Zhen Wu

ORCID: 0000-0003-3587-1319
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Methane Hydrates and Related Phenomena
  • Earthquake Detection and Analysis
  • Seismic Waves and Analysis
  • Geophysics and Gravity Measurements
  • Ionosphere and magnetosphere dynamics
  • Astrophysics and Cosmic Phenomena
  • Solar and Space Plasma Dynamics
  • Systemic Lupus Erythematosus Research
  • Cardiac Imaging and Diagnostics
  • Lipoproteins and Cardiovascular Health
  • Cerebrovascular and Carotid Artery Diseases
  • Viral gastroenteritis research and epidemiology
  • Psoriasis: Treatment and Pathogenesis
  • Vitamin D Research Studies
  • Animal Virus Infections Studies
  • Spondyloarthritis Studies and Treatments
  • Acute Myocardial Infarction Research
  • Fibroblast Growth Factor Research
  • Cardiovascular Function and Risk Factors
  • Acupuncture Treatment Research Studies
  • Monoclonal and Polyclonal Antibodies Research
  • Redox biology and oxidative stress
  • Toxoplasma gondii Research Studies
  • interferon and immune responses
  • Health and Wellbeing Research

Third Affiliated Hospital of Sun Yat-sen University
2010-2025

Sun Yat-sen University
2010-2025

Sichuan Agricultural University
2024-2025

Ministry of Education of the People's Republic of China
2024

Jiangsu University
2024

First People's Hospital of Kunshan
2024

Purdue University West Lafayette
2020-2023

Philadelphia University
2014

University of Pennsylvania
2014

Fibroblast growth factor 21 (FGF-21) is a metabolic regulator with multiple beneficial effects on glucose homeostasis and lipid metabolism in animal models. The relationship between plasma levels of FGF-21 coronary heart disease (CHD) unknown.This study aimed to investigate the correlation serum patients disease. We performed logistic regression analysis relation CHD without diabetes hypertension. This was conducted Departments Endocrinology Cardiovascular Diseases at two University...

10.1371/journal.pone.0015534 article EN cc-by PLoS ONE 2010-12-29

Objective. The aim of this study was to assess the efficacy and safety golimumab in Chinese patients with active AS. Methods. Two hundred thirteen were randomized a 1:1 ratio receive either s.c. injections placebo from weeks 0 20 followed by 50 mg 24 48 (group 1, n = 105) or 2, 108), both every 4 weeks. Placebo crossover occurred at week 24, while early escape 16. primary endpoint an improvement least 20% Assessment SpondyloArthritis international Society (ASAS20) criteria 14. Major...

10.1093/rheumatology/keu132 article EN Lara D. Veeken 2014-04-11

Background: Extensive research has established obstructive sleep apnea (OSA) as a contributing factor to numerous cardiovascular and cerebrovascular diseases. However, whether OSA affects in-stent restenosis (ISR) after elective drug-eluting stenting is unclear. Therefore, the objective of this study was examine impact on ISR in patients with coronary heart disease (CHD) who underwent successful stent (DES) implantation. Methods: This retrospectively analyzed CHD successfully implantation...

10.31083/rcm25814 article EN cc-by Reviews in Cardiovascular Medicine 2025-01-15

Accurate prediction of cardiovascular disease (CVD) mortality is essential for effective treatment decisions and risk management. Current models often lack comprehensive integration key biomarkers, limiting their predictive power. This study aims to develop a model CVD-related using machine learning-based feature selection algorithm assess its performance compared existing models. We analyzed data from cohort 4,882 adults recruited between 1999 2004, followed up 20 years. After applying the...

10.1038/s41598-025-88790-y article EN cc-by-nc-nd Scientific Reports 2025-02-03

Avian reovirus (ARV), a double-stranded RNA virus, frequently induces immunosuppression in poultry, leading to symptoms such as irregular bleeding and spleen necrosis infected ducks. Since 2017, the morbidity mortality rates associated with ARV infection poultry have been on rise, progressively emerging significant viral disease impacting duck farming industry China. In our study, we collected embryo fibroblasts 18 h post-infection conducted transcriptome sequencing analysis. The analysis...

10.3389/fmicb.2025.1539903 article EN cc-by Frontiers in Microbiology 2025-02-05

The SYNTAX score is a semi-quantitative angiographic tool used to determine the extent and severity of coronary artery disease (CAD). Automatic computer-assisted measurement brachial-ankle pulse wave velocity (baPWV) reproducible valid method by which assess arterial stiffness. Limited information available for association between stiffness in CAD patient. We aim determined PWV assessed angiography score.321 subjects underwent both baPWV from 2010 2011. BaPWV was divided into tertiles....

10.5551/jat.13326 article EN cc-by-nc-sa Journal of Atherosclerosis and Thrombosis 2012-01-01

3D polymerase, also known as RNA-dependent RNA is encoded by all picornaviruses, and their structures are highly conserved. In the process of picornavirus replication, polymerase facilitates assembly replication complexes directly catalyzes synthesis viral RNA. The nuclear localization signal carried combined with its ability to interact other proteins, cellular indicate that noncatalytic role equally important in infections. Recent studies have shown has multiple effects on host cell...

10.3389/fimmu.2024.1365521 article EN cc-by Frontiers in Immunology 2024-04-02

The present study aimed to explore the correlation of atherogenic index plasma (AIP) with angiographic progression coronary artery disease (CAD). AIP was defined as base 10 logarithm ratio triglyceride high-density lipoprotein cholesterol concentration. extent lesion assessed by Gensini Score (GS) system and GS rate change per year >1 point. A total 896 patients suspected CAD who underwent computed tomography angiography twice at intervals >6 months were included. Baseline positively...

10.1177/00033197221080911 article EN Angiology 2022-03-01

Electrocardiogram (EKG) abnormalities are predictive of subsequent cardiovascular events. Cardiac involvement is common in systemic lupus erythematosus (SLE). We aimed to determine the prevalence EKG SLE patients and examine factors associated with machine learning approaches.Consecutive patients' records were retrieved from database hospital for cross-sectional study. Abnormal EKGs clinical significance grouped by presence tachyarrhythmias, atrioventricular block, nonspecific ST segment...

10.1002/acr.24612 article EN Arthritis Care & Research 2021-03-31

Duck plague (DP) is one of the contagious diseases caused by virus (DPV), which a serious threat to development duck farming. Us3 PKA-like protein kinase in alphaherpesvirus, can regulate biological functions many viral proteins, but whether regulates pUL48 has not been reported. In this paper, Western Blot, qRT-PCR, dual luciferase reporter system and Co-IP were used investigate relationship between Us3. The results showed that: (1) interacted with at 138-256aa through its DBD region. (2)...

10.1016/j.psj.2024.103498 article EN cc-by-nc-nd Poultry Science 2024-01-26

Background: Patients with ischemic stroke who have H-type hypertension are at an increased risk of recurrent stroke. The relationship between perception and lifestyle in these patients has not been fully explored. objective this study is to investigate perceptions lifestyles among hypertensive explore their relationships. Methods: A total 314 were divided according homocysteine (Hcy) level into the normal Hcy high group using convenience sampling. was further perceived or non-perceived based...

10.21037/apm-20-2012 article EN Annals of Palliative Medicine 2020-11-01

Lipoprotein(a)[Lp(a)] has been considered as an independent risk factor for coronary artery disease (CAD). The present study aimed to evaluate the association between baseline serum Lp(a) and CAD progression determined by angiographic score.A total of 814 patients who had undergone two or more computed tomography angiography at least 6 months apart were consecutively enrolled severity was Gensini score system. Patients stratified into groups according Lp(a)>300 mg/L ≤ 300 classified...

10.1002/clc.23718 article EN cc-by Clinical Cardiology 2021-08-25

To the Editor: Ischemic stroke remains a major cause of death and disability worldwide contributes to rising costs health care. Thrombolytic therapy with tissue plasminogen activator (tPA, alteplase) is beneficial for treatment acute ischemic stroke. However, only 40% 50% patients show significant improvement after treatment. In addition, use alteplase restricted because symptomatic intracranial hemorrhage (sICH) occurs in 1.7% 6.4% treated patients.[1] 25-hydroxyvitamin D (25(OH)D), which...

10.1097/cm9.0000000000000084 article EN cc-by-nc-nd Chinese Medical Journal 2019-02-06

Objective: To investigate the effects of combined acupuncture anesthesia and ropivacaine on postoperative analgesia neuro-related factors in patients undergoing chest surgery.

10.1080/00207454.2024.2346155 article EN International Journal of Neuroscience 2024-04-20

Lakes are vital landscape units with ecological, economic, and social characteristics, the studies related to lakes is thereby reaching up magnitude of 105 that cannot be analysed manually. However, in bibliometric, there limited methodology data regarding geographical distribution studied specific topics discussed research. There still a need for comprehensive methods combine lake morphology, local research topics. In this study, we assembled metadata from 58,024 peer-reviewed publications...

10.2139/ssrn.4823073 preprint EN 2024-01-01

Accumulating evidence indicated that apolipoprotein B (apoB) was the principal lipid determinant of coronary artery disease (CAD). Nevertheless, connection between apoB and angiographic progression CAD remained undetermined.Five hundred forty-four patients with twice computed tomography angiography experiences were enrolled. The Gensini scoring system used to assess progression. Incident defined as an annual change rate score > 1 point. predictive efficacy baseline levels for assessed using...

10.1186/s12944-023-01872-6 article EN cc-by Lipids in Health and Disease 2023-08-09

10.25582/data.2023-02.2747705/2356694 article EN OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) 2023-02-20

10.25582/data.2023-02.2746722/2356692 article EN OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) 2023-02-19

10.25582/data.2023-02.2744740/2356695 article EN OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) 2023-02-18

10.25582/data.2023-02.2746992/2356691 article EN OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) 2023-02-19

10.25582/data.2023-02.2749360/2356696 article EN OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) 2023-02-21

10.25582/data.2023-02.2748433/2356697 article EN OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) 2023-02-20
Coming Soon ...