Aparna Shukla

ORCID: 0000-0002-6825-8644
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About
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Research Areas
  • Anesthesia and Pain Management
  • Anesthesia and Sedative Agents
  • Nausea and vomiting management
  • Airway Management and Intubation Techniques
  • Cardiac, Anesthesia and Surgical Outcomes
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Spine and Intervertebral Disc Pathology
  • Ovarian function and disorders
  • Sepsis Diagnosis and Treatment
  • Intensive Care Unit Cognitive Disorders
  • Anesthesia and Neurotoxicity Research
  • Mechanical Circulatory Support Devices
  • Music Therapy and Health
  • Shoulder Injury and Treatment
  • Spinal Hematomas and Complications
  • Intestinal and Peritoneal Adhesions
  • Diverse Music Education Insights
  • Birth, Development, and Health
  • Teratomas and Epidermoid Cysts
  • Stroke Rehabilitation and Recovery
  • Head and Neck Surgical Oncology
  • Infectious Encephalopathies and Encephalitis
  • Respiratory Support and Mechanisms
  • Monoclonal and Polyclonal Antibodies Research

King George's Medical University
2021-2025

Lemuel Shattuck Hospital
2025

B.J. Medical College
2025

Fistulacure
2024

All India Institute of Medical Sciences Raipur
2022

North Florida/South Georgia Veterans Health System
2021

University of Florida
2020-2021

Florida College
2021

Integral University
2012-2016

Institute of Medical Sciences
2012-2016

Background Laryngoscopy and tracheal intubation (L&I) the fixation of skull-pin head-holders are associated with various sympathetic stimuli leading to hemodynamic changes. These changes may lead myocardial ischemia, brain edema, an increase in intracranial pressure, or hemorrhage. Many drugs have been used different combinations attenuate responses L&I insertion. The aim this study was compare efficacy intranasal (IN) dexmedetomidine intravenous (IV) attenuating holders patients undergoing...

10.7759/cureus.76980 article EN Cureus 2025-01-05

Abstract Background TL1A blocking antibodies have demonstrated promising clinical remission rates in patients with inflammatory bowel disease (Sands B et al, NEJM 2024). promotes inflammation through binding to a single receptor, DR3. There are no known signaling ligands for DR3 aside from TL1A. Whereas is transiently expressed by antigen presenting and endothelial cells at sites of active the small large intestine, constitutively lymphoid peripheral blood, throughout GI tract both inflamed...

10.1093/ecco-jcc/jjae190.0072 article EN Journal of Crohn s and Colitis 2025-01-01

Background: Laparoscopic cholecystectomy nowadays is the preferable approach over open because of early recovery and lower rate complications. However, some undesirable effects, such as shoulder pain, which has an incidence about 12–60% after laparoscopic cholecystectomy, can affect patients. Aims Objectives: To study efficacy a pulmonary recruitment maneuver intraperitoneal bupivacaine in combination for reducing pain following cholecystectomy. Materials Methods: This randomized comparative...

10.71152/ajms.v16i3.4373 article EN cc-by-nc Asian Journal of Medical Sciences 2025-03-01

Background Endotracheal intubation in the intensive care unit (ICU) is often a risky procedure due to emergency situation, unstable condition of patient, and technical problems such as inadequate positioning. Several new techniques, video laryngoscopy, have been developed recently improve success rate first-pass intubations reduce complications. We conducted this study compare non-channeled reusable laryngoscope BPL VL-02 (manufactured by Medical Technologies, Bangalore, India) with...

10.7759/cureus.40716 article EN Cureus 2023-06-21
Anindya Mukherjee Gaurav Kumar Alka Turuk Ashish Bhalla Thrilok Chander Bingi and 95 more Pankaj Bhardwaj Tridip Dutta Baruah Sumit Mukherjee Arunansu Talukdar Yogiraj Ray Mary John J R Khambholja Abhishek Patel Sourin Bhuniya Rajnish Joshi Geetha R. Menon Damodar Sahu Vinaya Rao Balram Bhargava Samiran Panda Prabhakar Mishra Yachana Panchal Lokesh Kumar Sharma Ashwini Agarwal G. D. Puri Vikas Suri Kamal Singla R Mesipogu Vinaya Sekhar Aedula Mohammed Ayaz Mohiuddin Deepak Kumar Suman Saurabh Sanjeev Misra Pankaj Kumar Kannauje Ajit Kumar Aparna Shukla Anirban Pal S. Chakraborty Moumita Dutta TusharKanti Mondal S Chakravorty Bappaditya Bhattacharjee Sharanya Paul Dhriti Majumder Sanjay Chatterjee Ajay Abraham Diana Grace Varghese Maria Thomas Nehal Shah Maitri M. Patel Sanskruti Madan Anita Desai M L Kala Yadhav R Madhumathi Gupta Chetna Utkarsh Ojha R R Jha Ajit Kumar Ashish Pathak Arvind Sharma M Purohit Lalatendu Sarangi M. E. A. Rath Arti Shah Manoj Kumar L. Prakash Patel Navin Dulhani Simmi Dube Jyotsna Shrivastava Ankit Mittal Lipilekha Patnaik Jayaprakash Sahoo Sanjay Sharma V K Katyal Ashima Katyal Neha Yadav Rashmi Upadhyay Sharad Srivastava Alok Srivastava Nilay Suthar Nitin Shah Kruti Rajvansh Hemang Purohit Payal Mohapatra Manoj Kumar Panigrahi Saurabh Saigal Anil Khurana Manisha Panchal Mayank Anderpa Dharmesh Patel Veeresh.B. Salgar Santosh Algur Rupshikha Choudhury Madhumathi Rao D Nithya B. K. Gupta Bhuvnesh Kumar Jitendra Gupta Sudhir Bhandari Ashish Agrawal

This study aims to describe the demographic and clinical profile ascertain determinants of outcome among hospitalized coronavirus disease 2019 (COVID-19) adult patients enrolled in National Clinical Registry for COVID-19 (NCRC).NCRC is an on-going data collection platform operational 42 hospitals across India. Data NCRC between 1st September 2020 26th October 2021 were examined.Analysis 29 509 hospitalized, [mean (SD) age: 51.1 (16.2) year; male: 18 752 (63.6%)] showed that 15 678 (53.1%)...

10.1093/qjmed/hcac202 article EN public-domain QJM 2022-08-31

Subarachnoid block in patients with kyphoscoliosis always present a unique challenge to the anesthesiologist owing deformity of spine. The asymmetry bilateral spread local anesthetic has been reported earlier. We case report poliomyelitis patient fracture femur (left) thoracolumbar posted for open reduction internal fixation. Anesthesia planned this was subarachnoid modified paramedian approach which resulted unilateral sensory block.

10.4103/0975-2870.194226 article EN cc-by-nc-sa Medical Journal of Dr D Y Patil University 2016-01-01

Context: Regional anesthesia has emerged as one of the preferred and convenient modes for intra- post-operative management owing to its advantage not interfering with metabolic functions, better tolerability, decrease in reflex activity. In recent years, ropivacaine increasingly replaced bupivacaine a local anesthetic because similar analgesic properties, lesser motor blockade, decreased propensity cardiotoxicity. Neuraxial adjuvant such clonidine used epidural offers by augmenting effect...

10.4103/0259-1162.186601 article EN Anesthesia Essays and Researches 2016-07-25

Introduction Listening to music is a safe and low-cost way reduce preoperative anxiety among patients, but more research needed evaluate its effectiveness fully. Aims The aim of the study identify effect intraoperative therapy on visual analogue scale for (VASA) scores (VASA 1 VASA 2) patient satisfaction score (PSS) perioperatively. Methods In 188 patients aged 40-70, those in group A (94 patients) listened pre-approved during their surgery abdominal hysterectomy, while B did not. Both...

10.7759/cureus.39519 article EN Cureus 2023-05-26

Introduction: High incidences of Buerger's disease (43-62%) in India draw our attention towards available treatment modalities such patients. Patients with this are severe pain and agony. Pain relief by any means remains first foremost priority patients if patient is able to sleep even one free night it a boon for the The purpose study was test hypothesis that lumber sympathetic block relieves ischemic limb disease. Aims Objectives: To effect chemical on visual analog score (VAS) walking...

10.4103/0970-5333.128888 article EN cc-by-nc-sa Indian Journal of Pain 2014-01-01

Context: Clinical need for a nondepolarizing agent with rapid onset time and brief duration of action has led to the development rocuronium bromide. Aims: The aim this study was evaluate optimal dose bromide intubation compare time, action, intubating conditions, hemodynamic effects two doses Settings Design: A prospective, randomized, double-blind study. Materials Methods: All patients were divided in fashion into groups twenty each. Group I received 0.6 mg/kg intravenously intubated at 60...

10.4103/0259-1162.179308 article EN Anesthesia Essays and Researches 2016-01-01

Introduction: Postoperative period after panhysterectomy is very painful as there too much tissue handling. In the practice of regional anesthesia neuraxial, opioids have been used extensively an adjuvant to bupivacaine enhance potency and duration sensory motor block produced by with satisfactory results. However, delayed respiratory depression has prompted further research develop nonopioid analgesics. This study was undertaken assess degree postoperative analgesia provided low dose 50 μg...

10.4103/0259-1162.186610 article EN Anesthesia Essays and Researches 2016-07-25

Introduction Characterized by a range of symptoms including irregular menstrual cycles, hirsutism, and infertility, polycystic ovarian syndrome (PCOS) also poses substantial metabolic challenges. Among these, dyslipidemia obesity are particularly concerning due to their long-term implications for cardiovascular health. The present study explores the intricate relationship between lipid profile body mass index (BMI) in patients with PCOS presenting Department Obstetrics Gynaecology, King...

10.7759/cureus.63251 article EN Cureus 2024-06-26

Introduction Insulin resistance is a fundamental factor in the pathogenesis of polycystic ovarian syndrome (PCOS) and has been found to mediate close association with obesity dyslipidemia. While anti-diabetic anti-inflammatory properties fenugreek seed extracts have demonstrated, research on its anti-hyperlipidemic still novice stage, inconclusive evidence. The present study assessed impact rich furostanolic saponins (Furocyst) lipid profiles across different categories body mass index (BMI)...

10.7759/cureus.74571 article EN Cureus 2024-11-27

The technique of Cervical Epidural Anesthesia (CEA) was first described by Dogliotti in 1933 for upper thoracic procedures. Administration local anesthetic into cervical epidural space results anesthesia the neck, extremity, and region. CEA provides high-quality analgesia above dermatomes and, at same time, it has favorable effect on hemodynamic variable blocking sympathetic innervation heart. is not practiced routinely because its potential complications. We selected this excision giant...

10.4103/0259-1162.94781 article EN Anesthesia Essays and Researches 2011-01-01

Despite advances in modern medicine, sepsis remains a complex syndrome that has been associated with significant morbidity and mortality. Multiple organ failure leads to high mortality morbidity. About 28 - 50% deaths have reported patients sepsis. The number of is increasing, considerable burden on healthcare facilities. Various factors leading rise the incidence are (1) Improvement diagnostic procedures (2) Increase immunocompromised taking treatment for various autoimmune disease,...

10.4103/0019-5049.72637 article EN cc-by-nc-sa Indian Journal of Anaesthesia 2010-01-01

Sir, In the previous publication in Indian Journal of Anesthesia, role human recombinant activated protein C sepsis and severe has been discussed.[1] Initially, there was great confusion regarding use (APC) sepsis. PROWESS (recombinant world wide evaluation sepsis) trial[2] conducted July 1998 a multi-center, randomized, double blind, placebo-controlled trial 1690 patients with Results clearly indicated that one every five who would have died saved Drotrecogin alfa treatment, added to best...

10.4103/0019-5049.104597 article EN cc-by-nc-sa Indian Journal of Anaesthesia 2012-01-01

10.4103/0019-5049.63646 article EN cc-by-nc-sa Indian Journal of Anaesthesia 2010-01-01

Background: Recently, opoids are linked with cancer recurrence. Duloxetine hydrochloride (DH), an anxiolytic may reduce total opoid requirement after surgery. Aims: We assessed the efficacy of a single dose DH in reducing morphine open radical cholecystectomy. also calculated Visual Analog Scale (VAS) score, patient satisfaction score (PSS), and time taken to use first rescue analgesic. Setting Designes: This is prospective, randomized, double blind, controlled study conducted patients aged...

10.4103/aer.aer_75_22 article EN Anesthesia Essays and Researches 2022-07-01

Background: Thoracotomy is associated with various hemodynamics consequences that are influenced by the position of patient's body on operation Table and metabolic functions lungs. Dexmedetomidine an alpha-2 agonist sedative-analgesic inhibits endogenous norepinephrine release has been used in studies to maintain intraoperative hemodynamic stability. Aim: To evaluate effect infusion during thoracic surgery. Methods: The selected patients were randomly allocated two groups (39 each group)...

10.5530/jcram.1.1.2 article EN cc-by-nc-nd Journal of Clinical Research and Applied Medicine 2021-12-25

Encapsulated peritoneal sclerosis (EPS) is a rare but known complication of dialysis (PD) therapy in patients with end-stage renal disease (ESRD). It commonly manifests insidiously recurrent intestinal obstruction and malnutrition, worsening over time. We report an ESRD patient on PD for six years presenting acute obstruction, bowel hernia, ischemia, hemodynamic instability. CT abdomen revealed thickening walls colon ileum the right lower quadrant, signs small obstruction. Patient underwent...

10.7759/cureus.12934 article EN Cureus 2021-01-27

Sir, Spinal anesthesia is preferred for the caesarean sections safety and ease. Use of Qiuncke type small bore spinal needle recommended.[1] Through this letter, we are highlighting an unusual very rare mid-shaft defect detected accidentally while injecting drug. A 26 G mm × 9.0 (Becton Dickinson) was inserted at L2-3 interspace anesthesia. The subarachnoid space easily encountered. Clear, fluid observed in hub with removal stellate. We had started 0.5% hyperbaric bupivacaine through...

10.4103/1658-354x.144103 article EN cc-by-nc-sa Saudi Journal of Anaesthesia 2014-01-01

Background: Spinocerebellar ataxia 17 (SCA17) is a rare autosomal dominant trinucleotide disorder. There are no effective therapies for addressing the clinical symptoms of SCA17. Case report: We describe 46-year-old male who presented with generalized dystonia and focal arm tremors manifesting during adolescence. He underwent bilateral globus pallidus (GPi) DBS surgery that led to notable improvements in tremor symptoms, impacting his quality life. At time surgery, he did not show cerebellar...

10.3389/dyst.2023.11363 article EN cc-by Dystonia 2023-06-30
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