- Liver Disease Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Helicobacter pylori-related gastroenterology studies
- Hepatitis C virus research
- Inflammation biomarkers and pathways
- Gallbladder and Bile Duct Disorders
- Gastric Cancer Management and Outcomes
- Pharmacology and Obesity Treatment
- Dialysis and Renal Disease Management
- Gastroesophageal reflux and treatments
- Inflammatory Bowel Disease
- Hepatitis B Virus Studies
- Obesity and Health Practices
- Blood Pressure and Hypertension Studies
- Biliary and Gastrointestinal Fistulas
- Diagnosis and treatment of tuberculosis
- Dysphagia Assessment and Management
- Kidney Stones and Urolithiasis Treatments
- Hedgehog Signaling Pathway Studies
- Pediatric Urology and Nephrology Studies
- Appendicitis Diagnosis and Management
- Anesthesia and Sedative Agents
- Acute Kidney Injury Research
- Inflammatory Biomarkers in Disease Prognosis
- Soil Mechanics and Vehicle Dynamics
Atatürk University
2008-2024
Akdeniz University
2021
Erzurum Regional Training and Research Hospital
2019
Increased platelet activation contributes to cardiovascular mortality in chronic kidney disease patients (CKD). Larger platelets are more active and this increased activity had been suggested as a predictive biomarker for disease. In study, we aimed evaluate mean volume (MPV) an inflammatory marker broadened group of CKD patients. Our study is unique literature it covers all types including renal replacement therapies.200 (50 transplanted, 50 hemodialysis, peritoneal dialysis, failure stages...
Abstract BACKGROUND Neonatal feces are one of the most important sources for probiotic isolation. The purpose this study was isolation and identification Bifidobacterium spp. from neonatal evaluation in vitro properties strains including safety tests. RESULTS A total 40 isolates were obtained 14 healthy newborns' Erzurum province, Türkiye. By their rep‐PCR patterns 16S rRNA gene sequences, identified as 26 breve longum . Fifteen tolerated bile salts showed high resistance to simulated...
Ulcerative colitis (UC) is an inflammatory bowel disease characterized by mucosal inflammation. Endocan, a proteoglycan secreted endothelial cells in response to cytokines, has been reported be overexpressed conditions. In this study, we aimed evaluate the utility of endocan level determining extent and severity patients with ulcerative determine whether it can candidate marker for noninvasive evaluation monitoring since there not enough data literature.Sixty-five people were included...
This study aimed to evaluate the significance of serum salusin beta (SAL-β) levels in predicting severity acute pancreatitis (AP) patients diagnosed with this condition and assess its relationship disease prognosis.
Objective: The aim of our study was to examine the factors associated with mortality in patients who underwent percutaneous endoscopic gastrostomy (PEG) and identify biomarkers that may guide clinical practice. Methods: This retrospective observational included adults PEG placement center. Demographic data, date placement, inpatient ward, indication, time from admission post-PEG complications, outcome (discharge/mortality) were recorded. Logistic regression analysis performed 90-day 6-month...
The endoscopic retrograde cholangiopancreatography (ERCP) procedure is generally performed in patients with high comorbidity. We aimed to reduce the consumption of propofol by adding lidocaine before ERCP.Eighty ERCP ASA I-III, aged between 45-75 years, were randomly divided into two groups. Lidocaine group (group L, n = 40), received 1-mg midazolam, 1.5 mg/kg lidocaine, and 1 intravenously. control C, 40) saline same volume as group, Propofol was administered intermittent bolus doses....
Background Aim. In case of high-dose acetaminophen intake, the active metabolite can not bind to glutathione, thereby inducing cellular necrosis through binding cytosol proteins. This trial was performed histologically and biochemically investigate whether leptin protective against liver damage induced by paracetamol at toxic doses. Material Method. our trial, 30 female rats, divided into 5 groups, were used. IP administration after an hour in group which poisoning induced. The groups as...
Background and study aims: Endothelial cell specific molecule-1 (ESM-1), also known as endocan, is a soluble proteoglycan secreted by human vascular endothelial cells. In some studies, it has been found that endocan have important effects on adhesion, inflammation angiogenesis. this study, we aimed to evaluate the level in patients with pancreatitis availability of determining severity disease. Patients methods: A total 42 33 healthy individuals were included study. The serum levels...
AMAÇ: ERCP (Endoskopik retrograd kolanjiopankreatikografi) güvenilir ve etkin bir tedavi yöntemi olup bazen birtakım komplikasyonlara sebep olabilir. Bu komplikasyonların yaklaşık %1-2’si ciddi komplikasyonlar olarak tanımlanmış ancak %1’in altında ölüm oranları bildirilmiştir. Amacımız deneyimizi komplikasyon yönetimini paylaşmaktır. GEREÇ VE YÖNTEM: Sağlık Bilimleri Üniversitesi Erzurum Bölge Eğitim Araştırma Hastanesi Endoskopi ünitesinde 3 yıl boyunca yapılan 722 hasta retrospektif...
Giriş ve Amaç: Direkt etkili antiviral kombinasyonlarının, klinik çalışmalarda kronik hepatit C virüsü enfeksiyon yükünü azaltmada oldukça olduğu gösterilmiştir Avrupa Karaciğer Çalışmaları Derneği tedavi kılavuzları tarafından da tavsiye edilmektedir. Merkezimizde en önemli sağlık sorunlarından biri olan enfeksiyonunda güncel tedavide kullanılan Glecaprevir/Pibrentasvir rejiminin sonuçlarını sunmayı amaçladık. Gereç Yöntem: Bu çalışmaya, Atatürk Üniversitesi Araştırma Hastanesi...
Background/Aims: This study aimed to evaluate the real-life efficacy and tolerability of direct-acting antiviral treatments for patients with chronic hepatitis C (CHC) with/without cirrhosis in Turkish population.Material Methods: A total 4,352 CHC from 36 different institutions Turkey were enrolled.They received ledipasvir (LDV) sofosbuvir (SOF)±ribavirin (RBV) ombitasvir/paritaprevir/ritonavir±dasabuvir (PrOD)±RBV 12 or 24 weeks.Sustained virologic response (SVR) rates, factors affecting...
Background: There are many causes of the etiology hypoglycemia. Hypoglycemia is very rare in individuals without diabetes. Although it can accompany islet cell malignancies such as insulinoma, much less common solid organ tumors hepatocellular carcinoma a component paraneoplastic syndrome. Case Presentation: We present 58-year-old male patient with no additional disease, who was examined for resistant hypoglycemia and diagnosed having radiologically first time. Insulin level measured when...
Diabetic nephropathy (DN) is one of the most important causes end-stage renal failure and its prevalence found to be increasing. The presence hypertension progressive proteinuria among findings. In this study, effects double triple combinations trandolapril, telmisartan, verapamil on were investigated in diabetic patients with nephropathy. Seventy-eight (mean age: 56.11 ± 11.26 years; 47 females 31 males) overt DN included study. divided into four groups: Group I (<i>n</i>: 18, trandolapril...
Objectives: The aim of the study was to evaluate oxidative stress level in patients, diagnosed with Helicobacter pylori infection, using a novel marker (thiol/disulphide homeostasis) and compare infected individuals that healthy volunteers. Methods: A total 60 patients gastritis, erosive gastritis or ulcer by endoscopy were included biopsied. 30 H. enrolled. Medical histories, physical examination results, body mass index (BMI), hemogram, free triiodothyronine (FT3), thyroxine (FT4), thyroid...
Objectives: The incidence of tuberculous peritonitis has been reported between 0.1% and 0.7% among all tuberculosis types. This study, it was aimed to evaluate the cases with peritonitis, which an important place in differential diagnosis patients ascites, clinically, biochemically, microbiologically, histopathologically. Methods: : Forty-nine a definite clinical, radiological, histopathological formed basis our were analyzed retrospectively. Results: mean age found be 39.45 ± 19.02 years....
Abstract Background Uromodulin is a protein produced in kidney tubule cells and found the urine. levels detected serum urine provide information about renal functions reserve. Methods In this study, individuals with normal functions; short-term changes uromodulin both were evaluated before after contrast agent administration 86 patients included study. Serum measured 24 hours administration. Results Although there was no significant change glomerulifiltration rate (98.7±17.5, 100.8±18.5,...
Aim: Eating disorders (EDs), dysfunctional attitudes (DAs), and limitation of movement due to kinesiophobia, which are more common in patients with type 2 diabetes mellitus (T2DM), may contribute poor metabolic control, weight gain, disregard for treatment, an increased prevalence microvascular macrovascular complications; however, current evidence is limited small studies restricted measures. In this study, these characteristics were assessed T2DM relative controls, factors independently...
Many treatment protocols are used in Helicobacter pylori eradication within the framework of factors such as antibiotic resistance, drug side effects, patient compliance, and regional differences.H. was diagnosed with upper gastrointestinal system endoscopic biopsy Internal Diseases Gastroenterology Endoscopy Unit Atatürk University Medical Faculty Hospital; a total 229 patients over age 18 were evaluated prospectively by dividing them into 3 groups applying different H. protocols.A who...