Daniel Castrillejo
A5049758274- Respiratory viral infections research
- Influenza Virus Research Studies
- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- COVID-19 epidemiological studies
- Pneumonia and Respiratory Infections
- HIV/AIDS Research and Interventions
- Aging, Health, and Disability
- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Data-Driven Disease Surveillance
- Bacterial Infections and Vaccines
- Virology and Viral Diseases
- HIV, Drug Use, Sexual Risk
- Mosquito-borne diseases and control
- Hepatitis C virus research
- Pneumocystis jirovecii pneumonia detection and treatment
- Animal Disease Management and Epidemiology
- Dementia and Cognitive Impairment Research
- Viral Infections and Vectors
- Whipple's Disease and Interleukins
- Hepatitis B Virus Studies
- COVID-19 Clinical Research Studies
- HIV-related health complications and treatments
- COVID-19 Digital Contact Tracing
Consejería de Salud y Consumo
2016-2024
Direccion General de Epidemiologia
2024
Consejería de Educación de la Junta de Castilla y León
2012-2021
Xunta de Galicia
2020-2021
During June 2022, Spain was one of the countries most affected worldwide by a multicountry monkeypox outbreak with chains transmission without identified links to disease-endemic countries. We provide epidemiologic features cases reported in and coordinated measures taken respond this outbreak.
In September 2015, the four-component, protein-based meningococcal serogroup B vaccine (4CMenB; Bexsero) became available for private purchase in Spain.We conducted a nationwide matched case-control study to assess effectiveness of 4CMenB preventing invasive disease children. The included all laboratory-confirmed cases children younger than 60 months age between October 5, and 6, 2019, Spain. Each case patient was with four controls according date birth province. vaccination status patients...
Abstract Background In 2021–2022, influenza A viruses dominated in Europe. The I‐MOVE primary care network conducted a multicentre test‐negative study to measure vaccine effectiveness (VE). Methods Primary practitioners collected information on patients presenting with acute respiratory infection. Cases were A(H3N2) or A(H1N1)pdm09 RT‐PCR positive, and controls virus negative. We calculated VE using logistic regression, adjusting for site, age, sex, onset date, presence of chronic...
ABSTRACT Background Data from the sentinel surveillance system of severe acute respiratory infections in Spain were used to estimate impact administration nirsevimab children born 1 April 2023 onwards. Methods Estimated RSV hospitalisations < 1‐year‐olds during weeks 40, 2023, 8, 2024, compared number that would be expected after accounting for background change circulation 2023/24 season, 2022/23. Results We estimated 9364–9875 less than expected, corresponding a 74%–75% reduction.
El deterioro cognitivo es una entidad clínica en la que las funciones intelectuales están parcial o totalmente alteradas y supone un problema de salud pública reto para los servicios sanitarios sociales. objetivo este trabajo estimar prevalencia estos trastornos población mayor 65 años consulta atención primaria 5 redes centinelas sanitarias. Se realizó el test Mini-Cog cribado muestra pacientes acudieron a su médico familia 4 días seleccionados al azar. La confirmación se hizo con...
In Spain, the influenza vaccine effectiveness (VE) was estimated in last three seasons using observational study cycEVA conducted frame of existing Spanish Influenza Sentinel Surveillance System. The objective to estimate against medically attended, laboratory-confirmed influenza-like illness (ILI) among target groups for vaccination Spain 2011–2012 season. We also studied VE early (weeks 52/2011-7/2012) and late 8-14/2012) phases epidemic according time since vaccination. Medically attended...
We present early estimates of influenza vaccine effectiveness (VE) in the population targeted for vaccination, during 25 December 2011 to 19 February 2012. The adjusted VE was 55% (95% CI: 3 79) against any type virus and 54% 1 A(H3N2) virus. This suggests a moderate protective effect late epidemic with limited match between circulating strains.
Acute flaccid paralysis (AFP) surveillance is key for global polio eradication. It allows detecting poliovirus (PV) reintroductions from endemic countries. This study describes AFP in Spain 1998 to 2015. During this time, 678 cases were reported the Spanish National Surveillance Network. The mean notification rate was 0.58 cases/100,000 population under 15 years old (range: 0.45/100,000-0.78/100,000). Two periods (P) are described: P1 (1998-2006) with ranging 0.66/100,000 0.78/100,000,...
Cognitive impairment, a clinical entity causing complete or partial intellectual dysfunction, is major public health concern that poses challenge for and social services. The purpose of this study to estimate the prevalence disorder in people aged 65 older visiting primary care physician 5 sentinel networks. A sample patients their doctor on 4 randomly selected days completed Mini-Cog screening test. Diagnosis cognitive impairment was confirmed with Mini-Mental State Examination Alzheimer's...
Importance In the context of emerging SARS-CoV-2 variants or lineages and new vaccines, it is key to accurately monitor COVID-19 vaccine effectiveness (CVE) inform vaccination campaigns. Objective To estimate vaccines administered in autumn winter 2022 2023 against symptomatic infection (with all circulating viruses XBB lineage particular) among people aged 60 years older Europe, compare different CVE approaches across exposed reference groups used. Design, Setting, Participants This...
Adjusted early estimates of the 2013/14 influenza vaccine effectiveness (VE) in Spain for all age groups was 35% (95% CI: ?9 to 62), 33% ?33 67) and 28% 61) against any virus type, A(H1N1)pdm09 A(H3N2) viruses, respectively. For population targeted vaccination, adjusted VE 44% ?11 72), 36% ?64 75) 42% ?29 74), These preliminary results suggest a suboptimal protective effect circulating viruses.
We aimed to estimate influenza vaccine effectiveness (VE) against laboratory-confirmed during three seasons (2010/11 2012/2013) in Spain using surveillance data and compare the results with obtained by cycEVA study, Spanish component of Influenza Monitoring Vaccine Effectiveness (I-MOVE) network. used test-negative case–control design, from Sentinel Surveillance System (SISS) or study. Cases were patients predominant virus each season, controls those testing negative for any virus....
ABSTRACT We estimated XBB.1.5 vaccine effectiveness (VE) against symptomatic SARS‐CoV‐2 infection among adults aged ≥ 65 years during the 2023/2024 JN.1 lineage‐predominant period in a European multi‐country test‐negative case–control study at primary care level. VE adjusted by site, age, sex, chronic conditions and onset date. included 220 cases 1733 controls. The was 48% (95% CI: 12–71), 23% −11–48) 5% −92–56) those with symptom 1–5, 6–11, 12 weeks after vaccination, respectively. provided...
A second-generation surveillance system of people infected with human immunodeficiency virus (HIV) has been implemented in Spain. Behavioural and clinical data were collected between 2002 2011 through an annual one-day, cross-sectional survey public hospitals, including all in- outpatients receiving HIVrelated care on the day. Mean age increased over time (from 38.7 years to 43.8 2011) 68.4% 7,205 subjects male. The proportion migrants from 6.1% 15.9%, while who inject or used drugs (PWID...
Abstract Background HIV infection has become a chronic disease and well-being of people living with (PLHIV) is now particular concern. The objectives this paper were to describe self-rated health among PLHIV, on ART virally suppressed analyse its determinants. Methods Data obtained from second-generation surveillance system based cross-sectional one-day survey in public hospitals. Epidemiological clinical data collected HIV-infected inpatients outpatients receiving HIV-related care the day...