- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Helicobacter pylori-related gastroenterology studies
- Gallbladder and Bile Duct Disorders
- Abdominal vascular conditions and treatments
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Neuroendocrine Tumor Research Advances
- Eosinophilic Esophagitis
- Medical Imaging and Pathology Studies
- Infectious Aortic and Vascular Conditions
- Urticaria and Related Conditions
- Aortic aneurysm repair treatments
- Liver Disease and Transplantation
- Gout, Hyperuricemia, Uric Acid
- Veterinary medicine and infectious diseases
- Pediatric Hepatobiliary Diseases and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Pancreatitis Pathology and Treatment
- Microscopic Colitis
- Potassium and Related Disorders
Shonan Kamakura General Hospital
2017-2025
Kubota (Japan)
2023
Weatherford College
2023
Kitasato University
2022
University Gastroenterology
2022
Iwate Medical University
2018
Tokushima University
2012
Hyogo Medical University
2011
Colonic diverticular bleeding is a leading cause of lower gastrointestinal bleeding, accounting for the increasing hospitalization rate in Japan. Although over-the-scope clips (OTSCs) have demonstrated favorable outcomes as an initial hemostatic method, their effectiveness rescue therapy after rebleeding from primary endoscopic hemostasis remains unclear. This study describes four patients with colonic who underwent OTSC procedure using standard methods. Immediate was achieved all cases;...
Background and Objectives Limited information exists regarding beneficial effects of Helicobacter pylori . To examine the effect in advanced gastric cancer, we compared survival for patients treated with surgery‐only or adjuvant chemotherapy on basis H. infection status. Methods A cohort 491 who underwent R0 resection locally cancer between 2000 2009 at 12 institutions northern Japan was included. status, assessed from paraffin‐embedded formalin‐fixed samples. Overall (OS) disease‐free (DFS)...
To prevent the increase of resistant bacteria, it is important to minimize use antimicrobial agents. Studies have found that administration for ≤3 days after successful endoscopic retrograde cholangiopancreatography (ERCP) appropriate. Therefore, present study aimed verify if agents can be further shortened ≤2 ERCP. We divided 390 patients with mild and moderate cholangitis who underwent technically ERCP from January 2018 June 2020 had positive blood or bile cultures into two groups:...
Splenic diseases may be caused by infections and can either malignant, such as lymphoma lung cancer, or benign, hemangioma. In some cases, diagnostic uncertainty of imaging persists, image-guided splenic needle biopsy is a useful tool to avoid the disadvantages incorrect diagnosis, including performing unnecessary splenectomy not giving necessary treatment. biopsies divided into ultrasound-guided, computed tomography (CT)-guided fine-needle aspiration, core (CNB). However, few studies have...
Abstract Background Upper gastrointestinal (GI) bleeding is the most important presentation of an aorto-duodenal fistula (ADF). Early diagnosis difficult, and disease associated with high mortality. The present study aimed to examine clinical endoscopic characteristics ADF in eight patients who presented our hospital. We also sought clarify diagnostic approach towards disease. Methods examined endoscopic/computed tomography (CT) were definitively diagnosed this condition a 12-year period at...
Background . While heat and moisture exchangers (HMEs) have been increasingly used for humidification during mechanical ventilation, the efficacy of pediatric HMEs has not yet fully evaluated. Methods We tested ten when mechanically ventilating a model lung at respiratory rates 20 30 breaths/min pressure control 10, 15, cmH 2 O. The expiratory gas passed through heated humidifier. created two leakage: 3.2 L/min (small) 5.1 (large) was 10 measured absolute humidity (AH) Y-piece. Results...
We treated two patients with male infertility due to 21-hydroxylase deficiency. Endocrinologic examinations disclosed low levels of LH and FSH, elevated ACTH 17-OH-progesterone in both. In addition, a small testicular tumor was found Case 1, which disappeared after adrenal replacement. Suppressed gonadotropin caused by increased androgen seemed underlie the sperm dysfunction these patients. Dexamethasone then clomiphene were administered dexamethasone 2. Spermatogenesis somewhat improved...
Although hyperuricemia is suggested to increase allantoin production in both pro- and antioxidant manners, it remains undetermined whether increases the serum concentration of allantoin. In addition, since uric acid has actions, a decrease may have an effect on pro-oxidant-antioxidant balance.To examine correlated with urate, we measured those levels as well other parameters 63 healthy subjects. determine reactive oxygen species (ROS) biomarkers, 8-hydroxy deoxyguanosine 15-F2t-isoprostane,...
The effects of tofisopam, a GABA-receptor agonist, following oral administration (300mg) with and without allopurinol pretreatment on the plasma concentration renal transport uric acid oxypurinol were investigated in 5 healthy subjects. Fractional urinary excretions both significantly increased at 2-3 hours after tofisopam (559% 459%, respectively), while was decreased (36%) 2.5 hours, suggesting that affects metabolism via tubular system. hypouricemic effect comparable to or greater than...
Abstract Rationale: Simple liver cysts are common, and usually benign asymptomatic, requiring little to no treatment. Liver with biliary communication, however, rare require effective treatment avoid recurrence. Patient concerns: A 70-year-old woman breast cancer visited our hospital for Physical examination revealed abdominal distension bilateral lower leg edema. Diagnosis: Abdominal contrast-enhanced computed tomography a giant cyst, inducing inferior vena cava compression that was causing...
Duodenal Brunner's gland hyperplasia (BGH) is a therapeutic target when complications such as bleeding or gastrointestinal obstruction occur malignancy cannot be ruled out. Herein, we present case of large BGH treated with endoscopic mucosal resection (EMR).
An 80-year-old man presented to our hospital with anorexia. esophagogastroduodenoscopy revealed a type 1 tumor occupying the esophagus and diagnosis of esophageal carcinosarcoma was made. A palliative irradiation planned, but as invasion into thoracic aorta suspected on enhanced computed tomography, endovascular aortic repair (TEVAR) performed prevent aorto-esophageal fistula (AEF). AEF has been reported occur in 14.6% patients during after chemoradiotherapy for cancer invading is fatal....
Pancreaticoduodenectomy (PD) is the standard treatment for duodenal cancers suspected of submucosal invasion. Pathological diagnosis from biopsy samples has some limitations. We present case a man in his 70s with bile duct dilation and parapapillary cancer. Given uncertainty biopsy, endoscopic dissection (ESD) was performed as minimally invasive diagnostic alternative to PD. Histological revealed an adenomyoma high-grade adenoma, underscoring efficacy ESD accurately diagnosing periampullary...
Helicobacter pylori ( H ) eradication is expected to effectively prevent gastric cancer (GC). However, GC cases may occur even longer than 10 years after (L10AE). Moreover, the associated factors and characteristics are unknown. In this retrospective, single-center study conducted between 2017 2022, patients with diagnosed were enrolled categorized into groups according whether they shorter (S10AE) or L10AE. Patients also depth of invasion. Clinical data, pathological risk analyzed using...
<b><i>Introduction:</i></b> Cold snare polypectomy (CSP) is a procedure with low risk of complications. Here, we present our experience rare case submucosal abscess following CSP in an immunosuppressed patient. <b><i>Case Presentation:</i></b> Seventy-eight-year-old man underwent CSP, developing fever, chills, and right lower abdominal pain 8 days later. Ultrasound computed tomography revealed wall thickening the ascending colon, presenting as...
Key Clinical Message Embolization with IMPEDE embolization plug cannot be confirmed on site. Therefore, we propose that the diameter of device selected up to 50% larger than vein prevent failure and recanalization. Abstract Balloon‐occluded retrograde transvenous obliteration percutaneous transhepatic (PTO) are performed for treating sporadic gastric varices. has been recently developed these procedures; however, no studies have reported its use. This is first report use in PTO
Parechovirus A type 3 (PeVA3) is most commonly transmitted to adults from children. Although PeVA3 infection rarely diagnosed, as the symptoms are generally mild and self-limiting, this has been associated with epidemic myalgia in Japan. The patient, a 37-year-old man, presented severe generalized myalgia, inability open his mouth, orchitis, which resolved over period of 10 days. All members family were thought have infected during visit an amusement park. source mouth atypical, acute muscle...
The European Society of Gastrointestinal Endoscopy recommends temporary esophageal stenting for the treatment benign leaks, but there is no consensus on duration stent placement [1]. Prolonged can result in tissue hyperplasia that makes removal difficult, and forcible cause perforation requiring surgery [2]. There are reports a stent-in-stent approach enables [3], it involves cost another stent. Argon plasma coagulation (APC) an endoscopic submucosal dissection (ESD) knife used to resect...
Ischemic gastritis is a clinically rare and highly fatal disease that occurs when the hemodynamics of patient with vascular risk disrupted. Early diagnosis treatment are possible only upper endoscopy after symptom appearance. We report seven cases ischemic its clinical features, prognosis, indicators may help in early detection.Of patients, six had five died within 2 wk diagnosis. Their symptoms included hematemesis hypotension. Although surgery choice for radical treatment, not all patients...
Current guidelines recommend colonoscopy within 24 h for acute lower gastrointestinal bleeding; however, the evidence in support colonic diverticular hemorrhage (CDH) indications remains insufficient.To investigate effectiveness of early on length hospital stay CDH patients.We conducted a single-center retrospective cohort study. Patients who underwent presentation (early group) were compared with those beyond (elective group). The primary outcome was stay, and secondary outcomes...
Abstract Chronic ischemic gastritis (CIG) requires early diagnosis and treatment as complications of thromboembolism can be fatal. Although computed tomography (CT) is useful in the CIG, it difficult to diagnose from a patient's history, endoscopic findings, tissue biopsy. Identification key findings that motivate an important issue. We report case CIG diagnosed by white patches mucosa over time. A 63‐year‐old man presented with epigastric pain. He had history repeated gastric ulcers...