A5101602443- Bone fractures and treatments
- Orthopedic Surgery and Rehabilitation
- Reconstructive Surgery and Microvascular Techniques
- Hip and Femur Fractures
- Shoulder Injury and Treatment
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Pelvic and Acetabular Injuries
- Trauma Management and Diagnosis
- Shoulder and Clavicle Injuries
- RNA modifications and cancer
- Bone Metabolism and Diseases
- Bone health and treatments
- Protein Kinase Regulation and GTPase Signaling
- Phytase and its Applications
- Cellular transport and secretion
- Bone and Joint Diseases
- Foot and Ankle Surgery
- Cancer-related molecular mechanisms research
- Orthopaedic implants and arthroplasty
Ningbo No.6 Hospital
2014-2023
The First People’s Hospital of Lianyungang
2019
Sepsis remains the primary cause of death in intensive care units and multiple long non-coding RNAs (lncRNAs) have been demonstrated to be dysregulated samples patients with sepsis. However, whether lncRNA-HOTAIR is involved etiology sepsis unclear. The aim present study was investigate role HOTAIR reveal associated mechanisms. A bioinformatics analysis dual-luciferase reporter assay performed evaluate interaction between miR-211, as well miR-211 IL-6R. An animal model established mice via...
Summary: The surgical treatment of distal tibial fractures is still challenging. purpose this study was to evaluate the clinical and radiographic results associated with use a precontoured femoral locking plate as an external fixator in treating fractures. From August 2011 October 2012, 28 patients were consecutively enrolled study. There 9 OTA 43.A1, 43.A2, 10 43.A3, including 21 closed 7 open placed on anteromedial aspect tibia fixator. All followed for average 16 months. mean duration 38...
To evaluate the feasibility and efficiency of one-stage external fixation by using locking plate in distal tibial fractures.In this non-control prospective study, 28 patients with fractures were included underwent plate. There 21 males 7 females, a mean age 43 years (19-63). According to AO/OTA fracture classification, there 9 cases Type A1, A2, 10 A3 fractures. close open The was placed on anteromedial aspect tibia 4-5 bicortical screws inserted both met- aphysis diaphysis. radiographic...
The traditional surgical treatment of proximal tibial metaphyseal fracture includes internal fixation with a plate or intramedullary nailing.Open reduction and often requires extensive soft-tissue Background: locking plates are used for closed fractures.The use as an external fixator is still controversial, particularly purpose this study to evaluate the results using femoral less invasive stabilization system (LISS) in fractures tibia. Methods:We prospectively evaluated 35 patients (26...
Previous research indicated that overexpression of miRNA-211 could promote colorectal cancer cell growth by targeting tumor suppressive gene Chromodomain-helicase-DNA-binding protein 5 (CHD5) in human colon (CC). Moreover, the function single-nucleotide polymorphism (SNP) located mature region miR-211 has not been investigated. In this study, we found SNP rs187960998 was involved occurrence CC acting as a suppressor mal-regulation its target CHD5.The genotype total 685 patients detected...
Segmental tibial fractures usually follow a high-energy trauma and are often associated with many complications. The purpose of this report is to describe the authors' results in treatment segmental supercutaneous locking plates used as external fixators. Between January 2009 March 2012, total 20 patients underwent plating (supercutaneous plating) using less-invasive stabilization system plate (Synthes, Paoli, Pennsylvania). Six were closed 14 open (6 grade IIIa, 2 IIIb, 4 II, I, according...
Minimally invasive plate osteosynthesis (MIPO) has become a widely accepted technique to treat distal tibial fractures. Recently, the novel application of locking used as an external fixator (supercutaneous plating) was introduced for management open fractures and infected nonunions even adjunct in distraction osteogenesis, which is considered another less method. The aim this study compare results supercutaneous plating with closed reduction minimally treatment Forty-eight matched patients...
To explore the effect of miRNA-143 on osteoclast formation and provide new ideas for treatment osteoporosis.Mice macrophage lines RAW264.7 cells after transfection were divided into four groups: control group, RANKL combined with miR-143 mimics group miR-NC group. TARCP staining was used to observe formation. The expression RANK, TRAF6 NFATc-1 in upstream pathway detected by real-time quantitative PCR (RT qPCR) Western blotting (WB). binding TNFRSF11A double Luciferase Reporter Analysis....
Purpose: The purpose of this study was to clinically compare the single-incision and dual-incision approaches for treatment distal tibial fibular fractures. Methods: In total, 93 patients were enrolled, mean follow-up 15 months (range 12–19 months). treated open reduction internal fixation randomly classified into two groups based on approach used: 45 using (group 1) 48 2). these groups, operation time, discharge postoperative complications, ankle function evaluations (Olerud–Molander Ankle...
To investigate the efficacy of posterior axillary approach internal fixation for Ideberg Ⅰa andⅡ glenoid fractures.From December 2018 to September 2021, 9 patients with lower part fractures were treated by approach, including 3 males and 6 females, aged from 50 78 years old. All closed fractures. According type scapular fracture was in cases Ⅱ cases. AP lateral X-ray films scapula taken at 6, 12 weeks months postoperatively. Constant-Murley disabilities arm shoulder hand (DASH), other...
Objective: To explore the clinical effect of free transplantation thoracodorsal artery perforator flap in reconstructing large scar on facial subunit. Methods: From April 2014 to March 2018, 7 patients with were admitted Ningbo NO.6 Hospital, including 3 males and 4 females, aged from 31 49 years, frontal involvement chin neck. Color Doppler ultrasound was used for positioning perforating vessel, resection performed according principle subunit repair. The wound area 8 cm×6 cm-21 cm×8 cm,...