A5040578544- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Pediatric Hepatobiliary Diseases and Treatments
- Esophageal and GI Pathology
- Pancreatitis Pathology and Treatment
- Biliary and Gastrointestinal Fistulas
- Liver Disease and Transplantation
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Gastric Cancer Management and Outcomes
- Amoebic Infections and Treatments
- Neuroendocrine Tumor Research Advances
- Gastrointestinal disorders and treatments
- Abdominal vascular conditions and treatments
- Hepatitis Viruses Studies and Epidemiology
- Vascular Anomalies and Treatments
- Eosinophilic Esophagitis
- Appendicitis Diagnosis and Management
- Gastrointestinal Tumor Research and Treatment
- Viral gastroenteritis research and epidemiology
- Liver Disease Diagnosis and Treatment
- Liver Diseases and Immunity
- Potassium and Related Disorders
- Intraperitoneal and Appendiceal Malignancies
Tokyo Medical University
2016-2025
Tokyo Medical University Hospital
2025
Shonan Kamakura General Hospital
2021-2024
Kubota (Japan)
2023
Weatherford College
2023
Background: Biliary tract cancers (BTCs), including gallbladder and bile duct cancers, have a poor prognosis. Recent advances in chemotherapy, such as using targeted drugs for specific gene mutations, improved outcomes. Gemcitabine plus cisplatin chemotherapy has been the standard of care primary treatment BTCs, but secondary had not established until recently. In recent years, durvalumab gemcitabine (GCD) is emerging promising regimen, although more evidence needed its effectiveness....
Background: Early detection of pancreatic cancer using existing tumor markers is challenging, and novel biomarkers are needed. Apolipoprotein A2 (APOA2), which not directly produced by tumors, may help detect through mechanisms distinct from carbohydrate antigen 19-9 (CA 19-9). This study aimed to evaluate the diagnostic performance APOA2-isoform (APOA2-i) Index in patients with cancer. Methods: Serum levels APOA2-i CA were measured 76 (Stage 0, n = 5; I, 4; II, 15; III, 19; IV, 33) 98...
Abstract Background and study aims Although the number of resistant bacteria tends to increase with prolonged antimicrobial therapy, no studies have examined relationship between duration therapy in acute cholangitis. We hypothesized that short-term administration agents cholangitis would suppress bacterial resistance. Patients methods This was a single-center, retrospective, observational patients admitted January 2018 June 2020 who met following criteria: successful biliary drainage,...
Abstract Background Endoscopic ultrasound‐guided tissue acquisition is vital for diagnosing pancreatic and peridigestive tract lesions. A new three‐prong asymmetry tip needle has been developed this procedure. In study, we retrospectively assessed the diagnostic ability, collection volume, procedural adverse events of solid pancreatic, subepithelial, other organ Methods We analyzed data 58 consecutive patients who underwent endoscopic using a between August 2022 April 2023 at single care...
To prevent the increase of resistant bacteria, it is important to minimize use antimicrobial agents. Studies have found that administration for ≤3 days after successful endoscopic retrograde cholangiopancreatography (ERCP) appropriate. Therefore, present study aimed verify if agents can be further shortened ≤2 ERCP. We divided 390 patients with mild and moderate cholangitis who underwent technically ERCP from January 2018 June 2020 had positive blood or bile cultures into two groups:...
The role of computed tomography (CT) in the initial diagnosis pancreatic cancer (PC) is well-known. CT reports made by radiologists are important as not all patients with PC examined specialists; however, some cases identified based on reports. Diagnosis via imaging sometimes difficult, and diagnostic rate other diseases can vary across radiologists. This study aimed to examine details difficulties. single-centered, retrospective collected clinical data 198 histologically diagnosed between...
Vanishing bile duct syndrome (VBDS) is characterized by degeneration and necrosis, which result in loss stasis. A 70-year-old man had malaise after receiving celecoxib. Laboratory tests revealed elevated hepatobiliary enzymes. His condition worsened without response to medical treatment, he was transferred our hospital. liver biopsy severe injury mild cholestasis. He diagnosed with celecoxib-induced VBDS underwent bilirubin adsorption therapy. However, his continued deteriorate, died. An...
Splenic diseases may be caused by infections and can either malignant, such as lymphoma lung cancer, or benign, hemangioma. In some cases, diagnostic uncertainty of imaging persists, image-guided splenic needle biopsy is a useful tool to avoid the disadvantages incorrect diagnosis, including performing unnecessary splenectomy not giving necessary treatment. biopsies divided into ultrasound-guided, computed tomography (CT)-guided fine-needle aspiration, core (CNB). However, few studies have...
Abstract Rationale: Simple liver cysts are common, and usually benign asymptomatic, requiring little to no treatment. Liver with biliary communication, however, rare require effective treatment avoid recurrence. Patient concerns: A 70-year-old woman breast cancer visited our hospital for Physical examination revealed abdominal distension bilateral lower leg edema. Diagnosis: Abdominal contrast-enhanced computed tomography a giant cyst, inducing inferior vena cava compression that was causing...
An aberrant right posterior hepatic duct is one of the most common risk factors for bile injury during surgical procedures. Complete transection necessitates repair. Recently, endoscopic ultrasound (EUS)-guided hepaticojejunostomy using a forward-viewing echoendoscope to manage complete biliary obstruction in patients with surgically altered anatomy has been reported [1] [2] [3] [4]. Although reports described stenosis anastomoses pancreaticoduodenectomy and modified Child reconstruction,...
An 80-year-old man presented to our hospital with anorexia. esophagogastroduodenoscopy revealed a type 1 tumor occupying the esophagus and diagnosis of esophageal carcinosarcoma was made. A palliative irradiation planned, but as invasion into thoracic aorta suspected on enhanced computed tomography, endovascular aortic repair (TEVAR) performed prevent aorto-esophageal fistula (AEF). AEF has been reported occur in 14.6% patients during after chemoradiotherapy for cancer invading is fatal....
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Appendiceal abscesses sometimes require percutaneous drainage [1]. Recently, endoscopic ultrasound (EUS)-guided through the intestinal tract has become possible, even in cases of pelvic or intra-abdominal resulting from lower gastrointestinal disease. However, this approach is usually performed rectum sigmoid colon [2] [3] [4] [5], and its use challenging for appendiceal because their location. Herein, we report a case abscess successfully treated by EUS-guided transduodenal using...
Abstract Hepatic arteriovenous malformation occurs hyperpulsatile heart failure, hepatic encephalopathy, and ascites as clinical symptoms. Oral medication are effective, but angioembolization or surgery in case of its symptoms worsen.
Most patients with hepatitis E virus (HEV) infection are asymptomatic and improve naturally without any treatment, but even non-immunocompromised individuals may develop persistent HEV infections should be monitored regularly for the onset.