A5088146721- Colorectal Cancer Screening and Detection
- Global Cancer Incidence and Screening
- Lung Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Pleural and Pulmonary Diseases
- Cancer-related molecular mechanisms research
- Tracheal and airway disorders
- Liquid Crystal Research Advancements
- Cancer Risks and Factors
- Intraocular Surgery and Lenses
- Air Quality and Health Impacts
- Climate Change and Health Impacts
- MicroRNA in disease regulation
- Nonlinear Dynamics and Pattern Formation
- Multiple and Secondary Primary Cancers
- Liver Disease Diagnosis and Treatment
- Thermoregulation and physiological responses
- Glaucoma and retinal disorders
- Helicobacter pylori-related gastroenterology studies
- Cancer, Lipids, and Metabolism
- Esophageal and GI Pathology
- Advanced Topics in Algebra
- Injury Epidemiology and Prevention
- Nutritional Studies and Diet
- Hepatitis B Virus Studies
Tianjin Medical University General Hospital
2025
Daping Hospital
2017-2025
Army Medical University
2013-2025
Shenzhen Nanshan Center for Chronic Disease Control
2015-2025
Prince Charles Hospital
2020-2024
Shanghai Pulmonary Hospital
2014-2024
Tongji University
2014-2024
The University of Queensland
2024
Fujian Medical University
2010-2024
Affiliated Eye Hospital of Wenzhou Medical College
2015-2024
Abstract STAT3 has been strongly implicated in human malignancies, and constitutive activation of serves a crucial role cell survival, angiogenesis, immune evasion, inflammation. In this study, we showed that nitidine chloride, natural phytochemical alkaloid derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through signaling cascade. Nitidine chloride dose dependently suppressed VEGF-induced endothelial proliferation, migration, tubular structure formation vitro...
In this review, we offer a concise overview of liver cancer epidemiology in China and worldwide from the official databases GLOBOCAN 2020 National Cancer Registry China. We also summarized evidence for main risk factors associated with discuss strategies implemented to control burden. Overall, was sixth most commonly diagnosed third leading cause cancer-related death 2020. Although contributed nearly half cases across world alone, incidence mortality rates presented declining trend owing...
In 2020, stomach cancer was the fifth most commonly diagnosed and fourth leading cause of cancer-related death worldwide. Due to relatively huge population base poor survival rate, is still a threat in China, accounts for nearly half cases Fortunately, incidence mortality rates presented declining trend owing change individual life styles persistent efforts prevent from governments at all levels. <i>Helicobacter pylori</i> (<i>H. pylori</i>) infection, eating habits, smoking, history...
Hispidulin, an active component from Artemisia vestita, a traditional Tibetan medicinal plant, has been shown to possess anti-inflammatory and anti-oxidative activities. However, the functional role of hispidulin on tumor growth angiogenesis not elucidated. We found that significantly inhibited human pancreatic in xenograft mice when s.c. treated at dosage 20 mg/kg daily, this effect was accompanied with potent inhibition angiogenesis. When examining cytotoxicity HUVECs cancer cells vitro,...
Abstract Background and Aim Micro RNA s (mi s) are small noncoding molecules that control target gene expression implicated in the regulation of diverse cellular pathways. In our previous research, we have demonstrated mi R ‐224 was overexpressed liver cancer cells tissues, which an important factor cell migration invasion. This study aimed to further explore regulatory mechanism invasion cells. Methods A luciferase reporter assay used confirm HOXD 10 a direct ‐224. Quantitative reverse...
Uniportal subxiphoid video-assisted thoracoscopic (SVATS) surgery for major lung resections is a new approach, but clinical evidence lacking. The aim of this study was to examine our experience with the use uniportal approach in (VATS) and lymph node dissections. From October 2014 August 2015, 153 patients early-stage non-small-cell carcinoma (NSCLC) benign disease underwent VATS resections. Patients were placed lateral position 60–70° inclination, 4- 5-cm midline median or transverse...
We have experimentally discovered that in a nematic liquid crystal subjected to an ac electric field, the first convective structure at low frequencies is fact set of oblique rolls, contrary accepted picture. show it new with helical flow motion, and thus lower symmetry than usual normal rolls recovered high frequencies. Besides indicating limitations available theoretical models, these results clearly highest-symmetry corresponds rolls.
SMAD7 is a key inhibitor of transforming growth factor β (TGFβ) receptor signaling, which regulates the alteration cancer cell invasiveness through epithelial-mesenchymal conversion. Carboplatin commonly used drug in chemotherapy for non-small lung (NSCLC). Nevertheless, molecular mechanisms underlying its suppressive effects on NSCLC invasion are not completely understood. In current study, we addressed this question by analyzing microRNA-regulated SMAD7.We to treat lines. We performed...
Abstract Background The incidence rates of thyroid tumors and nodular goiter show an upward trend worldwide. There are limited reports on the risk perchlorate iodine tumors, but evidence from population studies is scarce, their impact function still uncertain. Therefore, objective this study was to investigate association with (NG), papillary microcarcinoma (PTMC), carcinoma (PTC) assess correlation between indicators. Methods A case–control consisting 184 pairs matched by gender age (±2...
<title>Abstract</title> Purpose To investigate the association and causality between physical activity hepatitis C virus (HCV) infection. Methods In this cross-sectional study, we conducted a bidirectional two-sample Mendelian Randomization (MR) analysis using data from GWAS database. The analytic population was divided into three categories based on infection outcomes, statistical differences were analyzed with covariates. Additionally, Restricted Cubic Spline (RCS) applied to examine...
Boston, as one of the most populated cities in United States, while being known for its rich history, humanities and culture, also faces significant challenges with crime. This paper presents research on critical factors that influence a possibility crime Boston UCR part 1 If applied to law enforcement agencies, distribution police resources can be more reasonable enable better urban security. We obtained dataset from Kaggle post, which was Crime Incident Report Police Department. By...
The article examines the philosophical foundations of civic identity, with an emphasis on its formation and strengthening in multinational states. It analyzes role identity ensuring social stability, national unity, harmonious interethnic interaction. study is based interdisciplinary approach, including analysis legal frameworks, sociological data, expert interviews. Special attention given to a three-dimensional approach enhancing among Tibetans China, covering political, emotional,...
Objective To investigate the association between ambient air pollution and stroke morbidity in different subgroups seasons. Methods We performed a time-series analysis based on generalised linear models to study short-term exposure–response relationships hospitalisations, conducted subgroup analyses identify possible sensitive populations. Results For every 10 µg/m 3 increase concentration of pollutants, across lag 0–3 days, relative risk hospitalisation was 1.029 (95% CI 1.013 1.045) for PM...
China is faced with heavy burdens caused by lung cancer, which has climbed to the top of both cancer incidence and mortality spectrums. The age-standardized rates have shown a trend gradual up-trends in last decades, while crude rise much quickly due aging population. Although improvement health care contributed better survival its prognosis still challenging. Apart from common risk factors such as tobacco use, air pollution, occupational hazards, some specific like Chinese-style cooking...
Type XI collagen (COL11A1) was reported to associate with malignancy in several cancer types, whereas its role lung is not fully understood. Therefore, the present study aimed explore expression level and biological of COL11A1 cells.Gene Expression Omnibus (GEO) database containing 6 tissues normal used identify potential aberrantly expressed genes. The COL11A1, apoptosis related genes, cell cycle genes migration associated at protein were evaluated by western blot mRNA determined real-time...