- Pancreatitis Pathology and Treatment
- Wound Healing and Treatments
- Antimicrobial Peptides and Activities
- Nutrition and Health in Aging
- Retinal Diseases and Treatments
- Nuclear Physics and Applications
- Radiation Detection and Scintillator Technologies
- Ocular Diseases and Behçet’s Syndrome
- Medical Imaging Techniques and Applications
- Body Composition Measurement Techniques
- Electric Power System Optimization
- Hemostasis and retained surgical items
- Ocular Surface and Contact Lens
- Tea Polyphenols and Effects
- Gastrointestinal disorders and treatments
- Viral Infections and Vectors
- Advanced Clustering Algorithms Research
- Medicinal Plants and Neuroprotection
- Smart Grid and Power Systems
- Biochemical and Structural Characterization
- Frailty in Older Adults
- Corneal surgery and disorders
- Rough Sets and Fuzzy Logic
- Appendicitis Diagnosis and Management
- Cardiac and Coronary Surgery Techniques
Shanghai Tenth People's Hospital
2016-2022
Tongji University
2016-2022
Guangdong Ocean University
2019-2022
Chengdu University of Technology
2021-2022
Sun Yat-sen University
2021
Huaqiao University
2020
Guangzhou Center for Disease Control and Prevention
2020
North Sichuan Medical University
2019
Ministry of Education of the People's Republic of China
2018
175th Hospital of People's Liberation Army
2011
Acute pancreatitis (AP) is a serious condition associated with intestinal barrier disruption or inflammation of the pancreatic tissue. Specific microRNAs are involved in pathogenesis AP, during which IL-17-producing CD4+ T helper (Th17) cells accumulate pancreas. In this study, significantly increased levels miR-155 were detected clinical samples from patients and overexpression correlated severe AP (SAP). To identify effect on cell differentiation, we isolated lymphocytes vitro experiments...
ABSTRACT Red cell distribution width (RDW) has been proposed as an early prognosis marker with increased mortality in variety of pathophysiological conditions. We hypothesized that elevated RDW could be used judging the severity acute pancreatitis (AP). retrospectively and prospectively studied 545 72 AP patients, who were admitted to Shanghai Tenth People's Hospital Tongji University, respectively. Compared mild pancreatitis, significantly higher was observed patients moderately severe...
Myopic choroidal neovascularization (CNV) often causes serious damage to central vision. The mechanisms behind it remain unclear.In this study, monocular form deprivation was applied induce high myopia, and 532-nm laser employed CNV in guinea pig. development of measured comprehensively by fundus fluorescein angiography, optical coherence tomography hematoxylin eosin staining. Gene expression detected real-time polymerase chain reaction immunohistochemistry.The proliferation new blood...
Skin wound healing, especially chronic is a common challenging clinical problem. It urgent to broaden the sources of bioactive substances that can safely and efficiently promote skin healing. This study aimed observe effects active peptides (APs) mantle Pinctada martensii on After physicochemical analysis amino acids mass spectrometry APs, effect APs promoting healing was studied through whole cortex model back mice for 18 consecutive days. The results showed consisted polypeptides with...
Previous studies found that both oral and topical administration of enzymatic digestion products < 3 K Da ultrafiltration fractions Pinctada martensii mantle (PMPs) had pro-healing effects. Thus, we further purified them by Sephadex-G25 screened cellular assays to obtain peptides (PMPPs). In this study, explored the mechanism PMPPs on wound healing in vivo, vitro, silico experiments. LC-MS/MS results showed consisted 33 with molecular weights ranging from 758.43 2014.04 Da, characteristic...
Skin wound healing, especially chronic is a common challenging clinical problem. It urgent to broaden the sources of bioactive substances that can safely and efficiently promote skin healing. This study aimed observe effects small molecular peptides (SMPs) mantle Pinctada martensii on After physicochemical analysis amino acids mass spectrometry SMPs, effect SMPs promoting healing was studied through whole cortex model back mice for 18 consecutive days. The results showed consisted...
Background and Objectives: Choroidal neovascularization (CNV) is a common pathologic lesion that occurs in various chorioretinopathy, but very limited published data have reported pediatric patients. This study aimed to investigate the etiologic factors, clinical features, treatment outcomes of choroidal children. Methods: In this study, 33 eyes 30 patients aged 18 years or younger with CNV were included. Comprehensive ophthalmic examination was performed all The demographic profiles,...
The association between obesity and sarcopenia remains controversial. present study was conducted to explore the associations among body mass index (BMI), visceral fat area (VFA), in older people analyze their potential mechanisms. This cross-sectional included 861 community-dwelling Chinese from three regions of China. BMI, VFA, muscle mass, strength, physical performance, composition, metabolic markers were measured. Muscle strength positively correlated with but negatively VFA. Simple...
PURPOSE: To investigate the severity of pancreatitis in lipoprotein lipase (LPL)-deficient hypertriglyceridaemic (HTG) heterozygous mice and to establish an experimental animal model for HTG study. METHODS: LPL-deficient were rescued by somatic gene transfer mated with wild-type mice. The plasma amylase, triglyceride, pathologic changes pancreas compared those assess pancreatitis. In addition, acute (AP) was induced caerulein (50 µg/kg) further assessment. RESULTS: levels amylase...
The electric power industry is regarded as the basic of national economy, which makes it unable to get rid governmentpsilas regulation, well its own technology and economic characteristic. After reforming government pays a good deal attention performance-base regulation has been used in telecommunication successfully can solve low efficiency problem effectively. But method cause contradiction between quality, so people call query efficiency. On this background, after analyzing price cap...
Abstract Intestinal resection and anastomosis are performed in over a million people with various bowel diseases annually. Excessive fibrosis anastomotic site leakage the main complications of surgery, despite great improvements operative technique equipment recent years. In this study, cRGD modified poly(p‐dioxanone‐co‐ l ‐Phe) (PDPA) membranes designed applied intestinal to simultaneously solve two aforementioned complications. is onto PDPA through both physical absorption π–π accumulation...
To prepare and optimize the self-microemulsion co-loaded with tenuifolin β-asarone(TF/ASA-SMEDDS) evaluate its quality. The prescription compositions of TF/ASA-SMEDDS were screened by solubility test, single factor test pseudo-tern-ary phase diagram, prescriptions further optimized Box-Behnken response surface method, drug loading particle size as evaluation indexes. Then was evaluated for emulsified appearance, size, morphology release in vitro. follows: caprylic citrate triglyceride...