A5075538338- Medical Imaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Radiation Detection and Scintillator Technologies
- Radiomics and Machine Learning in Medical Imaging
- Functional Brain Connectivity Studies
- Glioma Diagnosis and Treatment
- Atomic and Subatomic Physics Research
- Advanced X-ray and CT Imaging
- Neural and Behavioral Psychology Studies
- Radiopharmaceutical Chemistry and Applications
- Motor Control and Adaptation
- Visual perception and processing mechanisms
- Advanced Neuroimaging Techniques and Applications
- Advanced Radiotherapy Techniques
- Spatial Neglect and Hemispheric Dysfunction
- Action Observation and Synchronization
- Transcranial Magnetic Stimulation Studies
- Neuroscience and Neuropharmacology Research
- Lanthanide and Transition Metal Complexes
- Memory and Neural Mechanisms
- Memory Processes and Influences
- Neural dynamics and brain function
- Hemispheric Asymmetry in Neuroscience
- EEG and Brain-Computer Interfaces
- MRI in cancer diagnosis
Forschungszentrum Jülich
2015-2025
Life & Brain (Germany)
2021-2024
Institute of Neurobiology and Molecular Medicine
2013
Brain (Germany)
2006
Stadtwerke Jülich (Germany)
2004-2006
Imaging Center
2006
Heinrich Heine University Düsseldorf
1995-1999
Ernst Ruska Centre
1997
Objective : To study the mechanisms underlying recovery from middle cerebral artery infarction in 7 patients with an average age of 53 years who showed marked hand function after acute severe hemiparesis caused by their first-ever stroke.Interventions: Assessment motor functions, transcranial magnetic stimulation, somatosensory evoked potentials, resonance imaging, and positron emission tomographic measurements regional blood flow during finger movement activity. Results:The infarctions...
We used PET to determine which brain regions are implicated when normal volunteers bisect horizontal lines and point dots in near (peripersonal) or far (extrapersonal) space. Studies of line bisection patients with right hemisphere lesions have shown that performance can be severely impaired either space while remaining within limits the other spatial domain. Likewise, clinical dissociations between pointing objects been reported. The functional anatomy these has not demonstrated...
Abstract The commonsense view of religious experience is that it a preconceptual, immediate affective event. Work in philosophy and psychology, however, suggest an attributional cognitive phenomenon. Here the neural correlates are investigated using functional neuroimaging. During recitation, self‐identified subjects activated frontal–parietal circuit, composed dorsolateral prefrontal, dorsomedial frontal medial parietal cortex. Prior studies indicate these areas play profound role...
The adult primate brain is capable of modifying rapidly the size cortical receptive fields or motor output modules in response to altered synaptic input. We used positron emission tomography (PET) map regional cerebral blood flow changes related voluntary finger movements patients with tumours occupying hand area cortex. All showed activations solely outside tumour. Compared unaffected side, were shifted by 9-43 mm either along mediolateral body representation cortex into premotor parietal...
Summary After the successful clinical introduction of PET/CT, a novel hybrid imaging technology combining PET with versatile attributes MRI is emerging. At Forschungszentrum Jülich, one four prototypes available worldwide commercial 3T newly developed BrainPET insert has been installed, allowing simultaneous data acquisition and MRI. The equipped LSO crystals 2.5 mm width Avalanche photodiodes (APD) as readout electronics. Here we report on some performance characteristics obtained by...
Until recently, no direct comparison between [ 15 O]water positron emission tomography (PET) and arterial spin labeling (ASL) for measuring cerebral blood flow (CBF) was possible. With the introduction of integrated, hybrid magnetic resonance (MR)-PET scanners, such a becomes feasible. This study presents results CBF measurements recorded simultaneously with ASL. A 3T MR-BrainPET scanner used simultaneous acquisition pseudo-continuous ASL (pCASL) imaging (MRI) PET. Quantitative values were...
The aim of this study was to evaluate further the role precuneus in episodic memory retrieval. specific hypothesis addressed that is involved retrieval irrespective imagery content. Two groups six right-handed normal male volunteers took part study. Each subject underwent [15O]butanol-PET scans. In each trials, task began with injection a bolus 1500 MBq [15O]butanol. For Group 1, 12 word pair associates were presented visually, for 2 auditorily. subjects group had learn and retrieve two sets...
Purpose: The use of magnetic resonance (MR) radiofrequency (RF) surface coils is a prerequisite for high-quality positron emission tomography (PET)/MR imaging. In lack in-gantry transmission (TX) sources, the exact position RF unknown in PET/MR, and may, therefore, lead to false attenuation correction (AC) (EM) data. authors assess lesion background quantification AC-PET by mimicking different PET/MR imaging situations using whole-body (WB) PET-only tomograph. Methods: Phantom experiments...
Abstract The aim of this study was to identify the cerebral areas activated during kinematic processing movement trajectories. We measured regional blood flow (rCBF) learning, performance and imagery right‐hand writing in eight right‐handed volunteers. Compared with viewing space, increases rCBF were observed left motor, premotor frontomesial cortex, right anterior cerebellum all conditions, related mean tangential velocity. No occurred these imagery. Early learning new ideomotor...
In positron emission tomography/computed tomography (PET/CT) hybrid imaging attenuation correction (AC) of the patient tissue and table is performed by converting CT-based Hounsfield units (HU) to linear coefficients (LAC) PET. When applied new field hardware component AC in PET/magnetic resonance (MR) imaging, this conversion method may result local overcorrection PET activity values. The aim study thus was optimize parameters for components PET/MR. Systematic evaluation optimization HU LAC...
The spatial extent of amyloid, tau, and neurodegeneration, derived from PET imaging, has higher diagnostic performance for cognitive impairment severity compared with standardized uptake value ratios.
Positron Emission Tomography (PET) images are prone to motion artefacts due the long acquisition time of PET measurements. Recently, simultaneous magnetic resonance imaging (MRI) and have become available in first generation Hybrid MR-PET scanners. In this work, elimination head neuroimages is achieved by a new approach utilising MR-based tracking combination with list mode data correction for acquisitions. The method comprises accurate measurements, an intra-frame minimising reconstruction...