A5101861147- Cancer-related molecular mechanisms research
- Bladder and Urothelial Cancer Treatments
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Urinary and Genital Oncology Studies
- Renal cell carcinoma treatment
- Cancer-related gene regulation
- Healthcare and Venom Research
- Liver Disease Diagnosis and Treatment
- Cancer Research and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Urological Disorders and Treatments
- Inflammatory Biomarkers in Disease Prognosis
- Epigenetics and DNA Methylation
- Ubiquitin and proteasome pathways
- Hepatitis B Virus Studies
- Medical Research and Treatments
- Ferroptosis and cancer prognosis
- Microtubule and mitosis dynamics
- Genetic and Kidney Cyst Diseases
- Traditional Chinese Medicine Analysis
- Enhanced Recovery After Surgery
- Cancer, Lipids, and Metabolism
- Renal and related cancers
- Advanced Optical Imaging Technologies
First Affiliated Hospital of Bengbu Medical College
2009-2025
Tongji Hospital
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2023
Huazhong University of Science and Technology
2023
Shandong Maternal and Child Health Hospital
2020
Bengbu Medical College
2008-2018
Operation PAR
2011
Xinhui People's Hospital
2009
Tianjin Conservatory of Music
2002
MicroRNA (miRNA or miR)‑485 is a functional miRNA which has received much attention in recent years. However, little known about the expression of miR‑485 role it plays bladder cancer [namely metastasis and epithelial‑mesenchymal transition (EMT)]. Thus, present study, we aimed to detect human tissues cell lines, examine effects miR‑485‑5p on EMT. We found that was downregulated different lines compared with normal as demonstrated by reverse transcription‑quantitative polymerase chain...
MicroRNA-100 (miR-100) has been demonstrated to be downregulated in bladder cancer tissues, and enforced expression of this miRNA may inhibit cell growth colony formation human 5637 cells vitro. However, the clinical significance miR-100 not yet elucidated. Thus, aim study was investigate diagnostic prognostic values disease.Expression levels 126 pairs adjacent normal tissues were detected by TaqMan real-time quantitative RT-PCR assay. In order determine its value, overall survival (OS)...
To study the clinical effects of a disposable circumcision device in treatment male patients different ages with either phimosis or excess foreskin.One thousand two hundred between age 5 and 95 years underwent using this procedure 2-year period October 2005 September 2007. Of these cases, 904 had foreskin 296 were cases phimosis.In 96.33% incision healed, leaving minimal amount inner no scarring producing good cosmetic results. There incidents dislocation damage to frenulum. The average...
ObjectiveThis study aims to investigate the potential prognostic value of albumin-bilirubin (ALBI) score in breast cancer patients with liver metastasis after surgery.MethodsThis was a retrospective 178 surgery. ALBI calculated by following formula: (log10 bilirubin × 0.66) − (albumin 0.085). The optimal cutoff assessed X-tile. clinical influence on survival outcomes using Kaplan-Meier method, Log-rank test, Cox proportional hazards regression model. calibration curves, decision curve...
To investigate the role of centromere protein U (CENPU) in human bladder cancer (BCa), CENPU gene expression was evaluated BCa tissues. We used real-time quantitative PCR (qPCR) and found that tissues higher compared to observed cancer-adjacent normal High be strongly correlated with tumor size TNM stage. Kaplan-Meier survival analysis indicated high levels were associated reduced survival. a lentivirus silence endogenous T24 cell line. knockdown confirmed by qPCR. Cellomic imaging BrdU...
BRAF-activated long non-coding RNA (BANCR) has been associated with various types of cancer. Nevertheless, the role BANCR in clear cell renal carcinoma (ccRCC) is still not fully understood. This study aims to investigate relationship between ccRCC and BANCR. Expression TCGA cancer data sets was analyzed. The expression pattern Immortalized normal human proximal tubule epithelial line HK-2 lines (ACHN, CAKI-1, A498 786-O) detected by real-time quantitative RT-PCR (qRT-PCR). tissues adjacent...
Long noncoding RNAs (lncRNAs) act as competing endogenous (ceRNAs) in the regulation of gene expression various physiological and pathological processes. The present study aimed to explore lncRNA‑miRNA‑mRNA interactions clear cell renal carcinoma (ccRCC) using comprehensive bioinformatics analysis. RNA‑seq data were downloaded from TCGA Data Portal, differentially expressed lncRNAs (DElncRs), miRNAs (DEmiRs), mRNAs (DEGs) between tumoral control samples identified edgeR package. correlations...
This study aimed to determine the potential utility of plasma fibrinogen as a prognostic factor in patients with bladder cancer (BCa) after radical cystectomy (RC).Patients BCa who underwent RC from 2014 2019 were analyzed retrospectively. The indexes coagulation and fibrinolysis system factors collected. Kaplan-Meier survival curves used calculate overall (OS) disease-free (DFS). value was by using Cox regression model, nomogram based on generated R software.Among 145 patients, optimal...
Abstract Objective The aim of the present work was to evaluate folate-receptor 1 ( FOLR1 ) expression in cervical squamous cell carcinoma and its clinical significance. Methods mRNA level detected cancer genome atlas (TCGA) database for multiple carcinomas. relative between tumor tissue normal cervix patients compared by online data analysis tool GEPIA. overall survival (OS) progression free (PFS) high low groups were log-rank test. Thirty one 20 healthy controls included tested serum...
Objective To evaluate the efficacy and safety of PA-MSHA injection for preventing recurrence non muscle-invasive bladder cancer. Methods 137 patients with recurrent cancer after TURBT were assigned into two groups. Treatment group (n=68) received instillation 10 ml 1 week operation 12 months, control (n=69) 20 mg Hydroxycamptothecin. The tumor rates side effects treatment evaluated. Results The 16.2% (11/68) 30.4% (21/69) respectively (P<0.05). There no statistically significant...