- Sarcoma Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Photodynamic Therapy Research Studies
- Vasculitis and related conditions
- Tumors and Oncological Cases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cancer, Lipids, and Metabolism
- Winter Sports Injuries and Performance
- Porphyrin and Phthalocyanine Chemistry
- Advanced X-ray and CT Imaging
- Gastrointestinal Tumor Research and Treatment
- Glioma Diagnosis and Treatment
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Vascular anomalies and interventions
- Intestinal Malrotation and Obstruction Disorders
- Renal Diseases and Glomerulopathies
- Hedgehog Signaling Pathway Studies
- Ear and Head Tumors
- Vascular Malformations and Hemangiomas
- Genetic and rare skin diseases.
- Soft tissue tumor case studies
- Cholesterol and Lipid Metabolism
- Cancer-related cognitive impairment studies
- Neurological and metabolic disorders
- Abdominal vascular conditions and treatments
Seoul National University Dental Hospital
2023
Inje University Haeundae Paik Hospital
2023
Korea Brain Research Institute
2022
Korea Institute of Toxicology
2022
Gyeongsang National University Hospital
2022
Kyungpook National University Hospital
2022
Inje University Sanggye Paik Hospital
2019-2020
Yeungnam University
2017
St. Jude Children's Research Hospital
2016
Asan Medical Center
2015
In chronic myelogenous leukemia, reciprocal translocation between chromosome 9 and 22 generates a chimeric protein, Bcr-Abl, that leads to hyperactivity of tyrosine kinase-linked signaling transduction. The therapeutic agent nilotinib inhibits Bcr-Abl/DDR1 can cross the blood-brain barrier, but its potential impact on neuroinflammatory responses cognitive function has not been studied in detail.The effects vitro vivo were assessed by combination RT-PCR, real-time PCR, western blotting,...
The purpose of this study was to evaluate the CT characteristics newly developed lung cancer on studies obtained during follow-up idiopathic interstitial pneumonia (IIP) before appearance identifiable tumors time detectable and thereafter.The sample included 66 cancers diagnosed in 63 patients with IIP (59 men, four women; median age, 64 years; range, 40-85 years) between October 1998 July 2012. Two radiologists independently reviewed 193 scans, determined earliest presence IIP, evaluated...
Targeted next-generation sequencing (NGS) is widely used for simultaneously detecting clinically informative genetic alterations in a single assay. Its application clinical settings requires the validation of NGS gene panels. In this study, we aimed to validate targeted hybridization capture-based DNA panel (ONCOaccuPanel) using Illumina MiSeq platform. The allows simultaneous detection single-nucleotide variants (SNVs), insertions, deletions, and copy number changes 323 genes fusions 17...
Objective: The objective of this study is to investigate the effect intracellular photosensitizer distribution on tumor cell death after photodynamic therapy (PDT). Background Data: accumulates in tissue during PDT, and generates reactive oxygen species (ROS), resulting death. Materials Methods: This was carried out elucidate effects PDT a KB oral cancer line using hematoporphyrin with irradiation at 635 nm 5 mW/cm2. After irradiation, MTT reduction method, agarose gel electrophoresis, flow...
A 43-year-old female presented with persistent headache and dizziness which had first occurred two years earlier. The physical neurological findings at admission were unremarkable, though plain radiography revealed the presence of a dense calcified mass in left frontal area, CT showed that homogeneous high-density nodule was attached to inner surface skull. hard bony found excised during surgery shown histopathologic examination be subdural osteoma. We describe clinicopathologic this entity...
Regulation of lipogenesis by pathophysiological factors in the liver and skeletal muscle is well understood; however, regulation kidney still unclear. To elucidate nutritional lipogenic kidney, we measured renal expression transcriptional enzymes during fasting refeeding chow-fed high-fat-fed mice. We also examined regulatory effect X receptor (LXR) on factors. The gene sterol element-binding protein (SREBP)-1c fatty acid synthase (FAS) was reduced for 48 h restored refeeding, whereas mRNA...
Journal Article Multiple malignancies in a patient with limited granulomatosis polyangiitis without immunosuppressive therapy Get access Yun-Hong Cheon, Cheon Department of Internal medicine and Institute Health Science, Gyeongsang National University School Medicine, Jinju, South Korea Search for other works by this author on: Oxford Academic Google Scholar Min-Gyo Kim, Kim Ji-Eun Radiology, Chang Yoon Ha, Ha Sang-Il Lee, Lee Hyun-Ok Correspondence to: Medicine 79 Gangnam-ro, Jinju 660-702,...
The malignant transformation of Warthin's tumor in the parotid gland is extremely rare. In addition, among various types change tumor, squamous cell carcinoma rarest one. pathogenesis this rare disease entity uncertain till now. Also most effective treatment and long-term prognosis are not yet clear. Up to present, there a few reports that only described pathologic clinical features tumor. However, no report about imaging findings We case arising from gland.
Developmental venous anomaly (DVA), which is also called angioma, the most common cerebral vascular malformation (1, 2). DVA exhibits radially arranged, dilated veins (so-called caput medusae) that drain into an enlarged transcortical or a subependymal collecting vein (3). usually asymptomatic and it’s often incidentally found on contrast-enhanced (CE) CT MR imaging. Recent investigations have reported parenchymal signal abnormality T2/FLAIR imaging could be INTRODUCTION �Received; May 15,...
Background and Objectives: This study aimed to evaluate the utility accuracy of dual-energy automatic plaque removal (DE-APR) in patients with symptomatic peripheral arterial disease (PAD) using digital subtraction angiography (DSA) as reference standard. Materials Methods: We retrospectively analyzed 100 PAD who underwent DE computed tomography (DE-CTA) DSA lower extremities. DE-CTA was used generate APR subtracted images. In three main segments (aorto-iliac segment, femoro-popliteal...
Primary breast carcinoma with neuroendocrine features is an extremely rare and underrecognized subtype of the carcinoma.And up to present, its biologic behavior, most effective treatment, prognosis are not well recognized.To diagnose this entity, special tumor stains markers required, which routinely used.The imaging primary (BCNF) have been accurately described due extreme rarity type.We report in a case BCNF, findings different from typical invasive carcinoma.
<b>Introduction:</b> Pulmonary hypertension (PH) can be a risk factor for the disease severity and affect prognosis of patients with bronchiectasis. <b>Aims:</b> To evaluate association between PH hospital admission rates in <b>Methods:</b> We performed retrospective analysis 641 diagnosed bronchiectasis at National Medical Center, Korea, from November 2012 to October 2022. HRCT echocardiographic assessment were used PH. Patients divided into two groups according admission. Logistic...