A5043916325- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Urological Disorders and Treatments
- Renal cell carcinoma treatment
- Blood Pressure and Hypertension Studies
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Renal and related cancers
- Hormonal Regulation and Hypertension
- Genital Health and Disease
- Testicular diseases and treatments
- Prostate Cancer Treatment and Research
- Circular RNAs in diseases
- Cancer, Hypoxia, and Metabolism
- Sperm and Testicular Function
- Adrenal and Paraganglionic Tumors
- Dialysis and Renal Disease Management
- Extracellular vesicles in disease
- Reproductive Biology and Fertility
- Urinary Bladder and Prostate Research
- Prostate Cancer Diagnosis and Treatment
- Sodium Intake and Health
- Liver Diseases and Immunity
- Cancer-related gene regulation
- Bioactive Compounds and Antitumor Agents
Henan Provincial People's Hospital
2015-2025
Zhengzhou University
2014-2024
Henan University
2019-2022
John Wiley & Sons (United States)
2018
Hudson Institute
2018
Zhengzhou People's Hospital
2014
Non-muscle invasive bladder cancer (NMIBC) is a major type of with high incidence worldwide, resulting in great disease burden. Treatment and surveillance are the most important part NIMBC management. In 2018, we issued "Treatment for non-muscle-invasive China: an evidence-based clinical practice guideline". Since then, various studies on treatment NMIBC have been published. There need to incorporate these materials also take into account relatively limited medical resources primary...
Macrophage polarization plays an important role in tumor microenvironment, which regulated the prognosis of prostate cancer. However, potential it is still need further identification.The M1 Macrophages were inducted using 100 ng/mL LPS and IFN-γ, 20 IL-4. TAMs obtained by culturing monocytes for 7 days RPMI 1640 10% FBS with 50% conditioned medium from PC-3 cells real-time PCR was performed to determine expression miR-148a, CCAT1, PKCζ. Western blot used measure level The cytokine IL-10...
Abstract Benign prostatic hyperplasia (BPH) is highly prevalent among older men, impacting on their quality of life, sexual function, and genitourinary health, has become an important global burden disease. Transurethral plasmakinetic resection prostate (TUPKP) one the foremost surgical procedures for treatment BPH. It well established in clinical practice with good efficacy safety. In 2018, we issued guideline “2018 Standard Edition”. However much new direct evidence now emerged this may...
Abstract Objectives Microvesicles (MVs) derived from human Wharton’s jelly mesenchymal stem cells (MSC-MVs) were demonstrated to ameliorate acute lung injury (ALI). We have previously found that MSC-MV-transferred hepatocyte growth factor was partly involved in their therapeutic effects. Since MSC-MVs also contained a substantial quantity of miR-100, which plays an important role cancer and injury, we speculated miR-100 might similarly account for part the effects MSC-MVs. Methods MSCs...
To assess the ability of preoperative plasma fibrinogen and D-dimer as biomarkers to predict survival outcomes in patients with non-muscle-invasive bladder cancer (NMIBC).A total 206 NMIBC receiving transurethral resection tumor (TURBT) were assessed our retrospective study. The cutoff values determined using receiver operating characteristic curve analysis. Cox regression analyses adopted influence these two parameters on recurrence-free (RFS) progression-free (PFS).The 3.56 g/L 0.48 μg/mL,...
Microvesicles (MVs) derived from human umbilical cord mesenchymal stem cells (hUC-MSCs-MVs) and miR-21 were demonstrated to ameliorate renal ischemia-reperfusion injury (IRI). Since hUC-MSC-MVs contained a substantial quantity of miR-21, we speculated that might account for part the therapeutic effects hUC-MSCs-MVs. The tubule epithelial (HK-2) cultured under low oxygen (LO) condition mimic cellular IRI model. A rat model unilateral was established. co-culture HK-2 MSC-MVs utilized examine...
Osteoporosis (OP) characterizes a decrease in bone density and mass which leads to brittle fractures serious damages individuals. In recent years, various researches have proved that miRNAs act pivotally the onset of bone-related diseases. our research, we probed into impact miR-181a-5P on viability, differentiation, as well apoptosis human marrow mesenchymal stem cells (hBMSCs). Our study reported overexpressing miR-181a-5p considerably reduced cell growth, whereas inhibition showed...
99mTc-HYNIC-PSMA is a novel technetium-99m-labeled small-molecule inhibitor of prostate-specific membrane antigen (PSMA) for detection prostate cancer. The present study investigated the diagnostic yield Single photon emission computed tomography (SPECT)/CT in 147 patients with biochemically recurrent cancer after radical prostatectomy.147 biochemical relapse prostatectomy were finally eligible this retrospective analysis. median (PSA) level was 8.26 ng/mL (range, 0.22-187.40 ng/mL). Of...
Objective: To compare the efficacy and safety of hyperthermic intravesical chemotherapy (HIVEC) chemotherapy(IVEC) in patients with intermediate high risk nonmuscle-invasive bladder cancer (NMIBC) after transurethral resection. Methods: We included 560 diagnosed primary or recurrent NMIBC between April 2009 December 2015 at 1of 6 tertiary centers. matched 364 cases divided them into 2 groups: HIVEC+IVEC group[chemohyperthermia (CHT) composed 3 consecutive sessions followed by instillation...
Abstract Background EAU guidelines strongly recommend kidney sparing surgery (KSS) as the primary treatment option for low-risk UTUC patients. While there are few reports involving KSS treated high-risk counterparts, especially ureteral resection. Objective To evaluate effectiveness and safety of segmental ureterectomy (SU) patients with carcinoma. Materials methods We included 20 from May 2017 to December 2021 who underwent in Henan Provincial People’s Hospital. The overall survival (OS)...
Objective: To compare the efficacy and safety of a novel thermochemotherapy scheme instillation pirarubicin (THP) without hyperthermia in patients with intermediate- high-risk nonmuscle-invasive bladder cancer (NMIBC).Materials methods: Between June 2012 December 2016, 300 urothelial carcinoma undergoing intravesical adjuvant therapy THP after transurethral resection tumors (TURBT) were enrolled study. These divided into CTHC group (thermochemotherapy composed three consecutive sessions...
Previous studies describing renal denervation (RDN) from the intima of artery for treatment resistant hypertension have reported variable efficacies, and RDN triggers intimal injury atherosclerosis. This study aimed to evaluate efficacy safety adventitia plus unilateral laparoscopic adrenalectomy treat patients with caused by aldosterone-producing adenoma (APA). A total 60 consecutive APA were enrolled in this study. Patients randomly assigned undergo (RDN group, n = 30) or alone (control...
The purpose of this study was to explore the neural mechanism in Chronic prostatitis/Chronic pelvic pain syndrome (CP/CPPS) using resting-state functional magnetic resonance imaging. imaging performed on 31 male CP/CPPS-patients and age education matched healthy controls a 3-T unit. A two-sample t-test adopted reveal regional homogeneity between patients controls. mean values alerted brain regions were correlated with clinical measurements by Pearson's correlation analyses. had significantly...
A 38-year-old man with a history of resistant hypertension for more than 10 years underwent laparoscopic-based perivascular unilateral renal sympathetic nerve denervation in 2012. After the operation, patient's blood pressure has been controllable while antihypertensive drug intake decreased over 6 years. Laparoscopic-based may be potentially feasible and effective option treating patients hypertension.
Abstract The aim of this study was to explore the long‐term clinical results Renal denervation (RDN) from adventitia renal artery plus unilateral laparoscopic adrenalectomy treat patients with resistant hypertension caused by aldosterone‐producing adenoma (APA). Sixty APA who were treated at Henan Provincial People's Hospital December 2016 March 2018 selected and randomly assigned undergo RDN (RDN group, n = 30) or alone (control 30). Office blood pressure (BP), antihypertensive medication...
To investigate the clinicopathological features of collecting duct carcinoma (CDC) and improve its diagnosis treatment.A retrospective analysis was performed with clinical data including follow-up results five patients CDC.A total 5 cases, 4 males 1 female, were included in this average age 54 years (range 42 to 65). Patients mainly suffered from lumbar pain, hematuria, abdominal mass low grade fever. Four underwent radical nephrectomy while another received palliative nephrectomy. Lymph...
Osteoporotic vertebral compression fractures (OVCFs) are acknowledged to be common fractures, especially in the elderly population. Minimally invasive percutaneous methods of treatment for these such as kyphoplasty (KP) and vertebroplasty (VP) have been valid effective tools decreasing clinical problems, which associated with more beneficial effects compared traditional open surgery or conservative treatment. Hence, we conducted current meta-analysis order gather updated evidence systematic...