A5082470527- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Viral gastroenteritis research and epidemiology
- Malaria Research and Control
- Hepatitis C virus research
- Bacteriophages and microbial interactions
- Hepatitis B Virus Studies
- Bone health and osteoporosis research
- Vector-borne infectious diseases
- Diphtheria, Corynebacterium, and Tetanus
- Liver Disease Diagnosis and Treatment
- Viral Infections and Outbreaks Research
- Bacterial Identification and Susceptibility Testing
- Escherichia coli research studies
- Salmonella and Campylobacter epidemiology
- Animal Virus Infections Studies
- Virus-based gene therapy research
- Insect symbiosis and bacterial influences
- Dental Research and COVID-19
- Infective Endocarditis Diagnosis and Management
- Dental Health and Care Utilization
- SARS-CoV-2 and COVID-19 Research
- Monoclonal and Polyclonal Antibodies Research
- Antimicrobial Resistance in Staphylococcus
- Dental Trauma and Treatments
Institutul Cantacuzino
2008-2024
Healthcare Technology Innovation Centre
2022
Indian Institute of Technology Madras
2022
All India Institute of Medical Sciences
2022
National Institute of Epidemiology
2022
Indian Council of Medical Research
2022
Sri Ramachandra Institute of Higher Education and Research
2022
European Society of Clinical Microbiology and Infectious Diseases
2021
Institute for Research and Development
2018-2021
Institute of Virology of the Slovak Academy of Sciences
2021
The novel GII.P17-GII.17 norovirus genotype has been reported as cause of gastroenteritis outbreaks in China and Japan since the winter season 2014/15, replacing pandemic strain GII.4 Sydney 2012. These emergent strains have also sporadically on other continents than Asia. isolates, similar to Kawasaki308 2015, were identified three patients during a large outbreak acute affecting 328 people Romania, neighbouring localities, 2015.
Lineage 2 West Nile virus (WNV), previously found only in sub-Saharan Africa and Madagascar, was identified Hungary 2004 has rapidly expanded Europe the past decade. Following a significant outbreak of fever with neurological cases caused by lineage 1 WNV Romania 1996, scattered have been recorded south-east country each transmission season. Another outbreak, affecting larger area WNV, 2010. We analysed human sera from neuroinvasive mosquitoes, sampled south-eastern between 2011 2013, for...
West Nile virus (WNV) is endemic in southeastern Romania and, after the unprecedented urban epidemic Bucharest 1996 caused by lineage 1 WNV, cases of fever have been recorded every year. Furthermore, a new outbreak occurred 2010, this time produced 2 WNV belonging to Eastern European clade (Volgograd 2007-like strain), which was detected humans and mosquitoes following years.We report here, for first time, emergence, 2015, monophyletic Central/Southern group strains replaced 2016, previously...
Importance In the context of emerging SARS-CoV-2 variants or lineages and new vaccines, it is key to accurately monitor COVID-19 vaccine effectiveness (CVE) inform vaccination campaigns. Objective To estimate vaccines administered in autumn winter 2022 2023 against symptomatic infection (with all circulating viruses XBB lineage particular) among people aged 60 years older Europe, compare different CVE approaches across exposed reference groups used. Design, Setting, Participants This...
Staphylococcus (S.) aureus and Pseudomonas (Ps.) aeruginosa are two of the most frequently opportunistic pathogens isolated in nosocomial infections, responsible for severe infections immunocompromised hosts. The frequent emergence antibiotic-resistant S. Ps. strains has determined development new strategies order to elucidate different mechanisms used by these bacteria at stages infectious process, providing scientists with procedures preventing, or least improving, control infections....
Abstract We describe a series of severe neuroinvasive infections caused by Toscana virus, identified real-time reverse transcription PCR testing, in 8 hospitalized patients Bucharest, Romania, during the summer seasons 2017 and 2018. Of patients, 5 died. Sequencing showed that circulating virus belonged to lineage A.
Culex pipiens sensu lato has been documented as West Nile virus (WNV) vector in southeastern Romania. Bucharest, the densely populated capital city of Romania, and surrounding Ilfov county are WNV hotspots. In this area, morphologically indistinguishable biotypes Cx. pipiens, namely molestus, usually differentiated by their behavioral physiological traits. Their involvement transmission, suggested entomological investigations, was not previously for each biotype. We used a Real-Time PCR...
During an entomological investigation carried out in Bucharest and surroundings fall of 2012, 45 adult mosquitoes (38 females 7 males) Aedes albopictus were collected a neighborhood from the southern area city. The morphological identification species was further confirmed by sequencing 2 mitochondrial DNA markers: cytochrome c oxidase subunit I NADH dehydrogenase 5 genes. again 2013 same July until October. late summer found also another location city, downtown Bucharest. Larvae water...
IntroductionAt the beginning of 2016, an increase in paediatric haemolytic uremic syndrome (HUS) cases was observed Romania. The microbiological investigations allowed isolation Shiga toxin-producing Escherichia coli (STEC) O26 as causative agent from most cases. Methods: An enhanced national surveillance HUS and severe diarrhoea established across country following identification first carried out until August 2016. A total 15 strains were isolated 10 five Strains characterised by virulence...
Usutu virus (USUV) is an emergent arbovirus in Europe causing mortality bird populations. Similar to West Nile (WNV), USUV maintained sylvatic cycles between mosquito vectors and reservoirs. Spillover events may result human neurological infection cases. Apart from indirect evidence provided by a recent serological study wild birds, the circulation of Romania was not assessed. We aimed detect molecular characterize circulating collected South-Eastern Romania-a well-known WNV endemic...
The zoonotic Shiga toxin-producing Escherichia coli (STEC) group is unanimously regarded as exceptionally hazardous for humans. This study aimed to provide a genomic perspective on the STEC recovered sporadically from humans and have foundation of internationally comparable data. Fifty clinical isolates, representing culture-confirmed infections reported by Reference Laboratory between 2016 2023, were subjected whole-genome sequencing (WGS) analysis sequences interpreted using both...
determine whether hepatitis C virus (HCV) core substitutions play a role in the response to interferon-
Corynebacterium diphtheriae is the etiological agent of diphtheria, a potential fatal disease caused by corynephage toxin. The expression this diphtheria toxin controlled via an iron‐dependent repressor with various functions (DtxR). Some mutations in dtxR gene are associated diminished activity or even total loss DtxR function. We conducted molecular study to characterize alleles harbored 34 isolates C. recovered from Romanian patients between 1961 and 2007. Three seven identified have not...
Culex pipiens and molestus mosquitoes are the vectors of West Nile virus in south-eastern Romania, an area intense circulation human transmission this virus. The level insecticide resistance for mosquito populations region has not been previously assessed. collected between 2018 2019 Romania from different habitats were subjected to biotype identification by real-time PCR. Substitutions causing organophosphates carbamates (F290V G119S acetylcholinesterase 1) pyrethroids (L1014F voltage gated...
Hemorrhagic fever with renal syndrome (HFRS) has been confirmed by serological methods during recent years in Romania. In the present study, focus-reduction neutralization tests (FRNT) Dobrava hantavirus (DOBV) as causative agent some HFRS cases, but could not distinguish between DOBV and Saaremaa virus (SAAV) infections other cases. was detected a DOBV-specific TaqMan assay sera of nine patients out 22 tested. Partial sequences M genomic segment were obtained from three revealed circulation...