- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Diagnosis and treatment of tuberculosis
- Infectious Diseases and Tuberculosis
- Infectious Encephalopathies and Encephalitis
- Fungal Infections and Studies
- Pleural and Pulmonary Diseases
- Cancer Immunotherapy and Biomarkers
- Pneumonia and Respiratory Infections
- Breast Lesions and Carcinomas
- Inflammasome and immune disorders
- Immune Cell Function and Interaction
- Bacterial Infections and Vaccines
- Streptococcal Infections and Treatments
- Metastasis and carcinoma case studies
- Hematological disorders and diagnostics
- Immune Response and Inflammation
Catholic University of Korea
2003
Daejeon Catholic University
2002
Catholic University of America
2000-2002
Chungnam National University
1995
ABSTRACT The secreted 30-kDa antigen (Ag) of Mycobacterium tuberculosis directly stimulates Th1-type protective cytokine responses in healthy tuberculin reactors but not patients with active (TB). To examine the profiles attributable to Th1 suppression associated TB, interleukin-12 (IL-12), IL-18, and IL-10 production response a 30- or 32-kDa Ag 16 pulmonary TB 24 controls was investigated by enzyme-linked immunosorbent assay. In patients, IL-12 p40, as well gamma interferon (IFN-γ),...
Epidemiological data of Bordetella pertussis infection among adolescents and adults are limited in Korea. Patients (≥ 11 yr age) with a bothersome cough for less than 30 days were enrolled during 1-yr period at 22 hospitals Nasopharyngeal swabs collected polymerase chain reaction (PCR) bacteriologic culture. In total, 490 patients finally enrolled, 34 (6.9%) tested positive B. pertussis; duration (14.0 [7.0-21.0 days]) age distribution diverse. The incidence was the highest secondary...
Interleukin-18 (IL-18) has multiple important pro-inflammatory effects, including the induction of interferon-gamma (IFN-gamma) in various diseases. In this study, we investigated IL-18-producing activities human pulmonary and pleural tuberculosis (TB) response to purified protein derivative (PPD) antigen (Ag) from Mycobacterium tuberculosis. The most significant IL-18 production was found chronic refractory TB (CRTB) patients. However, IFN-gamma CRTB patients significantly less than that...
Background: Our previous study showed that purified protein derivative (PPD)stimulated pleural mononuclear cells (PMC) from tuberculous pleurisy (Tbp) produced significantly more IFN-γ (10to 70-fold) after in vitro PPD stimulation than freshly isolated malignant pleurisy. The present was designed to determine whether blocking the CD40-CD40 ligand (CD40L) interaction decreases IFNγ production by altering IL-12 levels. Methods: and neutralizing anti-CD40L antibody treatment compared efficacy...
Mammary tuberculosis is a rare entity. The incidence of the disease varies from 0.025% to 4.5% all surgically treated breast diseases. surgical resection required for diagnosis mammary tuberculosis, since clinician may confuse mastitis with either carcinoma or abscess. Treatment combination and chemotherapy. We report case diagnosed by fine-needle aspiration biopsy (FNAB), along review literature.