- Nanoplatforms for cancer theranostics
- Cancer Immunotherapy and Biomarkers
- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- Circular RNAs in diseases
- Advanced Nanomaterials in Catalysis
- Single-cell and spatial transcriptomics
- Wireless Signal Modulation Classification
- Alkaloids: synthesis and pharmacology
- Cancer Genomics and Diagnostics
- Lymphoma Diagnosis and Treatment
- Immune cells in cancer
- RNA Research and Splicing
- Ocular Oncology and Treatments
- Graphene and Nanomaterials Applications
- Wireless Communication Security Techniques
- Lung Cancer Treatments and Mutations
- Chronic Lymphocytic Leukemia Research
- Quantum Dots Synthesis And Properties
- Ocular Surface and Contact Lens
- Gene expression and cancer classification
- Immunotherapy and Immune Responses
- Chaos-based Image/Signal Encryption
- Nanocluster Synthesis and Applications
- Biochemical and Structural Characterization
University of South China
2022-2025
Zhejiang University
2024
First Affiliated Hospital Zhejiang University
2024
First Affiliated Hospital of University of South China
2023
PLA Army Engineering University
2023
Xiamen University
2022
Harbin Medical University
2021
Metal-organic frameworks (MOFs) have attracted significant research interest in biomimetic catalysis. However, the modulation of activity MOFs by precisely tuning coordination metal nodes is still a challenge. Inspired metalloenzymes with well-defined structures, series containing halogen-coordinated copper (Cu-X MOFs, X = Cl, Br, I) are employed to elucidate their structure-activity relationship. Intriguingly, experimental and theoretical results strongly support that halogen atoms directly...
Abstract Spatially resolved transcriptomics technologies potentially provide the extra spatial position information and tissue image to better infer cell–cell interactions (CCIs) in processes such as homeostasis, development, disease progression. However, methods for effectively integrating multimodal data CCIs are still lacking. Here, authors propose a deep learning method features through co‐convolution, called SpaGraphCCI, integrate from different modalities of SRT by projecting gene...
Triple-negative breast cancer (TNBC) is a significant cause of patient morbidity. The exactly pathobiological features this condition has yet to be completely elucidated.Breast data obtained from Cancer Genome Atlas (TCGA) database were evaluated for lncRNA SNHG6 expression. Normal human epithelial cell line (MCF-10A) and other lines (BT-549, MDA-MB-231, Hs 578t, ZR-75-30, SK-BR-3, MCF-7) also assessed expressions. Cellular proliferative ability was with colony formation CCK-8 assays. cells...
Breast cancer represents the number one cause of cancer-associated mortality globally. The most aggressive molecular subtype is triple negative breast (TNBC), which limited therapeutic options are available. It well known that prognosis and tumor sensitivity toward immunotherapy dictated by microenvironment. gene expression profiles were extracted from METABRIC dataset two TNBC clusters displaying unique immune features identified. Activated cells formed a large proportion in high...
Uveal melanoma (UVM) is the most common primary intraocular malignancy in adults. Epithelial-mesenchymal transition (EMT) an essential regulator of UVM's immune microenvironment. However, precise role EMT UVM remains to be explored and development a related treatment strategy urgently needed. Multiomics data clinical information for TCGA-UVM were used identify subtypes analyze their regulatory microenvironment UVM. A machine-learning method based on identified was utilized construct...
With the rapid development of communication business requirements, wireless plays a more and important role in people's daily life. At same time, information transmission security has attracted attention. Compared with traditional technology, physical layer security, which can improve using technologies on layer, opened up new direction for improving security. Based modulation mapping relationship QAM (Quadrature Amplitude Modulation) constellation consistency requirement rules between...