A5115603194- Venous Thromboembolism Diagnosis and Management
- Acute Myocardial Infarction Research
- Atrial Fibrillation Management and Outcomes
- Bone Tissue Engineering Materials
- Congenital Heart Disease Studies
- Cardiovascular Function and Risk Factors
- Pulmonary Hypertension Research and Treatments
- Parasite Biology and Host Interactions
- Parasites and Host Interactions
- Heart Failure Treatment and Management
- Cancer-related molecular mechanisms research
- Colorectal Cancer Screening and Detection
- Pregnancy and preeclampsia studies
- Advanced biosensing and bioanalysis techniques
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Cardiac electrophysiology and arrhythmias
- Multiple and Secondary Primary Cancers
- Blood Coagulation and Thrombosis Mechanisms
- Global Cancer Incidence and Screening
- Parasitic Infections and Diagnostics
- Metal Extraction and Bioleaching
- Gestational Diabetes Research and Management
- Advanced Thermoelectric Materials and Devices
- Orthopaedic implants and arthroplasty
Guangxi University
2022-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2025
Zhejiang Pharmaceutical College
2025
Zhejiang University
2007-2025
Institute of Geochemistry
2025
Guangzhou University
2022-2024
Wuhan University
2020-2024
Renmin Hospital of Wuhan University
2020-2024
Ningbo University
2024
Suzhou Municipal Hospital
2018-2023
Fibroblast growth factor 21 (FGF-21) is a metabolic regulator with multiple beneficial effects on glucose homeostasis and lipid metabolism in animal models. The relationship between plasma levels of FGF-21 coronary heart disease (CHD) unknown.This study aimed to investigate the correlation serum patients disease. We performed logistic regression analysis relation CHD without diabetes hypertension. This was conducted Departments Endocrinology Cardiovascular Diseases at two University...
Background Fibroblast growth factor 21 (FGF21) is a hepatic hormone involved in the regulation of lipid and carbohydrate metabolism. This study aims to test hypothesis that elevated FGF21 concentrations are associated with change renal function presence left ventricular hypertrophy (LVH) different stages chronic kidney disease (CKD) progression. Methodology/Principal Findings 240 subjects including 200 CKD patients (146 outpatients 54 long-term hemodialytic patients) 40 healthy control were...
In 2020, stomach cancer was the fifth most commonly diagnosed and fourth leading cause of cancer-related death worldwide. Due to relatively huge population base poor survival rate, is still a threat in China, accounts for nearly half cases Fortunately, incidence mortality rates presented declining trend owing change individual life styles persistent efforts prevent from governments at all levels. <i>Helicobacter pylori</i> (<i>H. pylori</i>) infection, eating habits, smoking, history...
Abstract Unlocking the full potential of mRNA immunotherapy necessitates targeted delivery to specific cell subsets in spleen. Four‐component lipid nanoparticles (LNPs) utilized numerous clinical trials are primarily limited hepatocyte and muscular targeting, highlighting imperative demand for simplified non‐liver systems. Herein, we report rational design one‐component ionizable cationic lipids selectively deliver spleen T cells with high efficacy. Unlike tertiary amine‐based involved LNPs,...
<h3>Importance</h3> The incidence of acute myocardial infarction has increased over the past decades in China, and management challenges include an unbalanced economy, disparate resources, variable access to medical care across nation. <h3>Objective</h3> To examine variations outcomes patients with ST-segment elevation among 3 levels hospitals typical Chinese public hospital model. <h3>Design, Setting, Participants</h3> This cross-sectional study used data from China Acute Myocardial...
Population-level economic burden is essential for prioritizing healthcare resources and budget making in the future. However, little known about of lung cancer China.A prevalence-based approach was adopted to estimate cancer, including direct expenditure (medical non-medical) indirect cost (disability premature death). Data on work-loss days per patient each year post-diagnosis were obtained from two primary surveys. Other parameters literatures official reports. Projections conducted based...
Repairing articular cartilage defects is a great challenge due to the poor self-regenerative capability of cartilage. Hydrogel-based tissue engineering has been considered an effective strategy. In this study, inspired by mussel chemistry, catechol-modified chitosan (CS-C) hydrogel was prepared under catalysis horseradish peroxidase/hydrogen peroxide (HRP/H2O2) for defect repair in rat model. The rheological and swelling properties biodegradation behavior CS-C were investigated. Besides,...
Nature has developed a wide range of functional microstructures with optimized mechanical properties over millions years evolution. By learning from nature’s excellent models and principles, biomimicry provides practicable strategy for designing fabricating the next smart materials enhanced properties. Nevertheless, complicated micro-structural constructions in nature are beyond ability conventional processes, hindering developments biomimetic research its forthputting engineering systems....
Abstract Background Recent publications reported a paradoxical finding that there was an inverse association between the number of standard modifiable risk factors (SMuRFs; smoking, hypertension, diabetes, and hyperlipidemia) mortality in patients with myocardial infarction. However, current evidence is only limited to those highly developed countries advanced medical management systems. Methods The China Acute Myocardial Infarction registry prospective observational study including acute...
BackgroundTherapies are urgently required to ameliorate pathological cardiac hypertrophy and enhance function in heart failure. Our preliminary experiments have demonstrated that exogenous NADPH exhibits a positive inotropic effect on isolated heart. This study aims investigate the effects of failure, as well underlying mechanisms involved.MethodsEndogenous plasma contents were determined patients with chronic failure control adults. The investigated toad or rat isoproterenol (ISO)–induced...
Abstract Doping Mn 2+ in newly emerged lead‐free metal halides to access versatile optoelectronic applications is highly desired. However, understanding the chemical pathway of doping and precisely controlling it remains challenging. Here, crucial role initial surface adsorption kinetics demonstrated, step effectively optimized by a moderate Lewis base ligand. The results show that not only concentration Cs 3 Cu 2 I 5 modulated flexibly but also produced :Mn microcrystals exhibit tuned...
This study examined whether folate and vitamin B12 imbalance is associated with gestational diabetes mellitus (GDM) explored interactions between B maternal risk factors for GDM.A cross-sectional was performed in 406 Chinese pregnant women. Serum folate, , blood glucose concentrations were measured at 24 to 28 weeks gestation during GDM screening. A diagnosis of made based on International Association Diabetes Pregnancy Study Groups criteria (fasting plasma [FPG] ≥5.1 mM, 1-hour ≥10.0 or...
Intentional doping plays a pivotal role in customizing metal halides' electronic and optical features. This work manipulates the incorporation distribution of Mn2+ Cu(I) halide by controlling elemental steps involved growth-doping kinetics as well investigates localized lattice structures different configurations. Complementary experimental theoretical results demonstrate that uniform relatively high level can be achieved step-tailored strategy encompasses reducing growth rate matrix,...
The progress of mRNA therapeutics underscores the imperative demand for development targeted delivery systems. While cationic polymers hold promise as genetic vectors, their poor in vivo efficacy and numerous variants highlight urgent need a universal functionalization strategy to bolster capabilities. Here, we present versatile transform low‐cost commercial into phospholipidated alkylated (PAPs), enabling efficient organ‐selective vivo. This straightforward post‐functionalization method can...
The progress of mRNA therapeutics underscores the imperative demand for development targeted delivery systems. While cationic polymers hold promise as genetic vectors, their poor in vivo efficacy and numerous variants highlight urgent need a universal functionalization strategy to bolster capabilities. Here, we present versatile transform low‐cost commercial into phospholipidated alkylated (PAPs), enabling efficient organ‐selective vivo. This straightforward post‐functionalization method can...