- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Intestinal and Peritoneal Adhesions
- Helicobacter pylori-related gastroenterology studies
- Pancreatic and Hepatic Oncology Research
- Hernia repair and management
- Gastrointestinal disorders and treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
- Ion Channels and Receptors
- Liver Disease Diagnosis and Treatment
- Lung Cancer Research Studies
- Gastric Cancer Management and Outcomes
- Cancer, Lipids, and Metabolism
- Reconstructive Surgery and Microvascular Techniques
- Liver physiology and pathology
- Hemostasis and retained surgical items
- Mercury impact and mitigation studies
- Intraperitoneal and Appendiceal Malignancies
- Hepatitis B Virus Studies
- Cancer Mechanisms and Therapy
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Cell death mechanisms and regulation
- Metastasis and carcinoma case studies
- Cardiac, Anesthesia and Surgical Outcomes
- Genetic and Kidney Cyst Diseases
Kaohsiung Veterans General Hospital
2000-2022
National Yang Ming Chiao Tung University
1998-2017
National Yang Ming University Hospital
2017
National Taipei University
2003-2012
Background: To evaluate hyperthermic intraperitoneal chemotherapy (HIPEC) as an adjuvant in advanced gastric cancer (AGC) patients with serosal invasion. Methods: Patients who received radical surgery and palliative between January 2002 December 2010 were retrospectively examined. divided into two groups, namely, one group that underwent another HIPEC. All HIPEC had suspected invasion on abdominal computed tomography or by the surgeon's assessment during operation. Results: The prophylactic...
// Wei-Chi Sun 1, 2, * , I-Shu Chen 3, Huei-Lung Liang 4 Cheng-Chung Tsai 3 Yu-Chia Being-Whey Wang Huey-Shyan Lin 5 Hoi-Hung Chan 2 Ping-I Hsu Wei-Lun and Jin-Shiung Cheng 1 Division of Gastroenterology Hepatology, Department Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan Shool National Yang-Ming University, Taipei, Surgery, Radiology, School Nursing, Fooying These authors contributed equally to this work Correspondence to: Tsai, email: tsaiwl@yahoo.com.tw...
To assess the risk factors that influence mortality from perforated peptic ulcer.Retrospective study.General hospital, Taiwan.179 patients who had their ulcers operated on and minimum follow-up of one year.Mortality.The overall was 15% (26/179). Of 26 died, cause death uncontrolled systemic infection in 21 (81%), hypovolaemic shock 2, fatal arrhythmia heart failure 1 each. 15 died sepsis did not have fulminant abdominal sepsis. Most deaths occurred early after operation, (range 1-96 days)....
The aim of this study was to evaluate the recurrence pattern after skin-sparing mastectomy (SSM) and immediate breast reconstruction (IBR) using transverse rectus abdominis musculocutaneous (TRAM) flap in patients with invasive cancer.From 1995 2010, cancer who underwent SSM followed by IBR TRAM were retrospectively reviewed. first event recorded.We identified 249 consecutive cancer, two-thirds whom (67.1%) diagnosed stage II or III disease. During a median follow-up period 53 months, three...
Thimerosal is a mercury-containing preservative in some vaccines. The effect of thimerosal on human gastric cancer cells unknown. This study shows that cultured (SCM1), reduced cell viability concentration- and time-dependent manner. caused apoptosis as assessed by propidium iodide–stained caspase-3 activation. Although immunoblotting data revealed could activate the phosphorylation extracellular signal–regulated kinase, c-Jun NH2-terminal protein p38 mitogen-activated kinase (p38 MAPK),...
Background: The significance of lymph node involvement regarding the prognosis primary duodenal adenocarcinoma remains controversial. This study aims to evaluate prognostic accuracy nodal metastasis using seventh edition American Joint Committee on Cancer staging system in patients with adenocarcinoma. Methods: Between 1993 and 2010, 36 who had undergone surgical resection for at Kaohsiung Veterans General Hospital were retrospectively reviewed. Results: median disease-free survival all was...
1. It has been shown that the antidepressant desipramine is able to induce increases in [Ca(2+)](i) and cell death MG63 human osteosacroma cells, but whether apoptosis involved unclear. In present study, effect of on underlying mechanisms were explored. was demonstrated induced a concentration- time-dependent manner. 2. Cells treated with 100-800 mmol/L showed typical apoptotic features, including an increase sub-diploid nuclei activation caspase 3, indicating these cells underwent...
Nodular regenerative hyperplasia (NRH), characterized by diffuse hepatic micronodular transformation in groups without fibrous septa between the nodules, is a rare benign liver lesion that has many synonyms previous literature. Pathologic evaluation mainstay of accurate diagnosis. Treatment focused on its underlying conditions and complications portal hypertension. A 39-year-old man visited our hospital due to right upper quadrant pain palpable mass. Magnetic resonance examination revealed...
Angiosarcoma is a rare soft-tissue neoplasm that occurs most often in the skin and subcutaneous tissues but very rarely gastrointestinal tract. We report case of primary intestinal angiosarcoma with severe bleeding. This patient was referred to our institute for shock tarry-bloody stool anemia. Panendoscopy revealed multiple duodenal polypoid tumors, initial biopsy specimen showed poorly differentiated adenocarcinoma. The tumors were treated pancreaticoduodenectomy, died 2 weeks after...
Patients with liver metastasis from breast cancer (LMBC) are usually offered systemic therapy. However, for those progressive disease and limited extra-hepatic conditions, local management becomes an option. Herein we present our experience hepatic arterial infusion chemotherapy (HAIC).From 1999 to 2018, 42 patients LMBC, who had after therapy, were treated HAIC. A catheter was placed angiographically into the artery remained there 5 consecutive days. One cycle of consisted mitoxantrone,...
Vacuum-assisted breast biopsy (VABB) for benign tumor excision is a developing trend in surgery. The most common complication of VABB hematoma. We assessed the efficiency thrombin-gelatin matrix (TGM) hemostasis after VABB.From December 2013 to June 2017, 147 patients with tumors > 2 cm size were treated 7-gauge ultrasound-guided EnCor EnSpire® system. After VABB, TGM was applied using an iron-tube device. injection, brief external compression 15 min and postoperative bandage approximately...
Background: Intestinal obstruction is one of the most common surgical emergencies. The aim this study was to identify important management information from evaluation patients with intestinal who had undergone previous laparotomy for non-malignancy. Methods: Data 176 non-malignancy, and were operated on obstruction, collected analyzed retrospectively. Results: Gastroduodenal operations, appendectomy, obstetric/gynecologic procedures 3 abdominal surgeries. More than half all bowel...
The effects of econazole, an antifungal drug applied for treatment keratitis and mycotic corneal ulcer, on cytosolic-free Ca2+ concentrations ([Ca2+]i) viability cells was examined by using SIRC rabbit epithelial as model. [Ca2+]i cell were measured the fluorescent dyes fura-2 WST-1, respectively. Econazole at ≥ 1 µM increased in a concentration-dependent manner. signal reduced partly removing extracellular Ca2+. econazole-induced Ca(2+) influx insensitive to L-type channel blockers protein...