A5008726376- Alzheimer's disease research and treatments
- Dementia and Cognitive Impairment Research
- Long-Term Effects of COVID-19
- Neuroinflammation and Neurodegeneration Mechanisms
- Peripheral Neuropathies and Disorders
- COVID-19 Clinical Research Studies
- Epilepsy research and treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- CNS Lymphoma Diagnosis and Treatment
- Restless Legs Syndrome Research
- Neuroscience and Neuropharmacology Research
- Biomedical and Chemical Research
- Parkinson's Disease Mechanisms and Treatments
- Lymphoma Diagnosis and Treatment
- S100 Proteins and Annexins
- Glioma Diagnosis and Treatment
- Autoimmune Neurological Disorders and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Visual perception and processing mechanisms
- Cholinesterase and Neurodegenerative Diseases
- Neurological Complications and Syndromes
- Prion Diseases and Protein Misfolding
- Polyomavirus and related diseases
- Neurological Disease Mechanisms and Treatments
- Neuroscience and Music Perception
University Hospital of Lausanne
2020-2023
University of Lausanne
2018-2023
Czech Academy of Sciences, Institute of Microbiology
2021
Cognitive Neuroimaging Lab
2013
ETH Zurich
2009
Coronavirus disease (COVID-19) has been associated with a large variety of neurologic disorders. However, the mechanisms underlying these complications remain elusive. In this study, we aimed at determining whether symptoms were caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) direct infection or either systemic local proinflammatory mediators.In cross-sectional checked for SARS-CoV-2 RNA quantitative reverse transcription PCR, SARS-CoV-2-specific antibodies, and 49...
Time is embedded in any sensory experience: the movements of a dance, rhythm piece music, words speaker are all examples temporally structured events. In humans, if and how visual cortices perform temporal processing remains unclear. Here we show that both primary cortex (V1) extrastriate area V5/MT causally involved encoding keeping time memory this involvement independent from low-level processing. Most importantly demonstrate V1 come into play simultaneously seem to be functionally linked...
2][3] There is no report of histologic association with vasculitis.We present a case AK5 limbic encephalitis evidence CNS vasculitis. CaseA 58-year-old woman was admitted for investigation headaches, memory impairment, behavioral changes, and sleep disturbances, progressing over approximately 1 month impairing her daily activities.
Central nervous system involvement in Hodgkin lymphoma is extremely rare, especially nodular lymphocyte predominant which usually carries a favorable prognosis, Here we report the case of young patient with lymphoma, who developed progressive and fatal neurological deterioration, requiring very extensive work-up including two biopsies to obtain diagnosis T-cell/histiocyte-rich large B-cell like transformation. This report, includes post-mortem analysis, highlights correlations between...
The year 2022 was marked by the development of numerous new treatments for refractory myasthenia gravis. link between epilepsy and cerebrovascular disorder studied lamotrigine discovered to be optimal treatment choice secondary stroke prevent mortality on patient 45 years older. New randomized study finally demonstrated utility thrombectomy in selected patients with basilar artery occlusion. causal relationship Epstein-Barr infection multiple sclerosis has been proved thanks a large cohort...
Rapidly progressive dementia is distinguished from other neurocognitive disorders by its rapid onset (less than two years first symptoms to diagnosis). It comprises a wide range of etiologies, including Creutzfledt-Jakob disease and Alzheimer's disease. When faced with recent major cognitive impairment, it essential rule out delirium or any cause that may lead decline (such as stroke, encephalitis, epileptic seizure). The work-up based on detailed history (drugs, exposure, medical history),...
ABSTRACT Objective Coronavirus disease (COVID-19) has been associated with a large variety of neurological disorders. However the mechanisms underlying these complications remain elusive. In this study we aimed at determining whether symptoms were caused by SARS-CoV-2 direct infection or either systemic local pro-inflammatory mediators. Methods We checked for RNA RT-qPCR, SARS-CoV-2-specific antibodies and 49 cytokines/chemokines/growth factors (by Luminex) in cerebrospinal fluids (CSF)...
In 2021, we assisted to the publication of new diagnostic criteria, classifications, and guidelines (CIDP, brain tumors, auto-immune encephalitis). Several studies helped define pharmacological management focal generalized epileptic seizures epilepsy in pregnant women. The availability biomarkers approval immunotherapies are modifying landscape dementia management. Endovascular interventions without previous thrombolysis seems be effective anterior circulation acute ischemic stroke (AIS)...
L'année 2020 a vu d'importantes avancées dans le domaine des biomarqueurs sanguins pour diagnostic biologique de la maladie d'Alzheimer.Plusieurs études permettent mieux définir prise en charge l'épilepsie chez femme âge procréer et l'état mal épileptique.Les nouvelles recommandations suisses préhospitalière l'AVC aigu sont cours publication, tout comme cibles leur prévention secondaire.De nombreuses concernant Neuromyelitis Optica Spectrum Disorder ont été publiées.Divers tableaux...