- Forensic and Genetic Research
- Molecular Biology Techniques and Applications
- Environmental DNA in Biodiversity Studies
- Forensic Anthropology and Bioarchaeology Studies
- Race, Genetics, and Society
- Identification and Quantification in Food
- Genetic Associations and Epidemiology
- Genetic diversity and population structure
- Free Radicals and Antioxidants
- Analytical Chemistry and Chromatography
- Antibiotic Resistance in Bacteria
- Forensic Toxicology and Drug Analysis
- Biofield Effects and Biophysics
- Antibiotics Pharmacokinetics and Efficacy
- Nutrition, Genetics, and Disease
- Computational Drug Discovery Methods
- Genomics and Phylogenetic Studies
- Spectroscopy and Chemometric Analyses
- Genetics and Physical Performance
- Antimicrobial Resistance in Staphylococcus
- Intellectual Property Law
- Genetically Modified Organisms Research
- Chemical and Physical Properties in Aqueous Solutions
- Protein Interaction Studies and Fluorescence Analysis
- Animal testing and alternatives
University of Reggio Calabria
2011-2025
Universidad de Alcalá
2023-2025
Australia and New Zealand Banking Group
2023
Universidade de Santiago de Compostela
2009-2012
Società Italiana di Medicina Generale
2006-2008
University of Bologna
1971-1991
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInfluence of lipophilic character on the antibacterial activity cephalosporins and penicillinsGian L. Biagi, Maria C. Guerra, Anna M. Barbaro, F. GambaCite this: J. Med. Chem. 1970, 13, 3, 511–516Publication Date (Print):May 1, 1970Publication History Published online1 May 2002Published inissue 1 1970https://doi.org/10.1021/jm00297a038RIGHTS & PERMISSIONSArticle Views216Altmetric-Citations75LEARN ABOUT THESE METRICSArticle Views are...
Previous studies showed that the epidemic of carbapenem-resistant Klebsiella pneumoniae (CR-KP) observed in Italy since 2010 was sustained mostly by strains clonal group (CG) 258 producing KPC-type carbapenemases. In framework National Antibiotic-Resistance Surveillance (AR-ISS), a countrywide survey conducted 2016 to explore evolution phenotypic and genotypic characteristics CR-KP isolates.From March July 2016, hospital laboratories participating AR-ISS were requested provide consecutive,...
Ultra-weak photon emission (UPE) provides a non-invasive method for assessing the biochemical state of biological materials. In this work, we investigated UPE in fruits various colours (red, orange, yellow, and green) potential forensic applications. Firstly, were exposed to natural sunlight 10 min, after which was measured at min intervals over three-hour period. The results indicated that, following initial induced response, all fruit types stabilised spontaneous approximately 60 darkness....
The chromatographic Rm values of three series steroids were determined by means a reversed-phase system. at 45% acetone in the mobile phase shown to be correlated with partition coefficients an ether-water However, almost equally good correlation was found when using extrapolated values. extrapolation technique could provide standard relationship between biological data and pointed out important role lipophilic character regulating activity steroids. In particular, dependence protein binding...
Due to its history, with a high number of migration events, the Mediterranean basin represents challenging area for population genetic studies. A large studies have been carried out in using different markers but no consensus has reached on landscape populations. In order further investigate genetics human populations, we typed 894 individuals from 11 populations 25 single-nucleotide polymorphisms (SNPs) located X-chromosome. overall homogeneity was found among except Morocco, which seemed...
Twenty-five 5-nitroimidazole and two 5-nitrothiazole derivatives were tested for mutagenicity as well antibacterial activity in Salmonella typhimunum TA-100 strain. Many of these compounds such metronidazole, azanidazole, nimorazole, carnidazole, ornidazole, tinidazole, etc are extensively used human chemotherapy, some them recently synthetized possible clinical trials hypoxic cell specific radiosensitizers. Both mutagenic shown 22 the test compounds. The high correlation between supports...
Oral fluids are common evidence that can be found as stains on a variety of substrates at crime scenes. The porosity the substrate may influence their collection and analysis. Moreover, companion animals, such dogs, appear in many scenarios or even involved crime. Determining source (identification classification) human canine oral fluid different scene is important prior to DNA extraction diminish laboratory cost time efforts. In present work, potential attenuated total reflection Fourier...
Background: the Investigator ESSplex SE QS Kit (Qiagen) is a next generation PCR kit that, in 60 minutes, amplifies 17 STRs markers, including 5 European Standard Set (ESS) loci, SE33 marker and locus Amelogenin for sex determination. Two Quality Sensors (QS1 QS2) are co-amplified to check performance. Since forensic laboratories carry out annually hundreds of DNA typing, we verified performance using half reaction volumes with aim improve number samples that may amplified kit, reducing...
Currently, the cosmetic industry is developing several treatments based on use of lights with different wavelengths for anti-ageing strategies and facial rejuvenation. Some have been proven to be beneficial our skincare, but their actual effects require an in-depth analysis. Ultra-weak photon emission (UPE) a spontaneous, low intensity from all living systems produced as consequence metabolic reactions (e.g., oxidative metabolism, cell division, photosynthesis, or carcinogenesis). However,...
The role of DNA damage in PCR processivity/fidelity is a relevant topic molecular investigation aged/forensic samples. In order to reproduce one the most common lesions occurring postmortem tissues, new protocol based on aqueous hydrolysis was developed vitro. Twenty-five forensic laboratories were then provided with 3.0 μg trial sample (TS) exhibiting, mean, loss 1 base 20, and weight below 300 bp. Each participating laboratory could freely choose any combination methods, leading...
The mutagenic activity of 20 5-nitroimidazoles was tested in Salmonella typhimurium TA-100 strain by means the Ames test. A multiple regression analysis using interaction term MR2 × Hb and chromatographic Rm values yielded equation: where C is molar concentration (1 M 10−6) each drug increasing revertants five times takes into account positive effect exerted substituents characterized higher refractivity (MR2) capable hydrogen bonding (Hb). It found that when electroreduction potentials (E)...
Bones and teeth often represent the only sources of DNA available for identifying human remains. in bones is generally better preserved than that soft tissues because presence hard connective tissue with a high level calcium. Because extensive mineralisation, choice an efficient extraction procedure important to minimise sampling minerals remove polymerase chain reaction (PCR) inhibitors. Some protocols are from as part Qiagen EZ1 Investigator Kit using Advanced XL automated purification...