Cadmium (Cd) has been found as an environmental pollutant in Mae Sot district, Tak province, Thailand. Prolong exposure to high levels of Cd the resident increases risk toxicity especially kidney which is primary target Cd. In order investigate early effect induced renal dysfunction, a injury molecule-1 (KIM-1), novel biomarker tubular was measured using enzyme linked immunosorbent assay (ELISA). The method validated and used quantify KIM-1 concentrations urine 700 subjects (260 men, 440...

The aim of the present study was to estimate benchmark doses (BMD) for renal effects health risk assessment residents living in Cd-polluted and non-polluted areas a Thai population.The participants consisted inhabitants aged 40 years or older who lived area (40 men 41 women) environmentally polluted Mae Sot District (230 370 located northwestern Thailand. We measured urinary blood cadmium (Cd) as markers long-term exposure β2-microglobulin (β2-MG) N-acetyl-β-D-glucosaminidase (NAG) tubular...

This study aims to summarize electronic waste (e-waste) worker health; examine associations between health and sociodemographic characteristics; metal body burden.In 2016, 131 e-waste recycling workers were enrolled in the study, completed a questionnaire, gave blood urine samples for heavy concentration assessment (lead, cadmium, copper, zinc, nickel). The relationship symptoms, general health, metals is assessed via generalized estimating equation models (adjusted age, education, sex,...

Acute non-typhoidal salmonellosis (NTS) caused by Salmonella enterica Typhimurium (STM) is among the most prevalent of foodborne diseases. A global rising antibiotic resistance strains STM raises an urgent need for alternative methods to control this important pathogen. Major human food animals which harbor in their gut are cattle, swine, and poultry. Previous studies showed that probiotic Limosilactobacillus ( Lactobacillus ) reuteri KUB-AC5 (AC5) exhibited anti- activities chicken...

Background: Informal electronic waste (e-waste) recycling is an increasingly important industry worldwide. However, few studies have studied the health risks in this group of workers. Objective: To assess associations between occupational exposures to metals and genetic instability renal markers among e-waste Methods: We recruited informal workers from a community northeastern Thailand. Participants completed questionnaire, several measurements, provided urine blood samples, which we then...

Some residents of the Mae Sot district in Thailand have suffered long-term exposure to elevated dietary levels cadmium. To test hypothesis that chronic cadmium can cause imbalance calcium dynamics and accelerate bone resorption, a group these (156 men 256 women aged ≥ 50) were selected on basis previous records urinary tested for blood cadmium, formation resorption markers, renal tubular dysfunction markers. Both genders had high markers dose–response relationship The excretion was...

To elucidate the influence of cadmium exposure on bone metabolism, associations between urinary/blood and resorption/formation markers were investigated in older exposed men women. Increased urinary cross-linked N-telopeptide type I collagen (NTx), a resorption marker, was found to be associated with increased levels parathyroid hormone, fractional excretion calcium, after adjusting for confounding factors men. In women, NTx significantly only strong relationship calcium. Risk metabolic...

Developmental cadmium exposure in vivo disrupts mammary gland differentiation, while of breast cell lines to causes invasion consistent with the epithelial-mesenchymal transition (EMT). The effects on normal human stem cells have not been measured. Here, we quantified reduction mammoplasty patient-derived proliferation and differentiation. Using mammosphere assay organoid formation 3D hydrogels, tested 2 physiologically relevant doses cadmium, 0.25 2.5 µM, for molecular alterations using...

Existing electronic travel aids have not been widely used by the visually impaired communities worldwide due to their low performance, unattractive appearance, impracticality, and high cost. This paper proposes iSonar – a miniaturized, cost obstacle warning device for those who are impaired. It was designed in accordance with specific requirements of Thailand's users. To avoid collision, an ultrasonic transducer is detect obstacles providing tactile feedback different vibration frequencies...

DNA methylation changes with age, and may serve as a biomarker of aging. Cadmium (Cd) modifies cellular processes that promote aging disrupts globally. Whether Cd by influencing establishment age-associated marks is currently unknown. In this pilot study, we characterized profiles in > 450 000 CpG sites 40 non-smoking women (age 40–80) differentially exposed to environmental from Thailand. Based on specific gravity adjusted urinary Cd, classified them high (HE) low (LE) age-matched within 5...

Abstract Objectives To assess pesticide exposure and understand the resultant health effects of agricultural workers in Northern Thailand. Methods This was a cross-sectional study. We quantified to pesticides, including chlorpyrifos, methomyl, metalaxyl, by air sampling liquid chromatography/mass spectrometry. estimated differences self-reported outcomes, complete blood counts, cholinesterase activity, serum/urine calcium creatinine concentrations at baseline between farmworkers comparison...

The informal recycling of electronic waste ("e-waste") is a lucrative business for workers in low- and middle-income countries across the globe. Workers dismantle e-waste to recover valuable materials that can be sold income. However, expose themselves surrounding environment hazardous agents during process, including toxic metals like lead (Pb). To assess which tools, tasks, job characteristics result higher concentrations urine blood levels among workers, ten random samples 2 min video...

Silica and noise are highly prevalent occupational exposures in the stone processing industry. Monitoring for silica expensive tasks that may be especially difficult to perform low-resource settings, but exposure awareness is vital protecting worker health. This study evaluated personal measurements at a facility northern Thailand investigate differing potentials risk overexposure among varying job categories. Our research team performed repeated respirable on 46 workers, over three separate...

Abstract Go/no-go decisions require engineering design teams to evaluate whether a concept is worth further investment of resources. These can be difficult when product success depends on multiple stakeholders in addition the end-user. This study proposes Stakeholder Agreement Metric (SAM) framework estimate level agreement between stakeholder preferences via distance optimal designs calculated from preference model derived conjoint analysis. The was tested an empirical case describing and...

Papanicolaou test is widely used to screening cervical cancer but low attend rate. There one mountainous area found high participation rate.This study aimed determine the factors associated with successful Pap among Lahu hill tribe women.The quantitative cross-sectional was in this study. Data were collected from 650 women by simple random sampling. The interview forms reliability coefficient and validity of 0.78 0.91 administered participants. data analyzed using descriptive statistics...

Introduction Coronavirus disease (COVID-19) is an infectious caused by the SARS-CoV-2-virus. COVID-19 has officially been declared as latest in list of pandemics WHO at start 2020. This study investigates associations among decrease economic activity, gender, age, and psychological distress during pandemic considering status education level countries using multinational surveys. Methods Online self-report questionnaires were administered 15 which spontaneously participate to 14,243...

Farming is an important occupation in Thai hill tribe communities, which are often remote, and lack other economic opportunities along with basic educational, health care, occupational safety services. Additionally, these communities have a unique culture language.The present study was conducted northern Thailand to evaluate pesticide exposures associated impacts among farmers, compare them farmers.Lahu farmers mountain community were recruited by public hospital staff, reference group of...

Conjoint experiments (CEs) provide designers with insights into consumer preferences and are one of several user-based design approaches aimed at meeting users' needs. Traditional CEs require participants to evaluate products based on two-dimensional (2D) visual representations or written lists attributes. Evidence suggests that product can affect how perceive attributes, an effect might be exacerbated in a Low- Middle-Income Country setting where have seldom been studied. This study...

Control of the COVID-19 pandemic requires significant changes in people’s health behaviors. We offer this multidisciplinary perspective on extent compliance with social distancing recommendations and coping these measures around globe first months pandemic. present descriptive data from our survey 17,650 respondents across 18 countries territories June 2020. The majority worried about contracting virus. Nearly all engaged at least some preventive behaviors, particularly handwashing, mask...

<h3>Introduction</h3> Paddy fields in Mae Sot, Tak province of Thailand are polluted with cadmium (Cd) over safe level. Farmers exposed Cd from contaminated rice consumption and the high prevalence kidney dysfunction was shown population. Bone fracture is another related pathology which elderly exposure The identification risk individuals will be advantageous to provide suitable health promotion prevent severe pathology.This study done compare bone between glomerular dysfunction, proximal...