A5021592310- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Pediatric Hepatobiliary Diseases and Treatments
- Pancreatitis Pathology and Treatment
- Esophageal and GI Pathology
- Biliary and Gastrointestinal Fistulas
- Gastrointestinal disorders and treatments
- Gastrointestinal Tumor Research and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Neuroendocrine Tumor Research Advances
- Ultrasound and Hyperthermia Applications
- Gastrointestinal Bleeding Diagnosis and Treatment
- Radio Frequency Integrated Circuit Design
- Gastric Cancer Management and Outcomes
- Advanced Power Amplifier Design
- Polyamine Metabolism and Applications
- Salivary Gland Disorders and Functions
- Foreign Body Medical Cases
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Cells and Metastasis
- Abdominal vascular conditions and treatments
- Advancements in PLL and VCO Technologies
- Neurofibromatosis and Schwannoma Cases
- Thyroid and Parathyroid Surgery
- Dysphagia Assessment and Management
Tokyo Medical University
2016-2025
Weatherford College
2023
RELX Group (Netherlands)
2023
Tokyo Medical University Hospital
2017-2021
Saitama Municipal Hospital
2013-2014
City Hospital
2013-2014
Mitsubishi Electric (United States)
2003
Mitsubishi Electric (Japan)
2003
Mitsubishi Group (Japan)
2003
GlobalFoundries (United States)
2003
Recently, a 22G Franseen needle for EUS-guided fine-needle biopsy (EUS-FNB) with three novel symmetric heels has been developed to adequately obtain core tissue.All 38 consecutive patients pancreatic masses who underwent EUS-FNB using were investigated retrospectively assess the efficacy and safety of needle. Then, outcomes histological assessments tissue obtained by EUS-FNA conventional end-cut type each 30 ductal adenocarcinoma cases compared.An accurate diagnosis was achieved mean 2...
Detection of pancreatic cancer (PC) at a resectable stage is still difficult because the lack accurate detection tests. The development biomarkers in low or non-invasive biofluids essential to enable frequent tests, which would help increase opportunity PC early stages. Polyamines have been reported as possible urine and saliva samples various cancers. Here, we analyzed salivary metabolites, including polyamines, using capillary electrophoresis-mass spectrometry. Salivary were collected from...
Endoscopic ultrasonography-guided pancreatic duct drainage (EUS-PD) has been reported as an alternative for failed conventional endoscopic retrograde cholangiopancreatography (ERCP). However, there are few dedicated devices EUS-PD. Recently, we have developed a new plastic stent to EUS-PD and conducted feasibility study evaluate its efficacy. In the current study, evaluated long-term efficacy of this stent. Thirty patients (61 ± 14.3 years old, 14 men) with acute recurrent pancreatitis...
Endoscopic papillectomy (EP) has been attempted not only for benign lesions but also early ampullary carcinoma (AC). However, there is still no sufficient evidence or consensus regarding the effectiveness of EP AC. Herein, we evaluated expanding indication AC.Between May 1999 and December 2016, 177 patients were diagnosed with tumor before undergoing EP, their clinical histopathological data analyzed retrospectively.There 27 Tis-T1a AC four T1b who underwent EP. Mean size was 14.1 mm 17.0...
ABSTRACT Background and Objectives: EUS-guided tissue acquisition is routinely performed for the diagnosis of gastrointestinal tract adjacent organ lesions. Recently, various types needles have been developed. However, how shape needle tip echoendoscope angle affect puncturability, has not clarified. The aim this experimental study was to compare puncturability several 22-gauge EUS-FNA fine-needle biopsy (EUS-FNB) needles, evaluate effects on puncturability. Materials Methods: following six...
Tract dilation prior to stent placement is an important step in endoscopic ultrasound-guided hepaticogastrostomy. Mukai and colleagues describe their use of a novel catheter with longer balloon, which enables one-step tract the gastric wall, liver parenchyma, bile duct shortening procedure reducing leakage.
Endoscopic intraductal radiofrequency ablation (ID‐RFA) can curatively treat residual lesions after endoscopic papillectomy. This study aimed to verify the tissue invasiveness of ID‐RFA using a novel RF generator and explore its appropriate settings in an animal experiment, followed by small clinical study. Pig liver specimens were ablated dedicated catheter two generators investigate structural differences between them effects produced under various voltage power settings. Appropriate for...
Background: Biliary tract cancers (BTCs), including gallbladder and bile duct cancers, have a poor prognosis. Recent advances in chemotherapy, such as using targeted drugs for specific gene mutations, improved outcomes. Gemcitabine plus cisplatin chemotherapy has been the standard of care primary treatment BTCs, but secondary had not established until recently. In recent years, durvalumab gemcitabine (GCD) is emerging promising regimen, although more evidence needed its effectiveness....
Biloma is a complication of transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) [1]. Despite being the first-line treatment infected bilomas, percutaneous drainage can affect daily life and pose self-extraction risks, particularly in older patients [2]. Endoscopic ultrasound (EUS)-guided offers viable alternative internal biliary drainage; however, it be challenging right liver lobe because its long distance from gastrointestinal (GI) tract [3] [4] [5]. Here,...
An intradiverticular papilla can make biliary cannulation challenging during endoscopic retrograde cholangiopancreatography (ERCP). Some techniques to overcome this issue have been reported, such as the two-devices-in-one-channel method,1 pancreatic guidewire technique,2 precutting technique,3 and rendezvous technique.4 The recently developed traction device5 rotatable sphincterotome might be useful for of an papilla. Here, we report a case successful using device (Figures 1 2). 84-year-old...
Background: Early detection of pancreatic cancer using existing tumor markers is challenging, and novel biomarkers are needed. Apolipoprotein A2 (APOA2), which not directly produced by tumors, may help detect through mechanisms distinct from carbohydrate antigen 19-9 (CA 19-9). This study aimed to evaluate the diagnostic performance APOA2-isoform (APOA2-i) Index in patients with cancer. Methods: Serum levels APOA2-i CA were measured 76 (Stage 0, n = 5; I, 4; II, 15; III, 19; IV, 33) 98...
Abstract Purpose We evaluated the diagnostic and therapeutic capabilities of endoscopic ultrasonography (EUS) in pancreaticobiliary diseases. aimed to validate efficiency detective flow imaging (DFI), shear wave elastography (SWE), other advanced techniques. Methods used new EUS scopes (EG‐740 UT G‐580UR) latest ultrasound equipment (ARIETTA 850) (Fujifilm Healthcare, Kanagawa, Japan). Diagnostic procedures were performed 16 cases, including pancreatic cancer intraductal papillary mucinous...
EUS-guided biliary drainage (EUS-BD) has recently been used for the treatment of not only malignant pancreaticobiliary diseases, but also benign diseases. In most previous studies, EUS-BD was performed using a fully covered self-expandable metallic stent (SEMS), and data focusing on usability plastic stents diseases are limited. We previously developed dedicated to hepaticoenterostomy (EUS-HES), achieved favorable results in feasibility study, although patients had Therefore, aim present...
PuraStat is a novel self-assembling peptide hydrogel developed as hemostatic agent for endoscopic and surgical procedures which can be applied to bleeding from various lesions of the gastrointestinal tract. Yamamoto colleagues present video showing actual hemostasis using sphincterotomy-related bleeding.
Although Spy DS (SpyGlass Direct Visualization System) is considered to be useful for the diagnosis of bile duct strictures and treatment stones, there limited data date validating its efficacy. We hence retrospectively evaluated clinical outcomes use in a large number patients. A total 183 patients who underwent DS-guided procedures indeterminate (n = 93) stones 90) were analyzed retrospectively. All (93/93) with successfully visual observation, 95.7% (89/93) these direct biopsy. The...
Background and study aims Feasibility of EUS-guided choledochoduodenostomy (EUS-CDS) using available lumen-apposing stents (LAMS) is limited by the size common bile duct (CBD) (≤ 12 mm, cut-off for experts; 15 non-experts). We aimed to assess prevalence predictive factors associated with CBD ≥ mm in naïve patients malignant distal biliary obstruction (MDBO). Patients methods This was a prospective cohort involving 22 centers assessment diameter subjective feasibility EUS-CDS performance...
High-intensity focused ultrasound (HIFU) is a novel advanced therapy for unresectable pancreatic cancer (PC). HIFU with chemotherapy being promoted as method to control local advancement by tumor ablation. We evaluated the therapeutic effects of in locally and metastatic PC. PC patients were treated an optional systemic chemotherapy. The FEP-BY02 (Yuande Bio-Medical Engineering) device was used under guidance. Of 176 patients, 89 cases Stage III 87 IV. rate complete ablation 90.3%, while...
AIMTo evaluate the feasibility and reliability of endoscopic transpapillary bile duct biopsy for diagnosis biliary strictures. METHODSA total 360 patients (241 men) who underwent retrograde cholangiopancreatography strictures with from April 2012 to 6429
Objective Endoscopic papillectomy (EP) has been recognized to be a safe and reliable treatment modality for ampullary adenomas. The purpose of this study was determine the safety efficacy endoscopic piecemeal resection laterally spreading adenomas compare these findings with control population smaller conventional tumors treated in same time period. Methods Between May 1999 September 2015, 136 patients underwent EP at Tokyo Medical University hospital. A total 125 en bloc resection, 11...