276 plasma cell neoplasms after either the BNT162b2 or AZD1222 vaccine, on days 1 (before first vaccine shot), 22, and 50. Patients MM ( n = 213), SMM 38), MGUS 25) 226 healthy controls enrolled study (NCT04743388). Vaccination two doses of one dose leads lower production NAbs compared both day 22 50...
Abstract Immune checkpoint inhibitors (ICIs) exhibit remarkable antitumor activity and immune-related cardiotoxicity of unknown pathomechanism. The aim the study was to investigate ICI class-dependent in vitro pembrolizumab’s (Pem’s) vivo, seeking for translational prevention means. Cytotoxicity investigated primary cardiomyocytes splenocytes, incubated with ipilimumab, Pem avelumab. Pem’s cross-reactivity assessed by circular dichroism (CD) on biotechnologically produced human murine PD-1...