- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Orthopedic Surgery and Rehabilitation
- Bone fractures and treatments
- Orthopedic Infections and Treatments
- Hip disorders and treatments
- Pelvic and Acetabular Injuries
- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Fluid Dynamics and Turbulent Flows
- Heat Transfer Mechanisms
- 3D Printing in Biomedical Research
- Biomarkers in Disease Mechanisms
- Foot and Ankle Surgery
- Spaceflight effects on biology
- Bone Metabolism and Diseases
- Lower Extremity Biomechanics and Pathologies
- Parkinson's Disease Mechanisms and Treatments
- Tissue Engineering and Regenerative Medicine
- Advanced Welding Techniques Analysis
- Axon Guidance and Neuronal Signaling
- Shoulder and Clavicle Injuries
- Amyotrophic Lateral Sclerosis Research
- Bone and Joint Diseases
- Genetics, Aging, and Longevity in Model Organisms
Ningbo No.6 Hospital
2007-2025
Shanghai Jiao Tong University
2005-2024
Shanghai Ninth People's Hospital
2019-2024
East China University of Science and Technology
2019
Zhejiang University
2018
Southwest Jiaotong University
2015-2018
École Polytechnique Fédérale de Lausanne
2017
Weill Cornell Medicine
2016
Cornell University
2016
University of Toledo Medical Center
2011
Investigating the clinical efficacy of treating dorsally displaced distal radial double-column Die-punch fractures using a dorsal approach external fixator combined with Kirschner wires. Retrospectively analyzed data 15 patients treated an wire between July 2020 and January 2023. There were 10 males 5 females;6 cases on left side 9 right;age ranged from 22 to 76 years old. Recorded preoperative final follow-up Cooney wrist function scores for patients. The fracture healing time, occurrence...
Flow regimes in a cross-shaped reactor with square cross sections of two inlets and outlets were investigated at 20 ≤ Re 500, where is the Reynolds number. Visualization images on obtained by planar laser induced fluorescence, several flow identified. Results show that, increasing Re, symmetric segregated flow, steady engulfment an unsteady emerge turns. First, formed < 48. At 48 300, becomes asymmetric spiral vortex center outlet chamber, which called flow. 300 400, occurs periodic...
Abstract This study follows our previous report (Zhang et al., Phys. Fluids, vol. 31, 2019, 034105) by describing the formation and evolution of engulfment flow in cross‐shaped channel. First, regimes were studied planar laser induced fluorescence (PLIF). Results show a spiral vortex center chamber appearance well‐mixed zone inside vortex. Second, we proposed novel experimental method to analyze residence time fluid chamber, discover an unexpected trapping region zone. There is almost no...
To evaluate accuracy of an innovative "Skywalker" system, a newly designed, robot-assisted operation system for orthopaedics via clinical trial at knee joint. We conducted prospective analysis the data 31 patients who underwent total arthroplasty assisted by robot (Microport, Suzhou, China) from June 2020 to January 2021. Five male and 26 female aged 69.68 ± 6.11 years (range: 57-79 years) were diagnosed with osteoarthritis indicated surgery. The surgical robotic was adopted make...
Background: Intra-articular calcaneal fractures are more likely to suffer consequences in terms of pain and disability. Many studies have suggested that operative treatment for these may result better outcomes than nonoperative treatment. The metallic screws plates among the most common alternatives stabilize fractures. However, complications plating not uncommon. Complications such as infection, poor wound healing, soft tissue irritation exist. With advent bioabsorbable screws, many reports...
Calcium phosphate silicate (Ca5(PO4)2SiO4 or CPS) is a promising bioceramic for bone grafting. Iron (Fe) trace element in the human body that has been reported to enhance mechanical strength of CPS ceramics. However, exact biofunctions Fe, combined with another element, viz. silicon (Si), and optimal dose Fe addition must be further investigated. In vitro: morphology, structure cell adhesion were observed by SEM; ability promote osteogenic differentiation mineralization was explored ALP...
Summary: The surgical treatment of distal tibial fractures is still challenging. purpose this study was to evaluate the clinical and radiographic results associated with use a precontoured femoral locking plate as an external fixator in treating fractures. From August 2011 October 2012, 28 patients were consecutively enrolled study. There 9 OTA 43.A1, 43.A2, 10 43.A3, including 21 closed 7 open placed on anteromedial aspect tibia fixator. All followed for average 16 months. mean duration 38...
Osteoporosis is a bone disease that associated with decrease in mineral density, deterioration of microarchitecture and increased fracture risk. Currently, available treatments mainly focus on either inhibiting osteoclast function, such as administration bisphosphonate, calcitonin, oestrogen, selective oestrogen receptor modulator so on, or stimulating osteoblasts, parathyroid hormone, to improve mass skeletal microarchitecture. However, there no option completely satisfactory because the...
To evaluate the feasibility and efficiency of one-stage external fixation by using locking plate in distal tibial fractures.In this non-control prospective study, 28 patients with fractures were included underwent plate. There 21 males 7 females, a mean age 43 years (19-63). According to AO/OTA fracture classification, there 9 cases Type A1, A2, 10 A3 fractures. close open The was placed on anteromedial aspect tibia 4-5 bicortical screws inserted both met- aphysis diaphysis. radiographic...
The traditional surgical treatment of proximal tibial metaphyseal fracture includes internal fixation with a plate or intramedullary nailing.Open reduction and often requires extensive soft-tissue Background: locking plates are used for closed fractures.The use as an external fixator is still controversial, particularly purpose this study to evaluate the results using femoral less invasive stabilization system (LISS) in fractures tibia. Methods:We prospectively evaluated 35 patients (26...
Aseptic loosening caused by wear particles is one of the common complications after total hip arthroplasty. We investigated effect recombinant protein ephB4-Fc (erythropoietin-producing human hepatocellular receptor 4) on particle-mediated inflammatory response. In vitro, ephrinB2 expression was analyzed using siRNA-NFATc1 (nuclear factor activated T-cells 1) and siRNA-c-Fos. Additionally, we used Tartrate-resistant acid phosphatase (TRAP) staining, bone pit resorption, Enzyme-linked...
Objective To compare rapid prototyping technology (RP tech) in revision total hip arthroplasty (RTHA) with traditional examination methods and to see how they are different evaluating acetabular anatomy designing surgical procedure. Methods From February 2014 March 2018, 43 RTHA patients complex acetabulum defects were enrolled this prospective study regardless of age or gender. Incomplete unclear data excluded. Three types radiographic performed on each patient before the surgery. Four...
To assess the changes in alignment of ipsilateral knee joint after total hip arthroplasty (THA) for patients with developmental dysplasia (DDH).Thirty-four DDH (38 hips) who underwent THA between February and December 2008 were included study: 4 men 30 women a mean age 56.2 years. According to Crowe classification, 11 grade I, 12 II, 9 III, 6 IV. Computed tomography scans performed from anterior superior iliac spine tibial tubercle before surgery at last follow-up. Femoral anteversion angle,...
Pore interconnectivity is a key parameter for bone tissue engineering scaffolds, which controls penetration of body fluid with proteins and cells, ingrowth.The present study investigated the porous characteristics hydroxyapatite (HA) scaffolds prepared via three processes (HA sphere packing, wax sphere-leaching HA fiber aggregation) by micro-computed tomography (μCT) from following procedures: (1) modeling structure image reconstruction; (2) analysis porosity along longitudinal direction;...
This study aimed to investigate the optimal level of femoral neck for measuring anteversion predict postoperative stem in Crowe type I developmental dysplasia hip.This retrospective analyzed 108 hips that underwent THA between January 2016 and December 2017, including 70 women 19 men with a mean age 63.08 ± 9.13 (range, 41-83) years. The single-wedge was used 37 hips, double-wedge 71 hips. Computed tomography scans were performed pre- post-operation. Femoral at six levels proximal femur...
Abstract Background Precise evaluation of the hip abductor and adductor muscles function in total arthroplasty (THA) patients during gait could help prevent postoperative complications optimize rehabilitation training program. The purpose this study was to elucidate effects THA on muscle lengths moment arms vivo gait. Methods Ten unilateral received CT scans dual fluoroscopic imaging for kinematics insertions were digitized 3D model determination their dynamic lines action arms. Changes...
Background Preoperative evaluation of femoral anteversion to predict postoperative stem aids the selection an appropriate prosthesis and optimizes combined in total hip arthroplasty (THA) for developmental dysplasia (DDH). The conventional prediction methods are based on measurement at location head and/or neck. However, varied differences between were demonstrated. This study investigated predictive role a new method principle sagittal three‐point fixation. Methods From January 2017...
Abstract Background The crural index, a fundamental property of the human skeletal system, is ratio total length tibia to that femur. This study aimed investigate correlation between index and knee osteoarthritis (OA). Methods observational cross-sectional included patients with preoperative weight-bearing full-length radiographs who were divided into two groups according Kellgren–Lawrence grading system. After rigorous screening based on inclusion exclusion criteria, 92 125 in control OA...
In the complex process of wound healing, oleogels (OG) are suitable as primary component dressing materials, but they cannot meet diverse requirements at different healing stages. this study, a new kind carbon dots (CrCi‐CDs) prepared by carbonizing human hair, exhibits excellent hemostatic, antibacterial, anti‐inflammatory, and pro‐angiogenic properties thus supports various stages effectively. Such CrCi‐CDs incorporated into OG to produce CrCi‐CD/OG composite material with enhanced...
The genome of the nematode Caenorhabditis elegans shows far-reaching similarities to that humans. C. is therefore considered as a powerful model organism in biological research related humans, for instance study human diseases. Such studies are often based on high-resolution imaging dynamic processes worm body tissues, requiring reliable immobilization nematodes. However, conventional methods may strongly affect physiological animal. Here, we report new approach on-chip nematodes, taking...