- Advanced Polymer Synthesis and Characterization
- Nanoparticle-Based Drug Delivery
- Carbon and Quantum Dots Applications
- Polymer Surface Interaction Studies
- Supercapacitor Materials and Fabrication
- Advancements in Battery Materials
- Advanced Battery Materials and Technologies
- Nanocluster Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- Hydrogels: synthesis, properties, applications
- Conducting polymers and applications
- Nanoplatforms for cancer theranostics
- Luminescence and Fluorescent Materials
- Silk-based biomaterials and applications
- Surface Modification and Superhydrophobicity
- Dendrimers and Hyperbranched Polymers
- Electrospun Nanofibers in Biomedical Applications
- Advanced battery technologies research
- Electrochemical sensors and biosensors
- RNA Interference and Gene Delivery
- Click Chemistry and Applications
- Graphene and Nanomaterials Applications
- MXene and MAX Phase Materials
- Advanced Drug Delivery Systems
- Quantum Dots Synthesis And Properties
Southwest University
2015-2024
Yibin University
2024
State Key Laboratory of Silkworm Genomic Biology
2021
Chongqing University
2018-2020
Georgia State University
2016
Lanzhou University
2011-2014
State Key Laboratory of Applied Organic Chemistry
2011-2014
Ankang University
2009-2012
Northwest Normal University
2009-2010
Combination therapy is an emerging strategy that under intensive preclinical investigation for the treatment of various diseases. CD98 highly overexpressed on surfaces epithelial cells and macrophages in colon tissue with ulcerative colitis (UC), which usually associated mucosal damage inflammation. We previously proved siRNA (siCD98)-induced down-regulation decreased severity UC to a certain extent. In effort further improve therapeutic efficacy, we aim simultaneously deliver siCD98...
Covalent functionalization of azide-modified SiO2 with well-defined, alkyne-terminated poly(N-isopropylacrylamide) was accomplished by the Cu(I)-catalyzed [3 + 2] Huisgen cycloaddition. The RAFT chain transfer agent first synthesized, and then thermoresponsive (PNIPAM) different molecular weights were synthesized NIPAM monomer. polymerization kinetics evolution number-average (Mn), polydispersities (Mw/Mn), monomer conversions investigated. A copper(I)-catalyzed azide–alkyne cycloaddition...
Novel two-dimensional Ti3C2 MXene nanosheets were successfully prepared by etching Al from Ti3AlC2 in LiF/HCl system. In order to further improve the dispersing property and electrical conductivity of nanosheets, Ti3C2/graphene oxide (Ti3C2-GO) nanocomposites synthesized applied for fabrication inkjet-printed hydrogen peroxide (H2O2) sensor. The results electrochemical characterization show that sensor maintains biological activity hemoglobin (Hb) can be practical detection. printed sensors...
A high quantum yield (QY) is the key requirement for implementing carbon dots (CDs) in nearly all applications. In this work, blue emissive N-doped CDs with a QY of 83% and orange 47% were successfully prepared using resorcinol phloroglucin as resources formamide by one-step microwave synthesis, respectively. Formamide not only plays role solvent but also takes part formation CDs. It demonstrated that as-prepared blue- orange-emitting can be uniformly dispersed into glue fabricated CD/glue...
In this work, multifunctional B,N codoped carbon dots (B/N–C-dots) were synthesized from a facile hydrothermal treatment of branched polyethylenimine and 4-formylphenylboronic acid. The obtained B/N–C-dots had very narrow size distribution showed excitation-wavelength-dependent photoluminescence properties with high fluorescence quantum yield (QY) 15.85%. temperature pH (3–13) dual responses. Additionally, the good sensitivity selectivity to Fe3+ detection limit 1.62 μM. What is more,...
A well-defined thermoresponsive poly(ethylene glycol)-block-poly(N-isopropylacrylamide)-block-poly(ε-caprolactone) (PEG43-b-PNIPAM82-b-PCL87) triblock copolymer was synthesized by combination of atom transfer radical polymerization (ATRP), ring-opening (ROP), and click chemistry. The synthesis included the four steps, all structures polymers were determined. can disperse in water at room temperature to form core–shell–corona micelles with hydrophobic PCL block as core, PNIPAM shell,...
Tumor cells show acidic conditions compared with normal cells, which further inspires scientist to build nanocarrier responsive tumor microenvironment (TME) for enhancing therapeutic efficacy. Here, we report a pH-sensitive and biocompatible polyprodrug based on dextran-doxorubicin (DOX) prodrug (DOXDT) enhanced chemotherapy. High-density DOX component was covalently decorated the drug molecules could be effectively released in tissue/cells, improving chemotherapy Specifically, dextran-based...
Orange red-emitting CDs were constructed from 2,3-diaminopyridine and successfully used for visual colorimetry near-infrared cellular imaging.