Nakul Saxena

ORCID: 0000-0002-6717-4975
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About
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Research Areas
  • Breast Cancer Treatment Studies
  • Global Cancer Incidence and Screening
  • Simulation-Based Education in Healthcare
  • Innovations in Medical Education
  • Retinal and Optic Conditions
  • Retinal Diseases and Treatments
  • Colorectal Cancer Screening and Detection
  • Chronic Disease Management Strategies
  • Gastric Cancer Management and Outcomes
  • BRCA gene mutations in cancer
  • Cancer Risks and Factors
  • Healthcare Systems and Reforms
  • Helicobacter pylori-related gastroenterology studies
  • Retinal Imaging and Analysis
  • Multiple Myeloma Research and Treatments
  • Social Media in Health Education
  • Diabetic Foot Ulcer Assessment and Management
  • Esophageal Cancer Research and Treatment
  • Breast Lesions and Carcinomas
  • Online and Blended Learning
  • Surgical Simulation and Training
  • Economic and Financial Impacts of Cancer
  • Dental Research and COVID-19
  • Health Sciences Research and Education
  • Hemophilia Treatment and Research

Takeda (Singapore)
2022-2023

Novartis (Singapore)
2019-2020

SingHealth
2014-2019

Singapore Centre for Environmental Life Sciences Engineering
2018

Nanyang Technological University
2018

Tan Tock Seng Hospital
2015

National University of Singapore
2009-2014

National University Health System
2011-2014

University Medical Center Utrecht
2010-2011

Ministry of Health
2010-2011

Two hospital-based breast cancer databases (University Malaya Medical Center, Malaysia [n = 1513] and National University Hospital, Singapore 2545]) were merged into a regional registry of patients diagnosed between 1990 2007. A review the data found 51% before age 50 years. 72% percent women Chinese followed by Malays (16%), Indians (8%), other races (4%). Median tumor size at presentation was 26 mm about 25% presented with TNM stage III or IV disease. Most tumors ductal histology (87%)....

10.1016/j.breast.2011.01.015 article EN cc-by-nc-nd The Breast 2011-02-13

Background The burden of breast cancer in Asia is escalating. We evaluated the impact ethnicity on survival after multi-ethnic region South East Asia. Methodology/Principal Findings Using Singapore-Malaysia hospital-based registry, we analyzed association between and mortality following 5,264 patients diagnosed 1990 2007 (Chinese: 71.6%, Malay: 18.4%, Indian: 10.0%). compared rates ethnic groups calculated adjusted hazard ratios (HR) to estimate independent effect survival. Malays (n = 968)...

10.1371/journal.pone.0030995 article EN cc-by PLoS ONE 2012-02-21

With population health management being a priority in the Singapore, this paper aims to provide data-driven perspective of initiatives aid program planning and serves as baseline for evaluation future implemented programs.A database with information on patient demographics, services utilization, cost, diagnoses chronic disease from 2008 2013 three regional systems Singapore was used analysis. Patients or more inpatient admissions were considered "Frequent Admitters." Health service...

10.1002/hpm.2300 article EN The International Journal of Health Planning and Management 2015-06-29

Background: Lower extremity amputation (LEA) is defined as the complete loss in transverse anatomical plane of any part lower limb. The objective this study to look at trend and mortality LEA performed diabetes patients from 2008 2013. Methods: All age 15 above with mellitus who had undergone LEAs (both major minor) Tan Tock Seng Hospital, Singapore 1 January 31 December 2013 were included. outcomes interest deaths all causes within 30 days year. Results: Major rate has increased 11.0 per...

10.1177/2010105816663521 article EN cc-by-nc Proceedings of Singapore Healthcare 2016-08-11

Objective: Understanding the health and service utilization of population is critical for Regional Health System’s (RHS) management (PHM) initiatives in Singapore. The RHS database a collaborative effort toward developing national architecture healthcare data across diverse clinical systems with disparate models. This manuscript describes setup an which would facilitate big analytics proactive services research. Materials methods: conglomeration four isolated databases from three RHSs. It...

10.1177/2010105815611440 article EN cc-by-nc Proceedings of Singapore Healthcare 2015-10-16

The prognosis of diabetic kidney disease is poor because epidemiological data have shown that all-cause mortality increases with declining renal function. This study aims to estimate the annual rate stratified by chronic (CKD) stages and identify predictors mortality. Patients Stage 3–5 CKD (estimated glomerular filtration [eGFR] less than 60 mL/min per 1.73 m2) from National Healthcare Group Registry 1 January 2007 31 December were included in this study. patients followed up till 30...

10.1016/j.jcte.2016.01.002 article EN cc-by-nc-nd Journal of Clinical & Translational Endocrinology 2016-01-27

Introduction: The risk of lower extremity amputations (LEAs) in diabetics is 20 times higher than non-diabetics. Clinical practice guidelines recommend that all should receive an annual foot examination to identify high-risk conditions. Despite this recommendation, there little evidence the literature show its effectiveness preventing LEA. This study aims evaluate diabetes screening primary care LEA and factors. Materials Methods: a retrospective cohort diabetic patients who visited National...

10.47102/annals-acadmedsg.v46n11p417 article EN Annals of the Academy of Medicine Singapore 2017-11-15

Introduction Lymph node ratio (LNR, i.e. the of number positive nodes to total excised) is reported be superior absolute involved (pN stage) in classifying patients at high versus low risk death following breast cancer. The added prognostic value LNR over pN addition other factors has never been assessed. Methods All diagnosed with lymph positive, non-metastatic invasive cancer National University Hospital (Singapore) and Malaya Medical Center (Kuala Lumpur) between 1990–2007 were included...

10.1371/journal.pone.0045809 article EN cc-by PLoS ONE 2012-09-24

Aim With an aging Singapore population, there is increasing demand for dementia care. The present study aimed to evaluate the effectiveness and cost‐effectiveness of Primary Care Dementia Clinic (PCDC) in comparison with Memory (MC; hospital‐based) other polyclinics. Methods A quasi‐experimental design was implemented. Effectiveness PCDC assessed through caregiver satisfaction, quality life (caregiver‐rated) adverse events rates. Quality‐of‐Life measures using EuroQol 5 Dimension...

10.1111/ggi.13196 article EN Geriatrics and gerontology international/Geriatrics & gerontology international 2017-11-28

To estimate the prevalence of wet age-related macular degeneration (AMD) in Singapore year 2030. This projection will help planning appropriate care provision and build health services capacity to cater increasing healthcare demand 2030.The number AMD patients aged 40-79 years from all Singaporeans was estimated using rates a local study United Nations population projections for Age-specific mortality accounted for. Additionally, two main scenarios were presented: (1) Projected cases if not...

10.1080/09286586.2016.1193617 article EN Ophthalmic Epidemiology 2016-06-24
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