A5108324428- Liver physiology and pathology
- Organ Transplantation Techniques and Outcomes
- Pancreatic function and diabetes
Southern Medical University
2024-2025
Guangdong Academy of Medical Sciences
2025
Guangdong Provincial People's Hospital
2025
Zhujiang Hospital
2024
Abstract The Leishmania homolog of receptors for activated C kinase (LACK) protein is derived from parasites L. major . polypeptide LACK 156–173 has been shown to confer protection against murine autoimmune arthritis. Fibroblast‐like synoviocytes (FLSs) play a pivotal role in the synovial invasion and joint destruction observed rheumatoid arthritis (RA). study reveals that 156‐173 can inhibit aggressive phenotype RA‐FLSs by restoring dysregulated fatty acid synthesis metabolism. In RA‐FLSs,...
This investigation aimed to evaluate the efficacy and safety of belimumab telitacicept in active systemic lupus erythematosus (SLE) explore potential predictors within a treat-to-target paradigm. 101 individuals were retrospectively enrolled at Guangdong Provincial People's Hospital between January 2021 December 2023, receiving either (n = 50) or 51) conjunction with standard therapy for more than 24 weeks. Key clinical endpoints evaluated, low disease activity state (LLDAS) as primary...
Hepatocyte transplantation is an effective treatment for end-stage liver disease. However, due to the limited supply of human hepatocytes, porcine hepatocytes have garnered attention as a potential alternative source. Nonetheless, traditional primary exhibit certain limitations in function maintenance and vitro proliferation. This study has discovered that by using histone deacetylase inhibitors (HDACi), can be successfully reprogrammed into progenitor cells with high proliferative...