A5063331142- Food Allergy and Anaphylaxis Research
- Eosinophilic Esophagitis
- Skin and Cellular Biology Research
- Vitamin D Research Studies
- Celiac Disease Research and Management
- Allergic Rhinitis and Sensitization
- Human Health and Disease
- Dermatology and Skin Diseases
- Asthma and respiratory diseases
- Vitamin C and Antioxidants Research
- Viral gastroenteritis research and epidemiology
- Neonatal skin health care
- Cardiac Structural Anomalies and Repair
- Prion Diseases and Protein Misfolding
- Pulmonary Hypertension Research and Treatments
- Exercise and Physiological Responses
- Food Safety and Hygiene
- Esophageal and GI Pathology
- Eating Disorders and Behaviors
- COVID-19 Clinical Research Studies
- Cardiovascular Issues in Pregnancy
- Obesity, Physical Activity, Diet
- Child Nutrition and Feeding Issues
- Cardiac Valve Diseases and Treatments
- Parasitic Diseases Research and Treatment
Scientific Center of Children's Health
2022-2025
Ministry of Health of the Russian Federation
2022-2025
Center for Children
2021-2024
The First Republican Clinical Hospital of the Ministry of Health of the Udmurt Republic
2013
Introduction. Case reports of Food Protein-Induced Enterocolitis Syndrome (FPIES) associated with buckwheat consumption are quite rare. However, over the course 3 years at Federal State Autonomous Institution “National Medical Research Center for Children’s Health” Ministry Health Russia, we observed patients who can be considered cases this rare pathology. Presentation clinical case. The article briefly describes Syndrome, porridge, in three — 11 months, 7 and 7.5 old. All featured an acute...
Введение. Данный обзор представляет собой анализ особенностей козьего молока как сырья для производства смесей искусственного вскармливания. В настоящее время все более широкое распространение получают детские смеси на основе молока. Несмотря то что состав детских регламентирован по всем компонентам, исходное сырье не может влиять особенности конечного продукта. отличие от коровьего молока, продуцируемого мерокриновым типом секреции, козье, и женское молоко, характеризуется апокриновым...
Relevance of topic. The course atopic dermatitis complicated by food allergies, as well the use an elimination diet, can significantly worsen patient’s quality life and affect his eating behavior. Aim study was to assess indicators behavior in children with severe allergies. Methods. This included age 4–13 years 11 months, hospitalized Dermatology Laser Surgery department National Medical Research Center Children’s Health from September 2021 May 2022. Anthropometric indices, index influence...
Early diagnostics for parasitic diseases of musculoskeletal system is rather challenging due to rare occurrence described pathology.The authors review a clinical case female patient, 49 years old, with dirofilariasis tendinous sheath extensor pollicis longus. The patient was admitted hospital diagnosis dorsal hand ganglion cyst. Correct made only after parasite extraction during surgical procedure. discuss issues differential such disease as well ganglion. Diagnosis can be confirmed by...
Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease characterized by esophageal dysfunction due to prolonged eosinophilic infiltration of tissues. In recent years, there has been tendency increase the prevalence EoE, which may lead an in detection strictures children. Aim: determine clinical features phenotype with outcome stenosis Materials and methods. Seventy children diagnosed EoE were examined, 9 (12.86%) them had stenosis. The average age manifestation was 6.17 years....
Introduction. Despite active research into the mechanisms of food allergies (FA), main approach to managing patients with this condition remains complete exclusion causative allergens from diet for a certain period. At same time, question timely reintroduction excluded triggers is frequently raised, which important both maintaining oral tolerance and reducing negative effects long-term elimination diets, such as nutritional eating behavior disorders, well financial burdens on families....
Chicken egg is among the most important sources of allergens. Sensitization to them often manifests as food allergy (FA), and/or atopic dermatitis (AD). Immunogenic substances a chicken are present in both white and yolk. The purpose our work was compare frequency intensity IgE responses various components children, depending on their age gender. We examined 3070 children with symptoms allergies dermatitis, analyzed allergens extract (f1) yolk (f75), taking into account gender children....
Introduction. I nherited epidermolysis bullosa belongs to the group of severe rare hereditary mechanobullous diseases. Often, skin pathological process is difficult treat, which leads a decrease in quality life such patients. The mechanism development transcutaneous sensitization this category patients not excluded. This issue remains very relevant area for study, given characteristic nutritional deficiency and difficulties that arise formation diet. aim: assess frequency occurrence...
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Eosinophilic esophagitis (EoE) is a multifactorial disease characterized by variable clinical manifestations and varying responses to therapy, especially in pediatric patients. The purpose of this research was analyze the results EoE various treatment methods children. Materials used: single-center retrospective cohort study conducted 2020-2023 that included patients from 6 y/o 17 years 11 months old whose condition assessed when verifying diagnosis after prescribing therapy at least once....
In recent years, the challenge of control and maintenance nutritional status in patients on an elimination diet for food allergies has got a lot attention. Due to possibility long-term important groups without adequate replacement, high efficiency this treatment method been linked with risk deficiency, impaired physical growth, eating behavior disorders children. This review takes into account growth children due insufficient intake micronutrients (vitamins, fatty acids), as well such...
Food allergy is a potentially life-threatening condition without approved pathogenetic treatments other than eliminating the causal allergen and relief of acute allergic conditions. Immunoglobulin G-mediated form food remains serious growing problem worldwide. Its prevalence steadily increasing severe psychosocial economic burden for patients their families. Cow-based milk products are important components childs diet, which introduced at first year life, can cause reactions. The traditional...
Aim. To assess the efficacy of regional system multidisciplinary care in pulmonary hypertension (PH). Material and methods . In a single-center, pro retrospective cohort study, 2001-2015, epidemiological characteristics yearly mortality from PH were assessed created late 1990s multiple management Udmurt Republic. According to specific drug therapy tactics, there three periods observation: 2001-2005 patients received, by indication calcium channel blockers supportive therapy; 2006-2010...
Relevance . Dairy-free diet is the basis of cow’s milk allergy (CMA) patient’s management. Duration individual, but some children don’t develop tolerance. The aim study was to investigate health and growth indices in with CMA depending on tolerance development by age five. Materials methods. 153 from 1 18 months diagnosed were included prospective (76.5% IgE-mediated form). determined after 6–12 a milk-free at 5 using an open challenge test. Anthropometry (Anthro Plus), levels specific IgE...
BACKGROUND: International studies have shown that egg allergy is one of the main causes IgE-mediated food allergies in children. THIS STUDY AIMED TO analyze frequency and rate sensitization to white Russian children, depending on sex age. MATERIALS AND METHODS: Anti-egg white-specific IgE antibodies were measured children with symptoms allergy, such as nausea, vomiting, stool disorder developing after eating, mucosal edema, upper respiratory tract urticaria, exacerbation eczema (4981...
Relevance of topic . Atopic dermatitis is a wide-spread skin disease that can significantly reduce patient’s quality life. Many authors around the globe conduct research to find correlation between atopic detmatitis in children, their growth, development allergic comorbidities (food allergy particular) and elimination diet prescription. Aim study To estimate growth indices nutritional status children with severe on diet. Methods This included age 0-17 years 11 months, hospitalized...
Purpose: Successful surgical intervention in valvular heart disease has been shown to prolong and improve quality of life. We aimed evaluate postoperative health-related life (HRQoL) patients following trimetazidine therapy. Methods: 120 [aged 53.2±2.1 years, 60% males] 2–4 weeks after conventional aortic (n=64) mitral (n=56) valve replacement by mechanical prostheses (40% due degenerative, 35% rheumatic, 10% myxomatous, 8.3% congenital diseases 6.7% infectious endocarditis) were randomized...
Number of children with eosinophilic esophagitis (EoE) observed has recently increased, therefore significant experience been gained in the diagnosis and treatment this disease. However, systemic data from Russian pediatric centers’ registers that would summarize signs disease childhood not published as yet. The purpose research was to study demographic, clinical, endoscopic morphological features EoE form unified register patients on basis a single yet multidisciplinary hospital. Materials...
BACKGROUND: Inherited epidermolysis bullosa is a severe orphan hereditary disease with predominant lesion of the skin and mucous membranes. The study comorbid background, including food allergies, remains an urgent issue, given difficulties that often arise in treatment formation diet this category patients.
 AIM: to assess frequency nature allergies children inherited bullosa.
 MATERIALS AND METHODS: An open single-center randomized observational retrospective prospective included...
Inherited epidermolysis bullosa includes a spectrum of rare genodermatoses characterized by dysfunction the skin barrier, high permeability, and therefore risks sensitization to most common allergens. The aim . To assess prevalence food allergies immunological features allergy cow’s milk proteins among large cohort children with inherited bullosa. Materials methods He study was conducted participation small different age groups suffering from congenital Children were necessarily consulted an...
Violation of the formation tolerance to food proteins remains a widespread phenomenon. The review examines immune mechanisms and factors influencing development tolerance. age aspects predictors various forms allergy are analyzed. advantages passive active management children with persistent discussed.
The important role of the micronutrient status body for formation an adequate immune response, including to respiratory viruses, is currently beyond doubt. In connection with beginning pandemic caused by SARS-CoV-2, numerous publications have appeared on supposedly protective effect many micronutrients, especially vitamin D in relation prevention COVID-19 disease. Later, results most studies confirmed this assumption. From 2020 early 2022, there were published 17 analytical reviews and...