- Esophageal and GI Pathology
- Gallbladder and Bile Duct Disorders
- Respiratory Support and Mechanisms
- Gastric Cancer Management and Outcomes
- Gastrointestinal Bleeding Diagnosis and Treatment
- Abdominal vascular conditions and treatments
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal Tumor Research and Treatment
- Airway Management and Intubation Techniques
- Metastasis and carcinoma case studies
- Respiratory and Cough-Related Research
- Pediatric Hepatobiliary Diseases and Treatments
- Gastrointestinal disorders and treatments
- Gastroesophageal reflux and treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Pediatric Pain Management Techniques
- Neuroendocrine Tumor Research Advances
- Pancreatitis Pathology and Treatment
- Anesthesia and Pain Management
- Neuroscience of respiration and sleep
- Obstructive Sleep Apnea Research
- Anesthesia and Sedative Agents
- Aortic aneurysm repair treatments
- Dysphagia Assessment and Management
- Vasculitis and related conditions
Shonan Kamakura General Hospital
2019-2025
Weatherford College
2023
Kubota (Japan)
2022-2023
National Kyushu Medical Center
2000-2016
Chiba University
1993-2009
Medical Center Hospital
2000
Kobe University
2000
Health First
1997
Tokyo National Hospital
1989-1993
National Cancer Center
1988-1993
Colonic diverticular bleeding is a leading cause of lower gastrointestinal bleeding, accounting for the increasing hospitalization rate in Japan. Although over-the-scope clips (OTSCs) have demonstrated favorable outcomes as an initial hemostatic method, their effectiveness rescue therapy after rebleeding from primary endoscopic hemostasis remains unclear. This study describes four patients with colonic who underwent OTSC procedure using standard methods. Immediate was achieved all cases;...
The effects of constant positive airway pressure applied via a nose mask through the nares (nasal CPAP) on swallowing reflex were studied in eight adult humans. was induced by bolus injections small amount distilled water (0.5 ml) into pharynx at four different values endexpiratory (0,5,10, and 15 cm H2O or continuous infusion (3 ml/min) two (0 CPAP). latency response from time injection to occurrence first swallow as well number swallows elicited during period 10 s immediately following...
Cisplatin (CDDP) combination chemotherapy is widely administered to patients with advanced lung cancer. The dose depends on multiple factors, including whether the tumor non-small-cell cancer (NSCLC) or small-cell (SCLC). Although efficacy limited by cisplatin-induced nephrotoxicity (CIN), little known about risk factors for this complication. aim of study was identify CIN in cancer, both NSCLC and SCLC. We retrospectively reviewed clinical data 148 who underwent initial CDDP ≥50 mg/m2 per...
To prevent the increase of resistant bacteria, it is important to minimize use antimicrobial agents. Studies have found that administration for ≤3 days after successful endoscopic retrograde cholangiopancreatography (ERCP) appropriate. Therefore, present study aimed verify if agents can be further shortened ≤2 ERCP. We divided 390 patients with mild and moderate cholangitis who underwent technically ERCP from January 2018 June 2020 had positive blood or bile cultures into two groups:...
Bleeding can be a serious adverse event of endoscopic sphincterotomy (EST). However, the risk EST bleeding between direct oral anticoagulant (DOAC) users and those who received no antithrombotic agents has not been clarified. This study analyzed factors for after in patients on DOAC evaluated Japan Gastroenterological Endoscopy Society (JGES) guidelines gastroenterological endoscopy undergoing treatment.We retrospectively 524 treated with or drug from May 2016 to August 2019. We investigated...
Objectives Considering that pathogens resistant to initial antibiotic therapies for cholangitis can affect mortality rates, appropriate empiric therapy is important. However, evidence regarding the influence of antibiotics in patients with who have undergone early endoscopic retrograde cholangiopancreatography (ERCP) limited, and conditions several cases improve ERCP even when are detected on time. Therefore, this study aimed assess course undergoing ERCP. Materials methods Patients (n=266)...
Splenic diseases may be caused by infections and can either malignant, such as lymphoma lung cancer, or benign, hemangioma. In some cases, diagnostic uncertainty of imaging persists, image-guided splenic needle biopsy is a useful tool to avoid the disadvantages incorrect diagnosis, including performing unnecessary splenectomy not giving necessary treatment. biopsies divided into ultrasound-guided, computed tomography (CT)-guided fine-needle aspiration, core (CNB). However, few studies have...
Abstract Background Upper gastrointestinal (GI) bleeding is the most important presentation of an aorto-duodenal fistula (ADF). Early diagnosis difficult, and disease associated with high mortality. The present study aimed to examine clinical endoscopic characteristics ADF in eight patients who presented our hospital. We also sought clarify diagnostic approach towards disease. Methods examined endoscopic/computed tomography (CT) were definitively diagnosed this condition a 12-year period at...
Background: Percutaneous intraspinal navigation is a new procedure that enables visualization of the central nervous system using lumbar puncture technique. Past research shows promising potential, but limited by damage to expensive fiberscopes due sharp angle manipulation at L3-L4. Our objective in this study analyse feasibility novel access through sacral hiatus eliminate problem. Methods: We retrospectively reviewed computed tomography images sacrum 132 subjects, which nine were excluded...
We studied dynamic cerebrovascular responses in eight healthy humans during repetitive stepwise upward tilt (SUT) and downward (SDT) maneuvers between supine 70° standing at intervals of 60 s. Mean cerebral blood flow velocity (FV MCA ) was measured the middle artery (MCA) with transcranial Doppler ultrasonography. arterial pressure (ABP) via radial adjusted level (ABP ). Cerebral critical closing (P CC estimated from systolic-diastolic relationship FV ABP . minus P considered perfusion...
We herein describe an 82-year-old patient who presented with proteinuria and systemic edema. He was diagnosed minimal change disease (MCD) found to have stage III pancreatic cancer. could not undergo surgical resection due invasion the celiac artery he thus treated chemotherapy. After a month of chemotherapy, his improved normal level. two months computed tomography indicated partial response therapy. MCD can occur as paraneoplastic syndrome in patients malignant disease, chemotherapy be...
生理学的に呼吸困難と疼痛には多くの点で共通することが多く, 疼痛の生理学に精通している麻酔科医には呼吸困難は比較的研究しやすいテーマと思われる. 呼吸困難は異常な呼吸感覚であり, その発生にはいくつかの感覚受容器の働きが重要である. 呼吸困難の発生機序としては, 感覚受容器からの求心性入力と中枢からの運動出力とに解離が存在する場合に呼吸困難感が発生するという考え方, すなわち中枢-末梢ミスマッチ説が最も有力である. さらに, 最近の画像分析研究で呼吸困難感発生には疼痛発生と同様に帯状回 (Gyrus cinguli) , 島 (Insula) など情動に関連した大脳部位の重要性が指摘されている. がん患者の呼吸困難の治療に関しては, 疼痛と比較して選択できる薬物や方法の幅はきわめて狭く, 今後の研究が必要となっている.
<b><i>Introduction:</i></b> Cold snare polypectomy (CSP) is a procedure with low risk of complications. Here, we present our experience rare case submucosal abscess following CSP in an immunosuppressed patient. <b><i>Case Presentation:</i></b> Seventy-eight-year-old man underwent CSP, developing fever, chills, and right lower abdominal pain 8 days later. Ultrasound computed tomography revealed wall thickening the ascending colon, presenting as...
Duodenal Brunner's gland hyperplasia (BGH) is a therapeutic target when complications such as bleeding or gastrointestinal obstruction occur malignancy cannot be ruled out. Herein, we present case of large BGH treated with endoscopic mucosal resection (EMR).
腹膜透析(PD)関連腹膜炎の原因はタッチコンタミネーションや出口部感染が多い.今回進行大腸癌からのbacterial translocationが原因と考えられた稀な症例を経験したため報告する.78歳女性,原疾患不明の慢性腎臓病(CKD)に対し4年前に当院でPD導入した.排液混濁と腹痛で受診し,PD関連腹膜炎の診断で入院した.セフタジジム(CAZ)の腹腔内投与,バンコマイシン(VCM)の静脈内投与を開始し,腹痛・排液細胞数は改善傾向であった.排液培養から検出された大腸菌は抗菌薬感受性良好であり第6病日にCAZをセファゾリン(CEZ)に変更した.しかし第9病日に排液細胞数が再上昇したため,腸管内の器質的病変からのbacterial translocationを考慮し,下部消化管内視鏡を行った.横行結腸に2型(潰瘍限局型)腫瘍を認め,大腸癌によるbacterial translocationと考えられた.PD関連腹膜炎治療中に排液細胞数が再上昇する場合や,PD関連腹膜炎を繰り返す際には,大腸癌も念頭に置き精査する必要がある.
Pancreaticoduodenectomy (PD) is the standard treatment for duodenal cancers suspected of submucosal invasion. Pathological diagnosis from biopsy samples has some limitations. We present case a man in his 70s with bile duct dilation and parapapillary cancer. Given uncertainty biopsy, endoscopic dissection (ESD) was performed as minimally invasive diagnostic alternative to PD. Histological revealed an adenomyoma high-grade adenoma, underscoring efficacy ESD accurately diagnosing periampullary...