A5058977842- Lung Cancer Diagnosis and Treatment
- Tracheal and airway disorders
- Lung Cancer Treatments and Mutations
- Medical Imaging and Pathology Studies
- Cancer Genomics and Diagnostics
- Voice and Speech Disorders
- Pleural and Pulmonary Diseases
- Ultrasound in Clinical Applications
- Genetic factors in colorectal cancer
- Clinical practice guidelines implementation
- Airway Management and Intubation Techniques
- Global Cancer Incidence and Screening
- Pancreatic and Hepatic Oncology Research
- Myasthenia Gravis and Thymoma
- Radiomics and Machine Learning in Medical Imaging
- Surgical Simulation and Training
- Advances in Oncology and Radiotherapy
- Trauma and Emergency Care Studies
- Pericarditis and Cardiac Tamponade
- Esophageal Cancer Research and Treatment
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular and Diving-Related Complications
- Economic and Financial Impacts of Cancer
- Simulation-Based Education in Healthcare
- Metastasis and carcinoma case studies
Odense University Hospital
2017-2025
Region of Southern Denmark
2019
Svendborg Sygehus
2017
Background Small lung lesions can represent early-stage cancer but are difficult to diagnose. The bronchoscopic approach has the lowest risk of complications; however, diagnostic yield is generally lower compared trans-thoracic biopsies. Cell-free tumor DNA (cftDNA) fragmented stemming from a tumor. CftDNA in form methylated HOXA9 previously been detected bronchial lavage (BL) and proposed as an adjunct conventional biopsies improve yield. aim this study was assess whether HOXA BL could be...
Background and purpose: Multi-disciplinary Team (MDT) meetings are widely regarded as the ‘gold standard’ of lung cancer care. MDTs improve adherence to clinical guidelines for patients. In this study, we describe compare in Denmark Norway by combining national surveys MDT-Metric Observation Decision-making (MDT-MODe) instrument. Materials method: Identical were sent out all MDT centers Danish Lung Cancer Group Norwegian Group. Six centers, three Norway, observed using MDT-MODe Results...
Background: Patients with lung cancer exhibit increased risk of pulmonary embolism (PE). While the contrast phase computed tomography chest in diagnostic work-up suspected malignancy does not allow reliable detection PE, it may be feasible to screen for present PE during endobronchial ultrasound (EBUS) examination. Objectives: The aim this study was establish if screening EBUS patients is and positive findings are predictive PE. Methods: undergoing due suspicion were prospectively enrolled....
Background: Electromagnetic navigation bronchoscopy (ENB) is a relatively new and technically demanding procedure for the guidance of bronchoscopic biopsy to help locate small lung lesions. The results in experienced hands are well described. However, we do not know unexperienced hands—in other words, have no knowledge about how fast you can learn procedure. Aim: aim this study was draw learning curves beginners ENB using Cumulated Sum (CUSUM) analysis, method quantitative evaluation...
Lung cancer is the leading cause of cancer-related death in Denmark and world. The increase CT examinations has led to an detection pulmonary nodules divided into solid subsolid (including ground glass part solid). Risk factors for malignancy include age, smoking, female gender, specific ethnicities. Nodule traits like size, spiculation, upper-lobe location, emphysema correlate with higher risk. Managing these potentially malignant relies on evidence-based guidelines risk stratification....
Trocar pigtail catheter thoracentesis (TPCT) is a common procedure often performed by junior physicians. Simulation-based training may effectively train physicians in the prior to performing it on patients. An assessment tool with solid validity evidence necessary ensure sufficient procedural competence.Our study objectives were (1) collect of for newly developed (Thoracentesis Assessment Tool [ThorAT]) evaluation TPCT performance and (2) establish pass/fail score summative assessment.We...
Biopsying lung tumours with endobronchial access in patients respiratory impairment is challenging. However, fine needle aspiration the ultrasound-endoscope via oesophagus (EUS-B-FNA) makes it possible to obtain tissue samples without entering airways. Safety of EUS-B-FNA these has not earlier been investigated prospectively. Therefore, this study aimed at assessing feasibility and safety from centrally located suspected thoracic malignancy insufficiency. The a prospective observational...
Introduction: The purpose was to assess whether clinical cases of lung cancer are evaluated uniformly at multidisciplinary team (MDT) sites in Denmark.Methods: Sixty detailed case stories with complete imaging were distributed four MDT for evaluation. Conclusions on stage and intent treatment compared Kappa statistics.Results: Agreement regarding single stages had an agreement corresponding a Kappa-value 0.62 (CI: 0.52–0.71). If grouped into localised, locally advanced, disseminated disease...
This study aimed to evaluate the consistency of lung cancer case assessments across multidisciplinary team (MDT) sites in Denmark. The goal was appraise comparability outcomes between hospitals a real-world context. We prepared sixty comprehensive, fictitious stories, complete with images, and distributed them four primary MDT conferences These cases were subsequently evaluated as had they been ordinary patients during regular meetings. compared conclusions on assigned TNM stage proposed...
Abstract Background Flexible bronchoscopy procedures require detailed anatomical knowledge and advanced technical skills. Simulation-based training offers a patient-safe environment that can be more efficient than patient-based training. Physical models are cheaper virtual reality simulators allow trainees to acquainted with the equipment used in clinic. The choice of physical model for depends on local context. aim this study was compare four different flexible Methods BronchoBoy manikin,...
Bronchoscopy has a low risk of complications when diagnosing peripheral lung lesions suspected malignancy, however the procedures do not always determine diagnosis. Several modalities have been invented to improve diagnostic yield, including radial endobronchial ultrasound and electromagnetic navigation, which are currently used by several departments in Denmark. Augmented fluoroscopy, CT-guided bronchoscopy robotic yet available Denmark, but may work-up, as argued this review.
<title>Abstract</title> <bold>Background:</bold> Genomic profiling of advanced solid cancer in patients with no further evidence based standard treatment options is a novel approach to identify potential experimental on specific genomic alterations. Due the expected short survival these timely assessment druggable targets critical minimize risk deterioration during analysis. The primary objective this prospective study evaluate turnaround time for and feasibility clinical investigational...
Genomic profiling of advanced solid cancer in patients with no further evidence based standard treatment options is a novel approach to identify potential experimental on specific genomic alterations. Due the expected short survival these timely assessment druggable targets critical minimize risk deterioration during analysis. The primary objective this prospective study evaluate turnaround time for and clinical investigational procedures. secondary objectives are investigate how often...
Endoscopic ultrasound-guided fine needle aspiration biopsy (EUS-FNA) of the pancreas is performed routinely in many endoscopic centers as part diagnostic set-up for suspected pancreatic cancer. The use transesophageal bronchoscopic (EUS-B-FNA) by pulmonologists has expanded significantly, since it enables effective diagnosis lesions mediastinum and upper abdomen. following case demonstrates safety feasibility EUS-B-FNA a patient with non-small cell lung cancer (NSCLC) mass unknown origin. A...
Diagnosing lung cancer using a flexible bronchoscope is safe procedure with very low risk of complications. Bronchoscopy has high diagnostic accuracy for endobronchial lesions, but it falls short when sampling peripheral lesions. Therefore, several modalities have been invented to guide the lesion and confirm location tumor before tissue sampling. Fluoroscopy used during bronchoscopy provide 2D X-ray image thorax procedure. The tools will be visible, as well lesions if larger than 2.0-2.5...
To biopsy centrally located lung tumors is a challenge, especially in patients with severe respiratory insufficiency. The endobronchial ultrasound guided fine needle aspiration performed through the esophagus (EUS-B-FNA) makes it possible to attain tissue samples without entering airways, but safety insufficiency has not earlier been investigated. Therefore, this study aimed at assessing feasibility and of EUS-B-FNA from lesions suspected cancer <b>Method:</b> indication for tumor existing...
Diagnosing lung cancer using a flexible bronchoscope is safe procedure with very low risk of complications. Bronchoscopy has high diagnostic accuracy for endobronchial lesions, but it falls short when sampling peripheral lesions. Therefore, several modalities have been invented to guide the lesion and confirm location tumor before tissue sampling. Fluoroscopy used during bronchoscopy provide 2D X-ray image thorax procedure. The tools will be visible, as well lesions if larger than 2.0-2.5...
In this case report, we describe the novel use of a permanent indwelling catheter (PiC) in management refractory malignant pericardial effusion (PE). The patient had disseminated lung cancer and was hospitalised repeatedly with circulatory collapse due to PE despite treatments pericardiocentesis (PCC) window (PW). PiC inserted as last resort no complications mediator pericardiodesis (PCD), resulting cease PE. could subsequently be removed, there relapse