A5062806492- Bone health and osteoporosis research
- Bone health and treatments
- Bone Metabolism and Diseases
- Vitamin D Research Studies
- Bone and Joint Diseases
- Musculoskeletal pain and rehabilitation
- Parathyroid Disorders and Treatments
- Hormonal and reproductive studies
- Orthopedic Infections and Treatments
- Spine and Intervertebral Disc Pathology
- Estrogen and related hormone effects
- Infectious Diseases and Tuberculosis
- Vitamin C and Antioxidants Research
- Hip and Femur Fractures
- Medical Imaging and Pathology Studies
- Lipoproteins and Cardiovascular Health
- Dermatological and Skeletal Disorders
- Nutrition and Health in Aging
- Sexual Differentiation and Disorders
- Multiple Myeloma Research and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Radiomics and Machine Learning in Medical Imaging
- Adrenal Hormones and Disorders
- Inflammatory Myopathies and Dermatomyositis
- Heterotopic Ossification and Related Conditions
Centre Hospitalier Universitaire d'Angers
2015-2024
Inserm
2006-2024
Nantes Université
2020-2024
Université d'Angers
2011-2021
Biomatériaux et Bioingénierie
2008-2021
Clinique Jules Verne
2018
Société Française de Rhumatologie
2011-2016
Université Nantes Angers Le Mans
2014
Centre Hospitalier Annecy Genevois
2010
Hôpital Larrey
2004
Background. The objective of this quasi-experimental study was to determine whether bolus vitamin D supplementation taken either regularly over the preceding year or after diagnosis COVID-19 effective in improving survival among hospitalized frail elderly patients. Methods. Seventy-seven patients consecutively for a geriatric unit were included. Intervention groups participants supplemented with (Group 1), and those 2). comparator group involved having received no supplements 3). Outcomes...
Some studies have indicated that the risk of fragility fractures in men increases as bone mineral levels decrease, but there is an overlap density (BMD) measurements between patients with or without fractures. Furthermore, it has been suggested biomechanical competence trabecular dependent not only on absolute amount present also microarchitecture. In study, 108 (mean age 52.1 years) lumbar osteopenia (T score < -2.5) were recruited to examine relationships BMD, architectural changes bone,...
Prolonged corticosteroid (CS) therapy induces osteoporosis and fractures. Osteoporosis is characterized at the histomorphometric level by reduced bone volume (BV/TV) disruption of three-dimensional (3D) trabecular architecture. Several stereological methods have been proposed to characterize these alterations: measurements thickness number, star volumes, interconnectivity index (ICI) marrow spaces, pattern factor (TBP(f)). These were computerized with a single program running on an image...
Abstract Morphometric analysis of 70 bone biopsies was done in parallel by μCT and histomorphometry. provided higher results for trabecular thickness separation because the 3D shape these anatomical objects. Introduction: Bone histomorphometry is used to explore various metabolic diseases. The technique on microscopic 2D sections, several methods have been proposed extrapolate measurements dimension. X-ray a recently developed imaging tool appreciate architecture. Recently use...
Randomized parallel group comparative trial with a 1-year follow-up period.To compare in population of patients chronic low back pain, the effectiveness functional restoration program (FRP), including intensive physical training and multidisciplinary approach, an outpatient active physiotherapy at follow-up.Controlled studies conducted United States Northern Europe showed benefit FRPs, especially on return to work. have compared these programs standard care. A previously reported study...
Osteoporosis is defined as a disease characterized by low bone mass and microarchitectural deterioration of trabecular leading to enhanced fragility. Various histomorphometric methods have been described measure architecture on histological sections. However, not all the are strictly equivalent some them appear able detect differences earlier in course disease. We compared 8 known characterize 154 male osteoporotic patients. Measurements were done transiliac biopsies: Trabecular number,...
Abstract Trabecular bone has been reported as having two‐dimensional (2‐D) fractal characteristics at the histological level, a finding correlated with biomechanical properties. However, several dimensions ( D ) are known and computational ways to obtain them vary considerably. This study compared three algorithms on same series of biopsies, Kolmogorov, Minkowski–Bouligand, mass‐radius dimensions. The relationships histomorphometric descriptors 2‐D trabecular architecture were investigated....
In chronic kidney disease and dialysis patients, vitamin D deficiency is associated with mortality. some observational studies, calcitriol analogue therapy was a better survival rate in hemodialysis (HD) patients. The aim of this study to determine the relationship between serum 25-hydroxyvitamin (25-OHD) levels alfacalcidol HD patients' outcomes.We measured baseline 25-OHD using cross-sectional analysis 648 prevalent patients from regional ARNOS French cohort. A 42-month applied according...