A5036233736- Action Observation and Synchronization
- Motor Control and Adaptation
- Neurobiology of Language and Bilingualism
- Transcranial Magnetic Stimulation Studies
- Neurological disorders and treatments
- Neural and Behavioral Psychology Studies
- EEG and Brain-Computer Interfaces
- Parkinson's Disease Mechanisms and Treatments
- Functional Brain Connectivity Studies
- Visual perception and processing mechanisms
- Vestibular and auditory disorders
- Stroke Rehabilitation and Recovery
- Language, Metaphor, and Cognition
- Genetic Neurodegenerative Diseases
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Spatial Neglect and Hemispheric Dysfunction
- Psychosomatic Disorders and Their Treatments
- Neural dynamics and brain function
- Hemispheric Asymmetry in Neuroscience
- Child and Animal Learning Development
- Tactile and Sensory Interactions
- Ophthalmology and Eye Disorders
- Botulinum Toxin and Related Neurological Disorders
- Nuclear Receptors and Signaling
RWTH Aachen University
2016-2025
Forschungszentrum Jülich
2016-2025
Jülich Aachen Research Alliance
2012-2025
Universitätsklinikum Aachen
2013-2024
Brain (Germany)
2004-2022
University of Lübeck
2003-2012
Goethe University Frankfurt
1999-2010
Hvidovre Hospital
2008-2010
University of Cologne
2007-2010
University Hospital Schleswig-Holstein
2003-2010
Functional magnetic resonance imaging (fMRI) was used to localize brain areas that were active during the observation of actions made by another individual. Object- and non-object-related with different effectors (mouth, hand foot) presented. Observation both object- determined a somatotopically organized activation premotor cortex. The somatotopic pattern similar classical motor cortex homunculus. During object-related actions, an activation, also organized, additionally found in posterior...
Abstract Functional magnetic resonance imaging (fMRI) was used to localize brain areas that were active during the observation of actions made by another individual. Object‐ and non‐object‐related with different effectors (mouth, hand foot) presented. Observation both object‐ determined a somatotopically organized activation premotor cortex. The somatotopic pattern similar classical motor cortex homunculus. During object‐related actions, an activation, also organized, additionally found in...
Abstract Functional magnetic resonance imaging (fMRI) was used to localize brain areas active during manipulation of complex objects. In one experiment subjects were required manipulate objects for exploring their macrogeometric features as compared a simple smooth object (a sphere). second asked and silently name them upon recognition not recognizable without covert naming. Manipulation resulted in an activation ventral premotor cortex [Brodmann's area (BA) 44], region the intraparietal...
It has been shown in nonhuman primates that the posterior parietal cortex is involved coordination of arm and eye movements space, whereas anterior intraparietal area lateral bank sulcus plays a crucial role fine finger movements, such as grasping. In this study we show by optoelectronic movement recordings patients with cortical lesions involving have selective deficits required for object grasping, reaching much less disturbed. Patients sparing lining showed intact grasping behavior....
When our PC goes on strike again we tend to curse it as if were a human being. Why and under which circumstances do attribute human-like properties machines? Although humans increasingly interact directly with machines remains unclear whether implicitly intentions them and, so, such interactions resemble human-human neural level. In social cognitive neuroscience the ability desires others is being referred having Theory of Mind (ToM). With present study investigated an increase...
We aimed to objectify and compare persisting self-reported symptoms in initially hospitalized non-hospitalized patients after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by applying clinical standardized measures.We conducted a cross-sectional study of adult confirmed SARS-CoV-2 including medical history, neurological examination, blood markers, neuropsychological testing, patient-reported outcome measures (PROMs), brain magnetic resonance imaging (MRI).Fifty...
The inverse effects of creatine supplementation and sleep deprivation on high energy phosphates, neural creatine, cognitive performances suggest that is a suitable candidate for reducing the negative deprivation. With this, main obstacle limited exogenous uptake by central nervous system (CNS), making only effective over long-term diet weeks. Thus far, repeated dosing weeks has been studied, yielding detectable changes in CNS levels. Based hypothesis extracellular availability increased...
Broca's region in the dominant cerebral hemisphere is known to mediate production of language but also contributes comprehension.Here, we report differential participation imagery motion humans.Healthy volunteers were studied with functional magnetic resonance imaging (fMRI) while they imagined movement trajectories following different instructions.Imagery right-hand finger movements induced a cortical activation pattern including dorsal and ventral portions premotor cortex, frontal medial...
Objective : To study the mechanisms underlying recovery from middle cerebral artery infarction in 7 patients with an average age of 53 years who showed marked hand function after acute severe hemiparesis caused by their first-ever stroke.Interventions: Assessment motor functions, transcranial magnetic stimulation, somatosensory evoked potentials, resonance imaging, and positron emission tomographic measurements regional blood flow during finger movement activity. Results:The infarctions...
We studied the role of remote metabolic depressions and pyramidal tract involvement regarding motor recovery following a first hemiparetic ischemic stroke. In 23 patients regional cerebral glucose metabolism (rCMRGlu) was measured with positron emission tomography location spatial extent stroke lesions were assessed by magnetic resonance imaging. Motor impairment during acute chronic stages (4 weeks after stroke) determined score recordings evoked potentials. Twelve recovered significantly,...
Recovery from hemiparesis after stroke has been shown to involve reorganization in motor and premotor cortical areas. However, whether poststroke recovery also depends on changes remote brain structures, ie, diaschisis, is as yet unresolved. To address this question, we studied regional cerebral blood flow 7 patients (mean+/-SD age, 54+/-8 years) their first hemiparetic stroke.We analyzed imaging data voxel by using a principal component analysis which coherent functional networks could be...
Somatosensory and motor disturbances of hand function were examined in 9 patients with parietal lobe lesions. A quantitative score was used for the elaboration sensorimotor profiles displaying relative degree functional impairment. In anterior lesions somaesthesis clearly more disturbed than function. Simple aspects (surface sensibility, two-point discrimination, position sense) to about same as complex somatosensory (tactile recognition) tasks. On other hand, posterior showed preferential...
The cognitive and neural representation of abstract words is still an open question for theories embodied cognition. Generally, it proposed that are grounded in the activation sensorimotor or at least experiential properties, exactly as concrete words. Further behavioral propose multiple representations evoked by We conducted a functional magnetic resonance imaging (fMRI) study to investigate correlates multi-word expressions action context. Participants were required read simple sentences...