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Merle C. Hoenig

ORCID: 0000-0002-0831-750X
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About
Contact & Profiles
A5038004617
Research Areas
  • Dementia and Cognitive Impairment Research
  • Cancer-related cognitive impairment studies
  • Alzheimer's disease research and treatments

University Hospital Cologne
 2024-2025

University of Cologne
 2024-2025

Forschungszentrum Jülich
 2024-2025

University of Brescia
 2024

 Association Between Years of Education and Amyloid Burden in Patients With Subjective Cognitive Decline, MCI, and Alzheimer Disease
OPENALEX - Publications 
Merle C. Hoenig Daniele Altomare Camilla Caprioglio Lyduine E. Collij Frederik Barkhof and 24 more Bart Van Berckel Philip Scheltens Gill Farrar Mark Battle Hendrik Theis Kathrin Giehl Gérard N. Bischof Valentina Garibotto José Luís Molinuevo Oriol Grau‐Rivera Julien Delrieu Pierre Payoux Jean‐François Démonet Agneta Nordberg Irina Savitcheva Zuzana Walker Paul Edison Andrew Stephens Rossella Gismondi Frank Jessen C. J. Buckley Juan Domingo Gispert Giovanni B. Frisoni Alexander Drzezga

ObjectivesHigher-educated patients with Alzheimer disease (AD) can harbor greater neuropathologic burden than those less education despite similar symptom severity.In this study, we assessed whether observation is also present in potential preclinical AD stages, namely individuals subjective cognitive decline and clinical features increasing likelihood (SCD+). MethodsAmyloid-PET information ([ 18 F]Flutemetamol or [ F]Florbetaben) of SCD+, mild impairment (MCI), were retrieved from the...

10.1212/wnl.0000000000208053 article EN cc-by Neurology 2024-02-20
 “Fill States”: PET-derived Markers of the Spatial Extent of Alzheimer Disease Pathology
OPENALEX - Publications 
Elena Doering Merle C. Hoenig Kathrin Giehl Verena Dzialas Grégory Andrassy and 23 more Anna S. Bader Andreas Bauer David Elmenhorst Johannes Ermert Silke Frensch Elena Jaeger Frank Jessen Philipp Krapf Tina Kroll Christoph Lerche Julia Lothmann Andreas Matusch Bernd Neumaier Oezguer A. Onur Alfredo Ramı́rez Nils Richter Frederik Sand Lutz Tellmann Hendrik Theis Philip Zeyen Thilo van Eimeren Alexander Drzezga Gérard N. Bischof

The spatial extent of amyloid, tau, and neurodegeneration, derived from PET imaging, has higher diagnostic performance for cognitive impairment severity compared with standardized uptake value ratios.

10.1148/radiol.241482 article EN Radiology 2025-03-01
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