A5046442548- Turfgrass Adaptation and Management
- Plant Taxonomy and Phylogenetics
- Genetic diversity and population structure
- Hepatitis C virus research
- Wheat and Barley Genetics and Pathology
- Gut microbiota and health
- Plant Stress Responses and Tolerance
- Plant Disease Resistance and Genetics
- Rangeland and Wildlife Management
- Genetic Mapping and Diversity in Plants and Animals
- Chromosomal and Genetic Variations
- Cancer Immunotherapy and Biomarkers
- Lipid metabolism and biosynthesis
- Genetically Modified Organisms Research
- Polysaccharides and Plant Cell Walls
- Plant and animal studies
- Liver Disease Diagnosis and Treatment
- Nanoparticles: synthesis and applications
- Research in Cotton Cultivation
- Plant responses to elevated CO2
- Bioenergy crop production and management
- Hepatitis B Virus Studies
- Diet and metabolism studies
- Plant pathogens and resistance mechanisms
- Seedling growth and survival studies
Yangzhou University
2018-2025
Xuzhou Medical College
2008-2024
University of Toronto
2024
Agriculture and Agri-Food Canada
2024
Ottawa Research and Development Centre
2024
Nanchang University
2024
Tianjin University of Science and Technology
2023
Affiliated Hospital of Xuzhou Medical College
2008-2023
Nanjing Medical University
2019
Henan Agricultural University
2008-2016
Abstract Accumulating evidence suggests that ketogenic diets (KDs) mediate the rise of circulating ketone bodies and exert a potential anti-inflammatory effect; however, consequences this unique diet on colitis remain unknown. We performed series systematic studies using dextran sulfate sodium (DSS) animal model inflammatory colitis. Animals were fed with KD, low-carbohydrate (LCD), or normal (ND). Germ-free mice utilized in validation experiments. Colon tissues analyzed by transcriptome...
Abstract Emerging research has revealed regulation of colorectal cancer metabolism by bacteria. Fusobacterium nucleatum (Fn) plays a crucial role in the development cancer, however, whether Fn infection modifies patients with remains unknown. Here, LC-MS/MS-based lipidomics identified upregulation cytochrome P450 monooxygenases, primarily CYP2J2, and their mediated product 12,13-EpOME tumors mouse models, which increased invasive migratory ability cells vivo vitro regulating...
Fusobacterium nucleatum (F. nucleatum) promotes intestinal tumor growth and its relative abundance varies greatly among patients with CRC, suggesting the presence of unknown, individual-specific effectors in F. nucleatum-dependent carcinogenesis. Here, we identify that is enriched preferentially KRAS p.G12D mutant CRC tissues contributes to colorectal tumorigenesis Villin-Cre/Kras
Introduction Infectious diseases are major causes of morbidity and mortality worldwide, necessitating the rapid identification accurate diagnosis pathogens. While unbiased metagenomic next-generation sequencing (mNGS) has been extensively utilized in clinical pathogen scientific microbiome detection, there is limited research about application nanopore platform-based mNGS diagnostic performance various infectious fluid samples. Methods In this study, we collected 297 suspected fluids from 10...
To investigate the cholesterol-lowering effects of alfalfa saponin extract (ASE) and its regulation mechanism on some key genes involved in cholesterol metabolism, 40 healthy 7 weeks old male Sprague Dawley (SD) rats were randomly divided into four groups with 10 each group: control group, hyperlipidemic ASE treatment prevention group. The body weight gain, relative liver serum lipid 1evels determined. Total (TC) total bile acids (TBA) levels feces also measured. Furthermore, activity mRNA...
Abstract Drought stress considered a key restrictive factor for warm-season bermudagrass growth during summers in China. Genotypic variation against drought exists among ( Cynodon sp .), but the selection of highly drought-tolerant germplasm is important its limited water regions and future breeding. Our study aimed to investigate most tolerant thirteen, along latitude longitudinal gradient under well-watered condition. Current included high drought-resistant germplasm, “Tianshui”...
Intermediate wheatgrass (Thinopyrum intermedium (Host) Barkworth & D.R. Dewey), a segmental autoallohexaploid (2n = 6x 42), is not only an important forage crop but also valuable gene reservoir for wheat (Triticum aestivum L.) improvement. Throughout the scientific literature, there continues to be disagreement as origin of different genomes in intermediate wheatgrass. Genotypic data obtained from newly developed EST-SSR primers derived putative progenitor diploid species Pseudoroegneria...
Abstract c‐Myb is a crucial transcription factor that participates in various biological functions; however, its role colorectal cancer ( CRC ) remains poorly investigated. We first analyzed the expression and clinical significance of retrospective cohort enrolling 132 patients. Then, CRISPR /Cas9 technique was used to establish gene KO cell lines. Cellular functional assays vitro vivo were evaluate impact cells. Finally, RNA sequencing investigate potential oncogenic mechanisms regulated by...
The aim of this study is to investigate the dysbiosis characteristics gut microbiota in patients with cerebral infarction (CI) and its clinical implications.Stool samples were collected from 79 CI 98 healthy controls subjected 16S rRNA sequencing identify stool microbes. Altered compositions functions correlation features investigated. Random forest receiver operating characteristic analysis used develop a diagnostic model.Microbiota diversity structure between overall similar. However,...
Aluminium (Al) and fluoride (F) are phytotoxic elements that can inhibit plant growth development. Al3+ F- react with each other to form complexes in the soil which will induce alteration of toxicity single element. However, mechanisms response aluminium induced not very clear. In present study, tall fescue (Festuca arundinacea Schreb) cultivar 'Houndog 5' was treated by 0, 0.4, 4, 20 mg·L-1 Al2(SO4)3 0.5, 5 NaF, respectively. After 25 days treatment, leaf samples were collected for...
Cynodon dactylon (L.) Pers. (commonly known as bermudagrass) is a member of the family Poaceae. It C4 grass that can grow annually and perennially with clone reproduction seed-setting. not only used forage but also weed in many crops. grows along roadsides, barren lands, irrigated seacoasts, where soil salinity major problem. Although bermudagrass distributed worldwide, it shows limited growth under saline conditions. Under salt stress, whole-plant disturbed quality compromised...
Covalent organic frameworks (COFs) are a class of porous crystalline materials with exceptional properties, constructed through covalently linked units. COFs extensively applied in the field biomedicine, particularly context anticancer treatments. First, this review summarizes diverse synthetic methods COFs, including solvothermal synthesis, microwave‐assisted room temperature interface ionothermal techniques, mechanical grinding, and electrochemical methods, their impacts on material's...
"Nanophytovirology" is a potential management approach to combat plant viral diseases. Herein, the impact of foliar application CeO2 nanoparticles (CeO2-NPs) on growth, cell ultrastructure, and physiology alfalfa mosaic virus (AMV)-infected seedlings was explored at different concentrations strategies. In solar greenhouse, 20 mL CeO2-NP suspensions 50, 100, 200, 500 mg/L sprayed onto surface every other day for 9 days. As result, total volume applied per pot 100 mL. It showed that beneficial...