- Zebrafish Biomedical Research Applications
- Renal and related cancers
- Olfactory and Sensory Function Studies
- Reproductive Biology and Fertility
- Escherichia coli research studies
- Helicobacter pylori-related gastroenterology studies
- Prenatal Screening and Diagnostics
- Viral gastroenteritis research and epidemiology
- Pluripotent Stem Cells Research
- Aquaculture disease management and microbiota
- Regulation of Appetite and Obesity
- Reproductive biology and impacts on aquatic species
- Eosinophilic Esophagitis
- Neurobiology and Insect Physiology Research
- Microbial Applications in Construction Materials
- Receptor Mechanisms and Signaling
- Intestinal and Peritoneal Adhesions
- Chronic Kidney Disease and Diabetes
- Antibiotic Resistance in Bacteria
- Clostridium difficile and Clostridium perfringens research
- Single-cell and spatial transcriptomics
- Fish Ecology and Management Studies
- Phytochemistry and Bioactive Compounds
- Photoreceptor and optogenetics research
- Congenital heart defects research
RIKEN Center for Brain Science
2011-2024
RIKEN BioResource Research Center
2008-2010
RIKEN
2009
Tokyo Medical and Dental University
2007-2008
Tokai University
2008
Saitama International Medical Center
1996-1997
Helicobacter pylori infection is a risk factor for gastric carcinogenesis. High dietary vitamin C intake appears to protect against carcinoma. It has been suggested that exerts the protective effect by scavenging free radicals may be enhanced H. pylori. However, not investigated in relation direct action on In this study, authors attempted clarify possibility both vitro and vivo.Susceptibility testing of (64 strains) was performed agar dilution method. Bactericidal actions were determined...
Because mouse embryonic stem cells (mESCs) do not contribute to the formation of extraembryonic placenta when they are injected into blastocysts, it is believed that mESCs differentiate trophoblast whereas human (hESCs) can express markers exposed bone morphogenetic protein 4 (BMP4) in vitro. To test whether have potential trophoblast, we assessed effect BMP4 on a defined monolayer culture condition. The expression trophoblast-specific transcription factors such as Cdx2, Dlx3, Esx1, Gata3,...
The presence of the enteroaggregative Escherichia coli (EAggEC) heat-stable enterotoxin 1 (EAST1) gene was investigated in 15 strains each EAggEC, enteropathogenic E. (EPEC), EPEC-related non-EPEC serotypes, diffusely adhering (type DAEC) that carries F1845 adhesive pili (or a related adhesin), and enteroinvasive (EIEC) by PCR colony hybridization. EAST1 or its homologue present 53.3% 20% EPEC, 13.3% strains, 6.7% type DAEC. EIEC unrelated with diarrhea had no sequence similarity to gene....
Zebrafish is a useful model organism in neuroscience; however, its gene expression atlas the adult brain not well developed. In present study, we examined of 38 neuropeptides, comparing with GABAergic and glutamatergic neuron marker genes zebrafish by comprehensive situ hybridization. The results are summarized as an 19 coronal planes forebrain. Furthermore, scanned data all sections were made publicly available Adult Brain Gene Expression Database (https://ssbd.riken.jp/azebex/). Based on...
Escherichia coli 73-1 (serotype O73:H33) and 5-2 O89:H-) isolated from patients with diarrhea adhered to tissue culture cells (HeLa HEp-2) as well coverslips (plastic glass) in a diffuse pattern. Adherence of strain was mediated by 110-kbp plasmid designated pEDA1 correlated D-mannose-resistant hemagglutinin (MRHA) detected bovine, sheep, or human erythrocytes. The MRHA region duplicated on the production 57-kDa outer membrane protein whose N-terminal amino acid sequence hydrophobic. In...
Abstract Zebrafish is a useful model organism in neuroscience; however, its gene expression atlas the adult brain not well developed. In present study, we examined of 38 neuropeptides, and glutamatergic neuron marker mix ( slc17a6a, slc17a6b, slc17a7a, slc17a7b ) zebrafish using situ hybridization. The results are summarized as an 19 coronal planes forebrain. Furthermore, scan data all sections were made publicly available database. Based on these data, performed detailed neuroanatomical...
Strain O42 (serotype O44:H18) of enteroaggregative Escherichia coli (EAggEC) has been shown to be pathogenic in volunteer experiments. This strain exhibited plasmid (pO42)-encoded D-mannose-resistant hemagglutinating activity (MRHA) that was detected only at low temperatures (e.g., 0 degrees C) and with human erythrocytes. The production this cryogenic MRHA (cryo-MRHA) observed when the bacteria were grown liquid media strictly regulated by bacterial growth temperatures. Transposon-insertion...
ESCs are most commonly derived from embryos originating oocytes that reached metaphase II. We describe here a novel approach where with all pluripotency parameters were established in which I was converted, the cell cycle perspective, directly into II-like stage without intervening anaphase to telophase transition. The resulting initiate development and reach blastocyst ESC lines then established. Thus, our could represent an ethically acceptable method can exploit typically discarded vitro...
BACKGROUND Helicobacter pylori infection is a risk factor for gastric carcinogenesis. High dietary vitamin C intake appears to protect against carcinoma. It has been suggested that exerts the protective effect by scavenging free radicals may be enhanced H. pylori. However, not investigated in relation direct action on In this study, authors attempted clarify possibility both vitro and vivo. METHODS Susceptibility testing of (64 strains) was performed agar dilution method. Bactericidal...
Helicobacter pylori infection is associated with chronic gastritis and duodenal ulcer disease in both children adults.1, 2 An understanding of H. transmission important for the prevention infection. Although routes not yet clear, previous serologic genetic studies suggest that primarily acquired early life intrafamilial one most common modes transmission.3-5 There is, however, only study used DNA analysis to depict suspected route within home pediatric field.6 Looking direct evidence among a...