- Essential Oils and Antimicrobial Activity
- SARS-CoV-2 and COVID-19 Research
- Genetics, Bioinformatics, and Biomedical Research
- Vaccine Coverage and Hesitancy
- Pomegranate: compositions and health benefits
- Iron Metabolism and Disorders
- Natural Compound Pharmacology Studies
- Pharmacology and Nanomedicine Research
- Phytochemicals and Medicinal Plants
- Phytochemistry and biological activities of Ficus species
- Cardiac Ischemia and Reperfusion
- Cancer-related gene regulation
- Bee Products Chemical Analysis
- Urinary Tract Infections Management
- COVID-19 Pandemic Impacts
- Microbial Metabolism and Applications
- Botanical Research and Applications
- Insect and Pesticide Research
- COVID-19 Impact on Reproduction
- Blood groups and transfusion
- Seed and Plant Biochemistry
- Nitric Oxide and Endothelin Effects
- Ethnobotanical and Medicinal Plants Studies
- Food Science and Nutritional Studies
- Animal Nutrition and Physiology
King Abdulaziz University
2022-2025
Cucumis sativus L., widely cultivated as an edible vegetable. Its seeds are well reputed for cardiovascular preventive properties. However, the mechanisms underlying protection of C. still unidentified. Therefore, this study utilized a metabolomics approach to investigate putative in myocardial infarction (MI) and vitro models vasoconstriction, atrium, invasive blood pressure measurement. Results showed that Cu.EtOH extract vasorelaxant response with potent hypotensive effect normotensive...
Ethnopharmacological relevance Pelargonium zonale (L.) L'Hér. ex Aiton ( P.zonale) is used against various cardiovascular, gastrointestinal and respiratory diseases involving smooth muscles relaxation. It traditionally for the treatment of diarrhea, gastropathy, toothache. Aim study The current was designed to validate its conventional applications, we conducted investigational studies evaluate potential mode operation in management disorders pertaining cardiovascular system, tract, tract...
Epithelial cell transforming 2 (ECT2) is a potential oncogene and number of recent studies have correlated it with the progression several human cancers. Despite this elevated attention for ECT2 in oncology-related reports, there no collective study to combine integrate expression oncogenic behavior panel The current started differential analysis cancerous versus normal tissue. Following that, asked correlation between upregulation tumor stage, grade, metastasis, along its effect on patient...
To evaluate the potential antimicrobial activity, Aloe vera and Opuntia ficus-indica plants were collected from Jeddah, Al Baha, Taif areas of Kingdom Saudi Arabia (SA), their ethanolic extracts screened by gas chromatography mass spectrometry (GC–MS/MS). The di(2-propylpentyl) ester hexadecenoic acid ethyl phthalic most abundant compounds in A. extract, 1-(benzyloxy)-3,5-dinitrobenzene phenol, 5-ethenyl-2-methoxy O. extract. activity aqueous these against seven fungi five pathogenic...
Herbs, as the pomegranate (Punica granatum L.)(P. granatum), has significant chemical constituents with distinct pharmacological properties. These chemicals confer neuroprotective, antioxidant, anticancer, anti-inflammatory, and antibacterial properties to plant. Pomegranate specific components that enable its actions; one of functions extracts is deactivate what called extended spectrum beta-lactamase (ESBL) makes Escherichia coli (E. coli) resistant standard antibiotics. Twenty E. strains...
This study aimed to investigate the fungal growth and diversity in Sabkha marsh. The anti-bacterial properties of isolated fungi were assessed using an agar disk diffusion assay, crude extracts tested for their anticancer activities. Liquid chromatography-mass spectrometry was employed identify active compounds secondary metabolites. In-silico studies conducted predict toxicity, pharmacokinetic properties, safety profiles identified compounds.
Increasing antimicrobial resistance to the action of existing antibiotics has prompted researchers identify new natural molecules with potential. In this study, a green system was developed for biosynthesizing gold nanoparticles (BAuNPs) using sage (Salvia officinalis L.) leaf extract bioconjugated non-toxic, eco-friendly, and biodegradable chitosan, forming chitosan/gold bioconjugates (Chi/BAuNPs). Characterization BAuNPs Chi/BAuNPs conjugates takes place transmission electron microscopy...
Background:Dryopteris ramosa is used as an old treatment for several diseases. D. ramose fronds are eaten to treat gastrointestinal (GIT) issues and antibiotic. However, there a dearth of literature justifying its traditional use. Aims objectives: the current work biological molecular docking studies support usage elucidate ramosa's multitarget mechanism. Materials methods: Bioactive compounds were docked in silico. Force displacement transducers coupled with power lab data gathering system...
The Middle Eastern prevalence of sickle cell anemia, a genetic disorder that affects red blood cells, necessitates additional research. On molecular level, we sought to identify and sort the oral microbiota healthy individuals those with anemia. Furthermore, it is crucial comprehend how changes in makeup impact state Using next-generation sequencing, 16S rRNA amplicon was examined using saliva samples from 36 anemia individuals. These were obtained patients (18 samples) control participants...
On 11th March 2020, the World Health Organization declared COVID-19 as a pandemic. Vaccination programs have advanced greatly in global health period, despite widespread anti-vaccination attitudes and misinformation. Vaccine hesitancy of vaccine is currently major issue Saudi Arabia. This cross-sectional study was carried out from June 25, 2021 to October order investigate knowledge levels acceptance among Saudi’s nationals. The data collected through close-ended structured...
S TAPHYLOCOCCUS aureus can enter the bloodstream, leading to health complications such as sepsis, arthritis, endocarditis, and pneumonia.This study screened for impact of six replication genes cos phage 12 (φ12) on evolution transfer S. pathogenicity islands (SaPIbov5).An overnight culture strain RN4220 diluted with fresh TSB was used in bacteriophage φ12 titering assay.Phage-point mutagenesis achieved using pMAD vector, which facilitates homologous recombination a two-step process.Finally,...
Introduction: In a previous study, the presence of Aspergillus species in high-salt soil was investigated. However, it hypothesized that addition protein source to could reveal other fungal species. This study aimed test this hypothesis by repeating methodology used but with inclusion source.Materials and methods: The ribosomal DNA (ITS) region sequenced identify isolate. results showed isolate belonged different genus within species, specifically sydowii. strain named WIS recorded gene bank...
On 11th March 2020, the World Health Organization (WHO) declared coronavirus disease (COVID-19) as a pandemic. The is caused by severe acute respiratory syndrome 2 (SARS-CoV-2). As of 17 June 2022, SARS-CoV-2 has infected over 535,248,141 people, with 6,313,229 deaths. Due to devastating effect COVID-19, achieving herd immunity prevent onward transmission crucial. Although obtaining against COVID-19 through natural infection theoretically possible but would place enormous burden on...