A5100317880- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Global Cancer Incidence and Screening
- Esophageal Cancer Research and Treatment
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Hepatitis C virus research
- Cancer Risks and Factors
- Liver physiology and pathology
- Cancer-related molecular mechanisms research
- Global Public Health Policies and Epidemiology
- Epigenetics and DNA Methylation
- Multiple and Secondary Primary Cancers
- Anesthesia and Pain Management
- Global Health Care Issues
- Helicobacter pylori-related gastroenterology studies
- Neurological Disease Mechanisms and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Sports Performance and Training
- Smoking Behavior and Cessation
- Anesthesia and Sedative Agents
- Medical Research and Treatments
- Sports Dynamics and Biomechanics
- Cholesterol and Lipid Metabolism
Ningxia Medical University
2024
Third Xiangya Hospital
2023-2024
Central South University
2023-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2023
Ministry of Industry and Information Technology
2023
Beijing Institute of Technology
2023
Second Hospital of Anhui Medical University
2022
Anhui Medical University
2022
Bohai University
2021
Xinjiang Medical University
2018
Abstract Objective: Liver cancer is one of the most common cancers and major cause deaths in China, which accounts for over 50% new cases worldwide. The systematic liver statistics including projection through 2030 could provide valuable information prevention control strategies experience other countries. Methods: burden China 2014 was estimated using 339 registries' data selected from Chinese National Cancer Center (NCC). Incident 22 registries were applied temporal trends 2000 to 2014....
Abstract Untethered mobile micro‐/nanomotors (MNMs), as newly‐emerging attractive and versatile nanotechnologies, are expected to be the next‐generation disease treatment tools, for breaking through limitations of conventional passive drug delivery manner. However, advances in these fascinating platforms have been hampered by complexity biological environment particularity microenvironment. Consequently, specific design strategies clinical imaging techniques essential ensure high‐efficiency...
In 2020, stomach cancer was the fifth most commonly diagnosed and fourth leading cause of cancer-related death worldwide. Due to relatively huge population base poor survival rate, is still a threat in China, accounts for nearly half cases Fortunately, incidence mortality rates presented declining trend owing change individual life styles persistent efforts prevent from governments at all levels. <i>Helicobacter pylori</i> (<i>H. pylori</i>) infection, eating habits, smoking, history...
Background: Transdermal drug delivery system (TDDS) curing rheumatoid arthritis (RA) for long-term treatment can improve patients' compliance and reduce the accumulation of side effects. However, TDDS is constrained by tight junction stratum corneum low permeation efficiency. It necessary to adopt proper methods ensure therapeutic effect. The transethosome (TE), which derived from transfersome ethosome (E), containing a high content ethanol along with an edge activator or enhancer, has...
Hepatic fibrosis is a chronic liver disease that lacks effective pharmacotherapeutic treatments. As part of the disease's mechanism, hepatic stellate cells (HSCs) are activated by damage-related stimuli to secrete excessive extracellular matrix, leading collagen deposition. Currently, drug delivery system targets HSCs in treatment remains an urgent challenge due poor controllability release. Since level reactive oxygen species (ROS) increases sharply (aHSCs), we designed ROS-responsive...
Background Fear of cancer recurrence is a major source stress and unmet need for colorectal patients. Objective This review aimed to identify factors influencing fear in Methods Multiple electronic databases were systematically searched studies from inception January 2024 using concepts “colorectal neoplasm,” “fear,” “recurrence.” Two authors independently screened, assessed the quality eligible studies, extracted relevant data. The synthesis effect sizes was conducted R software version...
Background Understanding disparities in the burden of cancer attributable to smoking is crucial inform and improve tobacco control measures. In this report, we estimate population fraction (PAF) cancers deaths at national provincial levels China. Methods Using mortality data from 978 counties, a nationwide survey relative risks prospective study 0.5 million adults China, calculated absolute (non-standardised) standardised numbers proportions among 30 years older active second-hand 2014...
China is faced with heavy burdens caused by lung cancer, which has climbed to the top of both cancer incidence and mortality spectrums. The age-standardized rates have shown a trend gradual up-trends in last decades, while crude rise much quickly due aging population. Although improvement health care contributed better survival its prognosis still challenging. Apart from common risk factors such as tobacco use, air pollution, occupational hazards, some specific like Chinese-style cooking...
Gastric carcinogenesis is a multistep process initiating with chronic gastritis and progressing through atrophy, intestinal metaplasia, dysplasia to carcinoma. This study aims comprehensively investigate sociodemographic disparities in each stage of gastric estimate what extent the inequalities could be ascribed risk factors cancer (GC).We used baseline data from community-based China's high-risk areas, totalling 27094 participants. mucosa status was ascertained by endoscopy biopsies. An...
China have implemented population-based esophageal cancer (EC) screening programs, however, the participant rates were relatively low. This study was conducted to examine association between prevention knowledge and EC participation (PRs).Data in analyses obtained from a program four provinces since 2007. In course of 2007-2016, participants who evaluated as high risk for subsequently recommended endoscopy examination included final analysis. One-way analysis variance test, Chi-square test...
A population-based cancer screening program in rural China, targeting three types of that are most prevalent these areas, including esophageal, stomach, and liver was awarded by the government China since 2007. two-step design with risk assessment based on questionnaire interview HBsAg test strip subsequent clinical intervention for high-risk populations adopted free charge at local hospitals designated program. The participate rate rates important to find appropriate strategies improve...
Benchmark data on the population-level economic burden are critical to inform policymakers about liver cancer control. However, comprehensive in China currently limited.A prevalence-based approach from a societal perspective was used quantify annual of 2019 2030. Detailed per-case medical/non-medical expenditure and work-loss days were extracted multicenter survey. The numbers/rates new/prevalent cases deaths, survival, population-related parameters Global Burden Disease literature. All...
Importance Surveillance endoscopy is recommended for patients with low-grade intraepithelial neoplasia (LGIN); high-quality evidence about the use of surveillance and esophageal squamous cell carcinoma (ESCC) incidence in LGIN important but limited. Objective To estimate long-term ESCC rates association between incidence. Design, Setting, Participants This community-based, multicenter, prospective cohort study 9 regions rural China included diagnosed by endoscopic screening July 1, 2007,...
There is little information about contributions of the well-known risk factors to liver cancer burden. We conducted a comparative study estimate burden attributable major factors.Liver deaths for adults were estimated from 978 county-level surveillance points in China 2014. Risk identified International Agency Research on Cancer and World Fund International. Population fraction (PAF) by age, sex, province was calculated using multiple formulas.In total, 72.4% could be studied factors....
Abstract Background Risk‐stratified endoscopic screening (RSES), which offers endoscopy to those with a high risk of esophageal cancer, has the potential increase effectiveness and reduce demands compared universal strategy (i.e., for all targets without prediction). Evidence RSES in high‐risk areas China is limited. This study aimed estimate whether based on 22‐score squamous cell carcinoma (ESCC) prediction model could optimize ESCC China. Methods Eight epidemiological variables were...
Abstract Background: Large disparities exist in liver cancer burden trends across countries but are poorly understood. We aimed to investigate the global trajectories of burden, explore driving forces, and predict future trends. Methods: Data on 204 territories from 1990 2019 were extracted Global Burden Disease Study. The age-standardized incidence rate (ASIR) mortality (ASMR) defined using growth mixture models. Five major risk factors contributing changes ASIR or ASMR socioeconomic...