Ayhan Balkan

ORCID: 0000-0002-6475-9847
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • Animal Virus Infections Studies
  • Esophageal and GI Pathology
  • Pancreatitis Pathology and Treatment
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Viral gastroenteritis research and epidemiology
  • Systemic Lupus Erythematosus Research
  • Cancer, Lipids, and Metabolism
  • Hepatitis Viruses Studies and Epidemiology
  • Inflammatory Biomarkers in Disease Prognosis
  • Gallbladder and Bile Duct Disorders
  • Anesthesia and Sedative Agents
  • Cultural and Sociopolitical Studies
  • Ocular Diseases and Behçet’s Syndrome
  • Congenital Anomalies and Fetal Surgery
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Mycobacterium research and diagnosis
  • Abdominal Surgery and Complications
  • Pancreatic and Hepatic Oncology Research
  • Abdominal vascular conditions and treatments
  • Polyomavirus and related diseases
  • Linguistics and Cultural Studies
  • Celiac Disease Research and Management

Gaziantep University
2010-2025

Pulmonary Associates
2006-2008

Abstract Background Ulcerative colitis (UC) is a chronic disease with relapses and remissions that may also be associated extra-intestinal pathologies (1). Patients develop anemia due to or bloody diarrhea, which cause shortness of breath limitation in exercise capacity (2). The aim this study was compare UC patients healthy subjects determine the relationship between presence disease, activation status treatment pulmonary function obstructive sleep apnea syndrome (OSAS). Methods included 55...

10.1093/ecco-jcc/jjae190.0672 article EN Journal of Crohn s and Colitis 2025-01-01

The aim of the study is to evaluate analgesic efficiency perioperative magnesium sulphate infusion in patients undergoing laparoscopic cholecystectomy (LC).In a randomized, double-blind trial study, 83 were divided into two groups. Group MT received 50 mg/kg i.v. 100 ml 0.9% normal saline and T same volume isotonic during intraoperative period. cumulative post-operative tramadol consumption was measured assess effect using patient-controlled analgesia device. Pain intensities at rest while...

10.1111/j.1399-6576.2008.01816.x article EN Acta Anaesthesiologica Scandinavica 2008-10-17

Hepatocellular carcinoma is associated with several chronic inflammatory conditions. It increasingly understood that the inflammation may be part of carcinogenic process and prognostically important.To evaluate serum levels three markers in relation to survival HCC patients.We retrospectively examined CRP, albumin ESR, both singly combination, patient survival.Survival worsened increase CRP or ESR decrease levels. Combinations plus were an even greater range (3-fold), together significant...

10.1111/ijcp.13593 article EN International Journal of Clinical Practice 2020-06-25

Aim: With industrialization, there has been an increase in chronic diseases due to continuous change of nutrition. Tarhana is a traditional grain-based product fermented by lactic acid bacteria Turkish cuisine. This study aims evaluate possible effects tarhana on the impaired lipid profile parameters and serum glucose values male BALB/c mice fed high-fat diet. Materials Methods: Male were grouped into three different strain groups: control group (n=10), high fat diet (HFD) (n=10)...

10.30569/adiyamansaglik.1478460 article EN Adıyaman Üniversitesi Sağlık Bilimleri Dergisi 2024-08-30

Hepatocellular carcinoma (HCC) biomarkers are limited, as even the best studied, alpha-fetoprotein (AFP), is elevated in no more than 50% of HCC patients. The aim was to evaluate several serum liver function tests relation survival and tumor characteristics a large cohort Turkish patients.We retrospectively examined levels gamma glutamyl transpeptidase (GGT) patient survival.Kaplan-Meier analysis showed that only GGT albumin amongst tests, were significantly associated with survival....

10.15761/jts.1000446 article EN Journal of Translational Science 2021-01-01

Both unsedated transoral endoscopy (TOE) and sedated TOE have some drawbacks in clinical practice. Unsedated transnasal (TNE) has been suggested as an alternative to both methods. This study aimed determine the advantages of TNE patients who previously undergone conventional TOE.Patients had received last 12 months were scheduled for a second upper included. They randomized undergo either TOE, using standard endoscope, or TNE, ultrathin endoscope. Post-procedure, asked complete questionnaire...

10.15403/jgld-1275 article EN cc-by-nc-nd Journal of Gastrointestinal and Liver Diseases 2014-03-01

Fluctuations in hepatitis B virus (HBV) DNA and alanine transaminase (ALT) levels complicate assessment of the phases chronic (CHB) infection correct identification inactive HBV carrier state. In this study, we aimed to examine role HBsAg quantification (qHBsAg) evaluate its association with liver histopathology.Inactive carriers (IC) (n = 104) CHB patients 100) were enrolled study. Demographic characteristics evaluated; biochemical parameters serum qHBsAg studied, biopsy histopathology...

10.4103/1319-3767.182454 article EN cc-by-nc-sa Saudi Journal of Gastroenterology 2016-01-01

Abstract Extrahepatic cholangiocarcinoma (ECC) is an aggressive malignancy causing a lot of fatalities and comorbidities. Endoscopic biliary stenting (EBS) mostly needed for ECC. In this study, we aimed to investigate the prognostic factors overall survival (OS) predicting patients eligible chemotherapy after EBS in We retrospectively screened 153 advanced ECC who underwent jaundice make chemotherapy. Patient's clinical laboratory parameters were recorded. OS was estimated by Kaplan–Meier...

10.1097/md.0000000000014556 article EN cc-by-nc Medicine 2019-02-01

To determine the prevalence and clinical impact of transfusion-transmitted virus (TTV) DNA in patients with chronic liver diseases Southeast Anatolia region Turkey where hepatitis B C viral infections are endemic.Patients diagnosed disease by clinical, biochemical histologic means were enrolled study. Serum samples 60 (19 males, 41 females) diseases, 45 healthy volunteer blood donors as a control group collected. The consisted 11 B, 44 5 unknown etiology. Presence TTV was investigated...

10.1159/000070755 article EN Medical Principles and Practice 2003-01-01

The purpose of this study is to analyze the protective effect combining N-acetylcysteine (NAC) and hyberbaric oxygen (HBO) treatment in lung tissue during acute pancreatitis. Sixty Sprague-Dawley male rats were randomly divided into five groups; Group I; Control group (n=12), II; pancreatitis III; + NAC IV; HBO V; (n=12). was applied postoperatively for 5 days, twice a day at 2.5 fold absolute atmospheric pressure 90 min. Lung obtained measuring malondialdehyde (MDA), superoxide dismutase...

10.33549/physiolres.930765 article EN cc-by-nc Physiological Research 2006-01-01

The hepatitis G virus (HGV) and transfusion-transmitted (TTV) are recently defined viruses that the pathogenic roles in liver diseases still not clear. It has been well known some virus, such as C, might have an affinity to pancreatic islet cells. To investigate relationship between newly diabetes mellitus (DM), we studied prevalence of TTV HGV a type 2 diabetic patient population. Serum samples 60 patients with DM 45 healthy volunteers control were taken. RNA DNA was investigated by...

10.1111/j.1742-1241.2004.00288.x article EN International Journal of Clinical Practice 2004-12-16

Hepatitis C virus (HCV) infection is a common disease that causes liver cirrhosis, hepatocellular carcinoma, and extra hepatic manifestations with high mortality morbidity rates. This study aimed to present real-life experiences results of treatment HCV direct-acting antiviral agents (DAAs) from the Euro-Asian region, including Turkey Azerbaijan.A total 1224 patients chronic were treated DAAs in accordance international guidelines for management infection. The mean age was 58.74±14.75 years,...

10.5152/tjg.2020.19440 article EN The Turkish Journal of Gastroenterology 2020-03-05

Data collection: we analyzed prospectively-collected data from our Turkish multi-institutional collaborating HCC working group [30,31], containing information on survival, baseline clinical and tumor characteristics 1584 patients who had full parameter data, including CT scan maximum diameter (MTD), number of nodules presence PVT;

10.15761/jts.1000421 article EN Journal of Translational Science 2021-01-01

We describe the diagnosis of a 77-year-old woman admitted to our outpatient department with 3-month history abdominal bloating and distension. Abdominal computed tomography revealed large cystic lesion in posterior segment right hepatic lobe, separated germinal layer widespread ascites dense internal echoes septal appearance. The result serum Echinococcus indirect haemagglutination test was positive findings were indicative spontaneous rupture hydatid cyst into peritoneal cavity without...

10.7196/samj.5935 article EN cc-by-nc South African Medical Journal 2012-06-28

Daclatasvir and asunaprevir dual therapy is approved for the treatment of HCV genotype 1b infection in several countries. To evaluate efficacy safety daclatasvir Turkish patients. Sixty-one patients with were enrolled early access program. Most difficult-to-treat category. Patients visited at each 4 week throughout follow-up period. Laboratory findings adverse events recorded visit. Fifty-seven 61 completed 24 weeks treatment. Two died as a result underlying diseases 12-14th stopped...

10.5604/16652681.1226817 article EN cc-by-nc-nd Annals of Hepatology 2016-12-23

Background/Aims: This study aimed to evaluate the real-life efficacy and tolerability of direct-acting antiviral treatments for patients with chronic hepatitis C (CHC) with/without cirrhosis in Turkish population.Material Methods: A total 4,352 CHC from 36 different institutions Turkey were enrolled.They received ledipasvir (LDV) sofosbuvir (SOF)±ribavirin (RBV) ombitasvir/paritaprevir/ritonavir±dasabuvir (PrOD)±RBV 12 or 24 weeks.Sustained virologic response (SVR) rates, factors affecting...

10.5152/tjg.2020.20696 article EN The Turkish Journal of Gastroenterology 2021-01-29

rate of Acinetobacter baumannii infection among SOTR patients is 1.4 to 6.1%, and the mortality ranges from 39 80%. 3 In this case report, we assessed clinical presentation treatment options in a liver transplant recipient who had infected with A. postoperative early term period. CASE REPORTA 49-year-old female patient was hospitalized acute hepatic failure taken into intensive care unit.Cadaveric transplantation accomplished within 12 hours after an emergency called out National Transplant...

10.5005/jp-journals-10018-1192 article EN Euroasian Journal of Hepato-Gastroenterology 2010-09-01

To evaluate the histopathological changes in liver after oral antiviral therapy patients with chronic hepatitis B.A total of 79 HBeAg-negative and positive who had been on lamivudine, entecavir, or tenofovir disoproxil for at least 3 years prior to inclusion were enrolled between March 2015 2016, retrospectively. There 23 21 35 tenofovir. All underwent a follow-up biopsy. Biochemical, serological, virological data recorded all compared treatment agents. Results: Histological activity index...

10.15537/smj.2018.10.23056 article EN Saudi Medical Journal 2018-10-01

Giriş ve Amaç:Üst gastrointestinal sistem kanamaları Gastroenterolojinin önemli uğraş alanlarından birini oluşturmaktadır. Bu hastalarda ön klinik değerlendirme en basamaklardan Bazı hastalar kanama tanısı ile gönderilmelerine rağmen aktif izlenmemektedir. çalışmada, üst kanaması merkezimize refere edilen hastalardan kanamalı bunların endoskopi bulguları değerlendirildi. Gereç Yöntem:Toplam 20 aylık bir sürede kliniğimiz Endoskopi Ünitesi'ne çalışmaya dahil edildi. hastaların oranları...

10.17940/endoskopi.74813 article TR Endoskopi Gastrointestinal 2015-04-03
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