A5059768209- Spondyloarthritis Studies and Treatments
- Rheumatoid Arthritis Research and Therapies
- Psoriasis: Treatment and Pathogenesis
- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Bone and Joint Diseases
- T-cell and B-cell Immunology
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Spine and Intervertebral Disc Pathology
- Monoclonal and Polyclonal Antibodies Research
- Dermatology and Skin Diseases
- Urticaria and Related Conditions
- Osteomyelitis and Bone Disorders Research
- Neurogenetic and Muscular Disorders Research
- Inflammatory mediators and NSAID effects
- Hematological disorders and diagnostics
- Hip disorders and treatments
- Immunodeficiency and Autoimmune Disorders
- Dermatological and Skeletal Disorders
- Musculoskeletal pain and rehabilitation
- Healthcare Systems and Technology
- Connective tissue disorders research
- Autoimmune Bullous Skin Diseases
- Scoliosis diagnosis and treatment
- Pneumocystis jirovecii pneumonia detection and treatment
University of Kansas Medical Center
2025
Case Western Reserve University
2014-2024
University School
1999-2024
Quaid-i-Azam University
2023
University of Utah
2023
Spondylitis Association of America
2023
Tris Pharma (United States)
2023
Moderna Therapeutics (United States)
2023
Institute of Business Management
2022
MetroHealth Medical Center
2008-2021
<h3>Objective:</h3> To validate and refine two sets of candidate criteria for the classification/diagnosis axial spondyloarthritis (SpA). <h3>Methods:</h3> All Assessment SpondyloArthritis international Society (ASAS) members were invited to include consecutively new patients with chronic (⩾3 months) back pain unknown origin that began before 45 years age. The first tested in entire cohort 649 from 25 centres, then refined a random selection 40% cases thereafter validated remaining 60%....
Abstract We compared the frequency of clinical features systemic lupus erythematosus (SLE) and determined survival in 113 patients with younger‐onset (age ⩾ < at diagnosis) 25 older‐onset disease ⩾55 diagnosis). The most striking difference was racial distribution; 59% younger were black, only 20% ( P 0.001). Major manifestations (including clinically evident renal disease, central nervous system involvement, cutaneous hemocytopenia) occurred similar both age groups. Antibodies to DNA...
Familial aggregation of fibromyalgia has been increasingly recognized. The goal this study was to conduct a genome-wide linkage scan identify susceptibility loci for fibromyalgia.
Typing for histocompatibility antigen (HLA)-B27 has been suggested as a clinically valuable diagnostic test ankylosing spondylitis and Reiter's syndrome, although some decry its use this purpose. Diagnoses can be made in most patients with these diseases on the basis of history, physical examination, roentgenographic findings. The B27 cannot used to screen an asymptomatic population detect should not thought routine test. We present probability graphs derived from Bayes' theorem, which show...
In a new series of RA patients the association with HLA-DR4 was again found to be highly significant. Also increased were DR4 associated antigens DRw53 and DQw3. Hybridization DQ-beta probe Bg1 II-digested DNA showed that variant DQw3, characterized by 4.3 kb fragment related serological specificity TA10, markedly among positive patients. HLA-DR1 also in appeared independent increase DR4. Although DR1 weaker, it observed both without RF. contrast, significantly only RF group patients, as...
Objective. The aim of this study was to assess the efficacy and safety golimumab in Chinese patients with active AS. Methods. Two hundred thirteen were randomized a 1:1 ratio receive either s.c. injections placebo from weeks 0 20 followed by 50 mg 24 48 (group 1, n = 105) or 2, 108), both every 4 weeks. Placebo crossover occurred at week 24, while early escape 16. primary endpoint an improvement least 20% Assessment SpondyloArthritis international Society (ASAS20) criteria 14. Major...
Objective Axial spondyloarthritis (axSpA) comprises both radiographic and non-radiographic disease. However, the paucity of specific objective measures for disease current classification criteria showing suboptimal specificity contribute to heterogeneity observed in clinical practice research. We used a historical cohort patients with axSpA assess sources heterogeneity. Methods The study involved 363 probands recruited from membership Swiss Ankylosing Spondylitis Patient Society....