Formation of operational neural networks is one the most significant accomplishments human fetal brain growth. Recent advances in functional magnetic resonance imaging (fMRI) have made it possible to obtain information about function during development. Specifically, resting-state fMRI and novel signal covariation approaches opened up a new avenue for non-invasive assessment connectivity (FC) before birth. Early studies this area unearthed insights principles prenatal function. However, very...

Assessing glymphatic function using in-vivo imaging method is of great value for understanding its contribution to major brain diseases. In the present study, we aim validate association between a variety risk factors and potential index function—Diffusion Tensor Image Analysis Along Perivascular Space (ALPS index). We enrolled 142 subjects from communities performed multi-modality magnetic resonance scans. The ALPS was calculated diffusion tensor data, associations with demographic factors,...

To present an unenhanced four-dimensional time-resolved dynamic magnetic resonance (MR) angiography technique with true fast imaging steady-state precession-based spin tagging alternating radiofrequency (STAR), also called TrueSTAR.This study received Institutional Review Board approval and was HIPAA compliant. Informed consent obtained from all subjects. In eight healthy volunteers, the spatial temporal resolution of TrueSTAR were optimized. another six contrast-to-noise ratio (CNR)...

Abstract Purpose: To determine the relationship between calcified cortex and perfusion status of white matter seizure severity in patients with Sturge–Weber Syndrome (SWS), a sporadic neurocutaneous disorder characterized by leptomeningeal angioma, progressive brain ischemia, high incidence seizures using susceptibility weighted imaging (SWI) dynamic contrast‐enhanced (DSC‐PWI). Materials Methods: Fifteen children (ages: 0.9–10 years) unilateral SWS prospectively underwent magnetic resonance...

Purpose To demonstrate the mapping of structures with high susceptibility values, such as sinuses, bones and teeth, using short echo times. Methods Four in vivo datasets were collected a gradient‐echo sequence (TE 1 = 2.5 ms, TE 2 5 ms 3 7.5 ms). Complex division was performed to remove phase offset term generate at ms. Susceptibility maps generated from unwrapped images, geometry‐constrained iterative algorithm, by preserving information extracerebral tissues. The results improved updating...

ABSTRACT Susceptibility‐weighted imaging (SWI) has been widely used in clinical contexts, which the speed of acquisition is frequently a critical issue. In this study, we aim to test feasibility deep learning (DL)‐based reconstruction method for accelerating SWI settings. A total 61 subjects were consecutively enrolled. scans using prospective under‐sampling and DL‐based (acceleration factor = 5, time: 1:46) parallel (PI, acceleration 2, 4:45) acquired from each subject. The utilizes...

Purpose To test the feasibility and consistency of a deep-learning (DL) accelerated QSM method for deep brain nuclei evaluation. Methods Participants were scanned with both parallel imaging (PI)-QSM DL-QSM methods. The PI- scans had identical parameters other than acceleration factors (AF). employed Poisson disk style under-sampling scheme previously developed cascaded CNN based reconstruction model, acquisition time 4:35, 3:15, 2:11 AF 3, 4, 5, respectively. For PI-QSM acquisition, was 2...

ABSTRACT In clinical practice, particularly in neurology assessments, imaging multiparametric MR images with a single‐sequence scan is often limited by either insufficient contrast or the constraints of accelerated techniques. A novel single 3D method, incorporating Wave‐CAIPI and MULTIPLEX technologies named WAMP, has been developed for rapid comprehensive parametric diagnostic applications. Featuring hybrid design that includes wave encoding, CAIPIRINHA sampling pattern, dual time...

We investigated the biophysical mechanism of low-frequency drift in blood-oxygen-level-dependent (BOLD) functional magnetic resonance imaging (fMRI) (0.00-0.01 Hz), by exploring its spatial distribution, dependence on parameters, and relationship with task-induced brain activation. Cardiac respiratory signals were concurrently recorded during MRI scanning subsequently removed from data. It was found that distribution drifts human followed a tissue-specific pattern, greater magnitude gray...

Purpose: To investigate the feasibility of high temporal resolution breast DCE‐MRI using compressed sensing theory. Methods: Two experiments were designed to reference image based (RICS) technique in breast. The first experiment examined capability RICS faithfully reconstruct uptake curves undersampled data sets extracted from fully sampled clinical data. An average approach and an motion estimation compensation (ME/MC) implemented obtain images evaluate their efficacy reducing related...

Purpose To remove the geometry dependence of phase-based susceptibility weighting masks in susceptibility-weighted imaging (SWI) and to improve visualization veins microbleeds. Materials Methods True SWI (tSWI) was generated using susceptibility-based masks. Simulations were used evaluate influence characteristic parameters defining mask. In vivo data from three healthy adult human volunteers compare contrast-to-noise-ratios (CNRs) right septal vein left internal cerebral as measured both...

A quantitative estimate of cerebral blood oxygen saturation is critical importance in the investigation cerebrovascular disease. We aimed to measure change venous (Yv) before and after intake vaso-dynamic agents caffeine acetazolamide with high spatial resolution using susceptibility mapping. Caffeine were administered on separate days five healthy volunteers extraction fraction. The internal streaking artifacts maps reduced by giving an initial value uniformly structure-of-interest, based a...

Magnetic Resonance properties of tissues can be quantified in several respects: relaxation processes, density imaged nuclei, magnetism environmental molecules, etc. In this paper, we propose a new comprehensive approach to obtain 3D high resolution quantitative maps arbitrary body districts, mainly focusing on the brain. The theory presented makes it possible map longitudinal (R1), pure transverse (R2) and free induction decay (R 2 *) rates, along with proton (PD) magnetic susceptibility...

Purpose To achieve simultaneous high‐resolution magnetic resonance angiography and venography (MRAV) imaging in terms of enhanced time‐of‐flight (TOF) susceptibility‐weighted (SWI), with a clear separation arteries veins. Materials Methods A new flow rephase/dephase interleaved double‐echo sequence was introduced that facilitates multiple types contrast, i.e., TOF, SWI, dark blood, single acquisition. nonlinear subtraction (NLS) method is proposed assessed to maximally enhance contrast...

Purpose: To present a fully flow-compensated multiecho gradient echo sequence that can be used for MR angiography (MRA), susceptibility weighted imaging (SWI), and quantitative mapping (QSM) to study the effects of flow acceleration background field gradients on compensation.Methods: The quality compensation was evaluated using data from eight volunteers.The were studied by changing polarities readout in two consecutive scans.The estimate phase errors presence inhomogeneities.SWI QSM...

Background Investigations into the mechanism of diffuse retinal edema in diabetic subjects have been limited by a lack animal models and techniques that co-localized thickness hydration vivo. In this study we test hypothesis previously reported supernormal central on MRI measured experimental retinopathy vivo represents persistent edema. Methodology/Principal Findings age-matched control rats, rats experiencing dilutional hyponatremia (as positive control), whole thickness, intraretinal...

Purpose This study aimed to investigate the prognostic significance of pretreatment dynamic contrast-enhanced (DCE)-MRI parameters concerning tumor response following induction immunochemotherapy and survival outcomes in patients with locally advanced non-small cell lung cancer (NSCLC) who underwent immunotherapy-based multimodal treatments. Material methods Unresectable stage III NSCLC treated by immunochemotherapy, concurrent chemoradiotherapy (CCRT) or without consolidative immunotherapy...

IntroductionThe piriform cortex and cortical amygdala (PCA) the orbitofrontal (OFC) are considered olfactory-related brain regions. This study aims to elucidate normal volumes of PCA OFC each age groups (20.0-70.0 year old), whether decline with increasing diminishing olfactory function. MethodsOne hundred eleven healthy right-handed participants (54 males, 57 females), 20.0 70.0 years were recruited join this after excluding all major causes dysfunction. Volumetric measurements performed...

AIM:To investigate whether liver lobe volume and albumin (ALB) could predict the presence severity of cirrhosis, esophageal varices.METHODS: Seventy-one cirrhotic patients with hepatitis B 21 healthy individuals were enrolled in this study.All participants underwent abdominal enhanced magnetic resonance imaging to measure each volume, biochemical workup for testing ALB Child-Pugh class.All upper gastrointestinal endoscopy show varices.Right (RV), left medial (LMV), lateral (LLV), caudate...

Hepatic cirrhosis is a common pathway of progressive liver destruction from multiple causes. Iron uptake can occur within the hepatic parenchyma or various nodules that form in cirrhotic liver, termed siderotic nodules. Siderotic nodule formation has been shown to correlate with inflammatory activity, and while relationship between malignancy remains unclear, iron distribution known implications for detection hepatocellular carcinoma. We aimed evaluate role abdominal susceptibility-weighted...