Xiaofeng Zou

ORCID: 0000-0002-7472-4488
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About
Contact & Profiles
Research Areas
  • Minimally Invasive Surgical Techniques
  • Ubiquitin and proteasome pathways
  • Urinary Bladder and Prostate Research
  • Ureteral procedures and complications
  • Urological Disorders and Treatments
  • Kidney Stones and Urolithiasis Treatments
  • MicroRNA in disease regulation
  • RNA modifications and cancer
  • Pediatric Urology and Nephrology Studies
  • Bladder and Urothelial Cancer Treatments
  • Extracellular vesicles in disease
  • Cancer-related molecular mechanisms research
  • Cancer-related gene regulation
  • Ferroptosis and cancer prognosis
  • Epigenetics and DNA Methylation
  • Cancer-related Molecular Pathways
  • Abdominal Surgery and Complications
  • Hippo pathway signaling and YAP/TAZ
  • Urinary Tract Infections Management
  • Prostate Cancer Treatment and Research
  • Surgical Simulation and Training
  • Circular RNAs in diseases
  • Protein Degradation and Inhibitors
  • Urinary and Genital Oncology Studies
  • Thyroid and Parathyroid Surgery

First Affiliated Hospital of Gannan Medical University
2011-2025

Sun Yat-sen Memorial Hospital
2023-2025

Sun Yat-sen University
2023-2025

Zunyi Medical University
2022-2025

Gansu University of Traditional Chinese Medicine
2024

Gannan Medical University
2022-2024

Jiujiang First People's Hospital
2024

Ganzhou People's Hospital
2013-2016

University of Duisburg-Essen
2012

Qingdao Agricultural University
2011

Fork head box M1 (FoxM1) is a proliferation-associated transcription factor essential for cell cycle progression. Numerous studies have documented that FoxM1 has multiple functions in tumorigenesis and its elevated levels are frequently associated with cancer The present study was conducted to investigate the expression of prognostic significance clear renal carcinoma (ccRCC). Meanwhile, function human ccRCC further investigated culture models.Real-time quantitative PCR, western blot...

10.1186/1479-5876-10-200 article EN cc-by Journal of Translational Medicine 2012-09-24

Abstract Benign prostatic hyperplasia (BPH) is highly prevalent among older men, impacting on their quality of life, sexual function, and genitourinary health, has become an important global burden disease. Transurethral plasmakinetic resection prostate (TUPKP) one the foremost surgical procedures for treatment BPH. It well established in clinical practice with good efficacy safety. In 2018, we issued guideline “2018 Standard Edition”. However much new direct evidence now emerged this may...

10.1186/s40779-022-00371-6 article EN cc-by Military Medical Research 2022-04-01

Abstract The incidence of prostate cancer (PCa), the most prevalent malignancy, is currently at forefront. RNA modification a subfield booming field epigenetics. To date, more than 170 types modifications have been described, and N6-methyladenosine (m6A) abundant well-characterized internal mRNAs involved in various aspects progression. METTL3, first identified key methyltransferase, regulates human mRNA non-coding expression an m6A-dependent manner. This review elucidates biological...

10.1186/s12885-023-11741-1 article EN cc-by BMC Cancer 2024-01-02

Tetramethylpyrazine (TMP) has been confirmed to suppress inflammation in endometriosis (EMs). Herein, this study investigated whether and how TMP affected NLRP3 inflammasomes oxidative stress EMs. After establishment of an EMs rat model, rats were treated with different concentrations TMP. The size endometriotic lesions the latency frequency torsion recorded, followed by measurement relevant indicators (TNF-α, IL-6, IL-2, IL-10, MDA, SOD, GSH, CAT, ROS, NLRP3, ASC, GSDMD, caspase-1, Nrf2,...

10.1080/15476278.2025.2460261 article EN cc-by Organogenesis 2025-02-18

Objective: To explore the safety, effectiveness, and short-term outcomes of transoral robotic surgery (TORS) for supraglottic laryngeal cancer. Methods: A retrospective analysis was conducted on patients with cancer who underwent TORS at Sun Yat-sen Memorial Hospital University, Tongji Medical College Huazhong University Science Technology, Eye Ear Nose Throat Fudan First Affiliated China between January 2018 April 2024. Data operative time, intraoperative blood loss, postoperative hospital...

10.3760/cma.j.cn115330-20240807-00466 article EN PubMed 2025-03-20

Abstract Background Circular RNAs (circRNAs) are reported to be key regulators in the progression of human cancers. This work focuses on function and molecular mechanism circRNA-BNC2 (circ-BNC2) (also known as hsa_circ_0008732) ovarian cancer (OC). Methods Quantitative real-time polymerase chain reaction (qRT-PCR) was conducted detect circ-BNC2, microRNA-223-3p (miR-223-3p) F-box WD repeat domain containing 7 (FBXW7) mRNA expressions OC tissues cells. Besides, cell counting kit 8 (CCK-8),...

10.1186/s13048-022-01025-w article EN cc-by Journal of Ovarian Research 2022-08-14

To investigate the common etiologies, characteristics, and management of ureteric injury.A nationwide study was performed in 38 medical centers from Mar 2017 to 2019. The data patients with injury were retrospectively collected.Overall, 294 included this study. Ten cases (3.4%) due abdominal injuries, 284 (96.6%) iatrogenic including 48.6% urological procedures, 41.9% gynecological 6.3% general surgery, 3.2% other treatments. Most injuries (79.7%) caused by endourological procedures. Injury...

10.21037/tau-21-998 article EN Translational Andrology and Urology 2022-05-06

Abstract To present our experience with laparoscopic ureteroneocystostomy bladder flap (LUCBF) for treating benign ureteral stenosis and evaluate its feasibility efficacy. The clinical data of 27 patients who underwent LUCBF were retrospectively analyzed. After identification excision the segment, healthy stump was dissected incised longitudinally. A U-shaped or spiral harvested from anterolateral wall ureteroplasty. All successfully, including 14 combined psoas hitch technique, between 90...

10.1038/s41598-024-52497-3 article EN cc-by Scientific Reports 2024-01-23
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