Marleen Margret Mignon Mitschek

ORCID: 0000-0002-6750-8082
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About
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Research Areas
  • Treatment of Major Depression
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Tryptophan and brain disorders
  • Neurotransmitter Receptor Influence on Behavior
  • Mental Health Treatment and Access
  • Epilepsy research and treatment
  • Bipolar Disorder and Treatment
  • Digital Mental Health Interventions
  • Migraine and Headache Studies
  • Stress Responses and Cortisol
  • Attachment and Relationship Dynamics
  • Metabolism and Genetic Disorders
  • Prenatal Substance Exposure Effects
  • Pharmacological Effects and Toxicity Studies
  • Neuroendocrine regulation and behavior
  • Maternal Mental Health During Pregnancy and Postpartum
  • Adolescent and Pediatric Healthcare
  • Mental Health Research Topics
  • Neuroscience of respiration and sleep

Medical University of Vienna
2019-2022

Sex-related effects on the evolution and phenotype of major depressive disorder (MDD) were reported previously.This European multicenter cross-sectional study compared sociodemographic, clinical, treatment patterns between males females in a real-world sample 1410 in- outpatients with current MDD.Male MDD patients (33.1%) rather inpatients, suffered from moderate to high suicidality levels, received noradrenergic specific serotonergic antidepressants (ADs) as first-line AD treatment,...

10.1002/da.23165 article EN Depression and Anxiety 2021-06-10

The present multicenter study aimed at defining the clinical profile of patients with major depressive disorder (MDD) and comorbid migraine.Demographic information for 1410 MDD vs without concurrent migraine were compared by descriptive statistics, analyses covariance, binary logistic regression analyses.The point prevalence rate was 13.5% female 6.2% male patients. + significantly younger, heavier, more likely female, non-Caucasian origin, outpatient, suffering from asthma. presence...

10.1093/ijnp/pyaa035 article EN cc-by-nc The International Journal of Neuropsychopharmacology 2020-05-15

Valproic acid (VPA) has been increasingly shown to trigger hyperammonemic encephalopathies in patients suffering from urea cycle defects and those receiving polypharmacy. We report on two cases of psychiatric inpatients with regular VPA intake who showed severe cognitive impairment due non-cirrhotic hyperammonaemia without overdosing. In the first case, OTC deficiency appeared be underlying cause a comatose state middle-aged bipolar female patient. Besides hyperammonemia, we identified...

10.1016/j.jadr.2021.100186 article EN cc-by-nc-nd Journal of Affective Disorders Reports 2021-06-16

Background: When investigating the neurobiology of suicidal behavior, Monoamino Oxidase A ( MAOA ) is one prime suspects to consider. Interestingly, dysregulation has also been associated with violent behavior in previous publications. In present study, we aimed establish an association between polymorphisms gene and methylation status Exon I, suicide attempts methods a sample affective disorder patients. Methods: Eight hundred fourteen Caucasian patients were assessed at Department...

10.3389/fpsyt.2021.667191 article EN cc-by Frontiers in Psychiatry 2021-08-02

Introduction Although numerous effective antidepressant (AD) strategies are available for the treatment of major depressive disorder (MDD), many patients do not achieve satisfactory response. Objectives The aims present European, cross-sectional, multicenter, naturalistic study were (1) to determine proportion suffering from primary MDD who received additional psychotherapy their ongoing psychopharmacotherapy and (2) identify associated socio-demographic clinical patterns. Methods Patients...

10.1192/j.eurpsy.2022.229 article EN cc-by-nc-nd European Psychiatry 2022-06-01
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