About
Contact & Profiles
A5084306036
Research Areas
- Neuroscience and Neuropharmacology Research
- Congenital heart defects research
- ATP Synthase and ATPases Research
- Neurogenesis and neuroplasticity mechanisms
- Genetics and Neurodevelopmental Disorders
- Autism Spectrum Disorder Research
- Epigenetics and DNA Methylation
- Receptor Mechanisms and Signaling
- Retinal Development and Disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological disorders and treatments
University of California, Santa Cruz
2016-2021
10.1016/j.neuron.2018.09.027
article
EN
publisher-specific-oa
Neuron
2018-10-11
Exome sequencing studies have identified multiple genes harboring de novo loss-of-function (LoF) variants in individuals with autism spectrum disorders (ASD), including TBR1 , a master regulator of cortical development. We performed ChIP-seq for during mouse neurogenesis and show that TBR1-bound regions are enriched adjacent to ASD genes. were also among differentially expressed Tbr1 knockouts, which together the data, suggests direct transcriptional regulation. Of nine examined, seven...
10.1101/gr.203612.115
article
EN
cc-by-nc
Genome Research
2016-06-20
10.1016/j.celrep.2021.109269
article
EN
Cell Reports
2021-06-01
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