A5016376888- Synthetic Organic Chemistry Methods
- Chemical Synthesis and Reactions
- Asymmetric Synthesis and Catalysis
- Chemical Synthesis and Analysis
- Carbohydrate Chemistry and Synthesis
- Multicomponent Synthesis of Heterocycles
- Oxidative Organic Chemistry Reactions
- Marine Sponges and Natural Products
- Synthesis and Catalytic Reactions
- Sulfur-Based Synthesis Techniques
- Traditional and Medicinal Uses of Annonaceae
- Chemical synthesis and alkaloids
- Microbial Natural Products and Biosynthesis
- Asymmetric Hydrogenation and Catalysis
- Synthesis and biological activity
- Catalytic C–H Functionalization Methods
- Microwave-Assisted Synthesis and Applications
- Synthesis of Organic Compounds
- Synthesis and Biological Evaluation
- Catalytic Alkyne Reactions
- Synthesis of Indole Derivatives
- Ionic liquids properties and applications
- Catalytic Cross-Coupling Reactions
- Cyclopropane Reaction Mechanisms
- Click Chemistry and Applications
Indrashil University
2018-2024
Indian Institute of Chemical Technology
2014-2023
Academy of Scientific and Innovative Research
2014-2020
Institute of Chemical Technology
2020
University of Hyderabad
2015-2020
Technion – Israel Institute of Technology
2020
Stockholm University
2020
Chulabhorn Research Institute
2020
Ural Federal University
2020
Ural Branch of the Russian Academy of Sciences
2020
Lithium perchlorate is found to catalyze efficiently the electrophilic substitution reactions of indoles with aldehydes and ketones in diethyl ether afford corresponding bis(indolyl)methanes high yields. LiOTf also be an efficient catalyst for synthesis these compounds.
Lithium perchlorate efficiently catalyzes the three-component condensation reaction of aldehyde, β-keto ester and urea in refluxing acetonitrile to afford corresponding dihydropyrimidinones high yields under neutral conditions. LiOTf is also found be an efficient catalyst for synthesis from urea.
Ceric ammonium nitrate efficiently catalyzes the three component condensation of an aldehyde, β-ketoester and urea in methanol to afford corresponding dihydropyrimidinones excellent yields under sonication. Other oxidants such as manganese triacetate Oxone were also found catalyze this transformation similar conditions.
Indole and 2-methylindole undergo conjugate addition with electron-deficient olefins in the presence of a catalytic amount InCl3 at ambient temperature to afford corresponding Michael adducts excellent yields high selectivity.
Abstract Indium and its salts have emerged as promising catalysts for effecting various functional group transformations in last two decades. There are a great number of reported reactions involving indium reagents; the versatility applicability these makes it hot field to explore, attracts much interest from organic chemists. The development reagents C–C bond‐formation reactions, coupling asymmetric synthesis presence chiral‐metal ligand complexes, etc. has made this more attractive....
A novel method has been devised for the synthesis of 2,4,5-trisubstituted pyrrole derivatives through coupling α-diazoketones with β-enaminoketones and esters using 10 mol % Cu(OTf)2. wide range 2,3-disubstituted indole were also prepared from 2-aminoaryl or alkyl ketones. The synthetic versatility this approach exemplified in formal homofascaplysin C.
o-Aminoaryl ketones undergo smooth condensation with α-methylene on the surface of silver heteropoly acid (Ag3PW12O40) under mild reaction conditions to afford corresponding polysubstituted quinolines in excellent yields high selectivity. The catalyst can be recovered by simple filtration and recycled subsequent reactions.
Aldimines undergo nucleophilic addition with diethyl phosphite in the presence of a catalytic amount zirconium tetrachloride at ambient temperature to afford corresponding α-aminophosphonates high yields selectivity.
4-Alkyl or aryl substituted Hantzsch 1,4-dihydropyridines are aromatized to the corresponding pyridines in high yields by iodine refluxing methanol. The method tolerates several substituents such as alkyl, benzyl, and heterocyclic groups present 4-position of pyridines.
The direct sulfenylation of indoles with aromatic thiols has been accomplished in the presence 20 mol% FeCl3 refluxing acetonitrile to produce 3-arylthioindoles relatively good excellent yields and high selectivity. This method works even 2-unsubstituted indoles.
Abstract Efficient one-pot synthesis of 4H-benzo[b]pyrans via a three-component cyclocondensation aryl aldehydes, malononitrile, and dimedone has been reported using CeCl3·7H2O as catalyst.