A5046794448- Advanced X-ray Imaging Techniques
- X-ray Spectroscopy and Fluorescence Analysis
- Advanced Electron Microscopy Techniques and Applications
- Advanced X-ray and CT Imaging
- Crystallography and Radiation Phenomena
- Laser-Plasma Interactions and Diagnostics
- Medical Imaging Techniques and Applications
- Nuclear Physics and Applications
- Advancements in Photolithography Techniques
- High-pressure geophysics and materials
- Optical measurement and interference techniques
- Advanced Surface Polishing Techniques
- Digital Holography and Microscopy
- Electron and X-Ray Spectroscopy Techniques
- Integrated Circuits and Semiconductor Failure Analysis
- Ion-surface interactions and analysis
- X-ray Diffraction in Crystallography
- Organometallic Complex Synthesis and Catalysis
- Superconducting Materials and Applications
- Thin-Film Transistor Technologies
- Bone Metabolism and Diseases
- Non-Destructive Testing Techniques
- Silicon and Solar Cell Technologies
- Optical Systems and Laser Technology
- Synthetic Organic Chemistry Methods
Toranomon Hospital
2025
Tohoku University
2016-2024
SPring-8
2001-2023
Japan Synchrotron Radiation Research Institute
2001-2022
RIKEN Center for Advanced Photonics
2022
University of Hyogo
2008-2017
Japan Science and Technology Agency
2016
NTT (Japan)
2011
Nihon University
2004-2005
Hyogo University
2005
A microfocusing experiment for hard X-rays has been performed to evaluate the performance of Fresnel zone plate optics. tantalum with an outermost width 50 nm and a thickness 0.5 µm fabricated by electron-beam lithography. The focused beam size measured knife-edge scan is 58 in full-width at half-maximum first-order diffraction X-ray energy 8 keV. It can be concluded that this nearly diffraction-limited resolution region. efficiency 5% spot using third-order focus approximately 30 nm.
This study focused on exploring the relationship between antimicrobial use indicators, including modified antibiotic heterogeneity index (mAHI), and carbapenem susceptibility in Pseudomonas aeruginosa. Survey-based observational conducted across multiple facilities. Public community hospital institutions. survey was 15 hospitals Japan. Indicators, such as defined daily doses (DDDs), days of therapy (DOTs), (AHI), mAHI, were analyzed for P. aeruginosa using Spearman's rank correlation. The...
Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Twitter Facebook Reddit LinkedIn Tools Reprints and Permissions Cite Search Site Citation Yoshio Suzuki, Kentaro Uesugi, Naoki Takimoto, Tomoki Fukui, Kohki Aoyama, Akihisa Takeuchi, Hidekazu Takano, Naoto Yagi, Tetsuro Mochizuki, Shunji Goto, Kunikazu Takeshita, Sunao Takahashi, Haruhiko Ohashi, Yukito Furukawa, Tohru Ohata, Tomohiro Matsushita, Yasuhide Ishizawa, Hiroshi Yamazaki, Makina Yabashi,...
A circular multilayer zone plate (MZP) was fabricated and its focusing performance evaluated using 20-keV x-rays. MoSi(2) Si layers were alternately deposited by DC magnetron sputtering on a wire core; all the interfaces satisfied Fresnel condition. The measured line spread function converted to point tomographic reconstruction. results suggest that MZP has potential realize diffraction-limited resolving power, which is calculated be 35 nm diffraction integral. Furthermore, scanning...
Under the JST-ERATO project in progress to develop X-ray and neutron phase-imaging methods together, recent achievements have been selected reviewed after describing merit principle of phase imaging method. For imaging, developments four-dimensional tomography microscopy at SPring-8, Japan are mainly presented. an approach combination with time-of-flight method developed J-PARC, is described description new Gd grating fabrication.
Since 2020, synchrotron radiation facilities in several Asia-Pacific countries have been collaborating a major project called "SYNAPSE" (Synchrotrons for Neuroscience: an Scientific Enterprise). They use x-ray imaging to attack coordinated fashion one of the issues modern science: structure animal and human brains, including neurons connections. The objective is develop Google-like maps also detailed structural functional information selected regions interest. sheer mass data needed poses...
An x-ray microtomography method combined with hard imaging microscopy was developed that has a potential spatial resolution of the order 10–100 nm. The system consists high-brilliance undulator source SPring-8, beam diffuser plate to reduce coherence illumination, high-precision rotating sample stage, Fresnel zone objective, and high-resolution detector. three-dimensional images several samples were observed successfully reconstructed pitch pattern 0.6 μm.
A hard X-ray focusing test of a Fresnel zone plate has been performed with synchrotron radiation source at the undulator beamline 20XU SPring-8. radius 150 µm, and an outermost width 100 nm was used for device. The 248-m-long provides fully coherent illumination focused beam evaluated by knife-edge-scan method scanning microscope using charts. Nearly diffraction-limited size 120 achieved first-order diffraction 10 keV X-ray. Evaluation third-order also 8 X-ray, focal 50 obtained.
Microfocusing of 100 keV x ray with a sputtered-sliced Fresnel zone plate (ss-FZP) has been performed at the 250-m-long beamline (20XU) SPring-8. The ss-FZP an outermost width 0.16 μm which is composed 70 layers alternating Cu and Al having thickness ∼180 was fabricated characterized. minimum focal spot size attained for first order beam 0.5 distance 900 mm photon energy keV. total flux microprobe ∼2×106 photons s−1 μm−2.
A Zernike-type phase-contrast X-ray microscope with a zone plate and phase was constructed at the Photon Factory BL3C2. Parallel monochromatic X-rays of 8.97 keV were incident on specimen direct beam transmitted through focused back focal plane plate, where an aluminium placed. Tantalum line patterns as fine 0.3 microm could be imaged. Phase-contrast images polypropylene wires polystyrene latex beads obtained, which showed better contrast than that their bright field images.
In this study, we designed and fabricated a multilayer Laue lens (MLL) as hard X-ray focusing device. MoSi2 Si were chosen to form the layers by DC magnetron sputtering owing their superior properties. The optical properties of MLL measured at BL24XU SPring-8 for 20-keV X-rays. order confirm effect dynamical diffraction, far-field diffraction images captured various incidence angles depths. resultant intensity distributions showed similar structure those derived through calculations. An...
A new total-reflection zone plate that consists of a reflective pattern with varied-space on flat substrate was fabricated for hard X-ray nanofocusing. This device is much easier to fabricate than other focusing devices. because its size smaller finest constituent structure since it exploits the effect glancing X-rays by having small total reflection angle. Its properties were evaluated using 10-keV and 14.4 nm achieved.
In conventional grating-based X-ray interferometry, it is necessary to repeatedly translate one of the gratings with high accuracy in regular submicron steps and ensure a constant dose delivery during each step. However, stepping errors fluctuations inevitably occur due mechanical inaccuracies and/or thermal drift interferometer process. As result these fluctuations, standard reconstruction procedure without considering them causes artifacts images as stripes specific frequencies. this...
Hard X-ray microbeam experiments with sputtered-sliced Fresnel zone plates have been performed. Zone an outermost width of 0.25 microm (#FZP1) and 0.1 (#FZP2) were fabricated evaluated. In a scanning microscopy experiment, line-and-space pattern structure as fine was resolved using #FZP2 at wavelength 1 A. As application the technique, two-dimensional distribution constituent elements in forensic samples has obtained (e.g. section view human elephant hairs) fluorescent microscopy.
A Zernike-type imaging microscope using a sputtered-sliced Fresnel zone plate (SS-FZP) has been developed and tested at an X-ray energy of 25 keV. The SS-FZP was used as objective. copper (Cu) phase placed the back focal plane in order to produce contrast. performance with gold (Au) mesh resolution test pattern undulator beamline 47 SPring-8. Au could be imaged transmission magnification x10.2. Owing Cu plate, different image contrast observed compared bright-field Tantalum microstructures...
A multilayer Laue lens (MLL) made from MoSi2/Si has been fabricated aiming at a sub‐10‐nm spatial resolution for hard x‐ray microscopy. of 1000 alternating MoSi2 and Si layers with layer thickness gradually increasing 5 nm to 316 according the Fresnel structure was deposited on silicon substrate using DC magnetron sputtering, then diced, polished thinned. The total about 10 μm. Optical properties were measured SPring‐8 beamline BL24XU 20‐keV x‐rays. While observing changes in far‐field...
The cotyledon of legume seeds is a storage organ that provides nutrients for seed germination and seedling growth. spatial temporal control the degradation processes within cotyledons has not been elucidated. Calcium oxalate (CaOx) crystals, common calcium deposit in plants, have often reported to be present seeds. In this study, micro-computed tomography (micro-CT) was employed at SPring-8 facility examine three-dimensional distribution crystals inside during maturation Lotus miyakojimae...
Abstract Four-dimensional phase computed tomography (4D CT) by an X-ray Talbot interferometer (XTI) with white synchrotron radiation has ever been demonstrated at a temporal resolution of about 1 s for soft-matter samples. However, the damage to samples caused occasionally hampers our understanding sample dynamical properties. Based on fact that XTI functions X-rays bandwidth up ca. 10% performance comparable monochromatic X-rays, filtering generate ‘pink-beam’ is effective reduce without...
A hard X-ray microbeam with zone plate optics has been tested, and preliminary experiments on scanning microscopy have performed. Fresnel fabricated by the electron-beam lithography technique is used as an focusing device. The material of structure tantalum thickness about 1 µm, outermost width 0.25 µm. focused spot size measured knife-edge 0.3 µm at energy 8 keV. Closer evaluation spatial resolution done observing test patterns in a experiment, fine 0.2 µm-structure resolved.
Hard X-ray microscopy with high spatial resolution (<or=0.1 microm) using a high-energy and high-brilliance microprobe is expected to be promising technology for various types of analysis, imaging etc. in materials science, biology medicine. A multilayer Fresnel zone plate (FZP) could approach focusing optics the region (>or=20 keV) because large thickness (aspect ratio) can available. Various FZPs have been fabricated by DC sputtering deposition. Their characteristics evaluated at undulator...
A hard X-ray nano-interferometer using two types of zone plate has been developed. One is an ordinary for a microscope objective, and the other newly designed called "annular plate" configuring reference waves. We have succeeded in producing interference fringes with variable periods up to fringeless pattern. The phase-shift distribution polystyrene microparticles could be imaged clearly spatial resolution 60 nm phase sensitivity λ/40 at photon energy 8 keV. Furthermore, this interferometer...
Microfocusing optics with total reflection mirrors has been constructed, and a performance test in the hard x-ray region carried out. The material of mirror is fused quartz, parabolic surface figures are fabricated by bent-polishing method. reflective coated platinum. By configuring two Kirkpatrick-Baez optics, focused beam size 150nm vertical direction ×110nm horizontal achieved at an energy 12keV. A smaller than 300nm obtained within range 8–28keV. In scanning microscope, fine periodic...
We have developed a four-dimensional (4D) x-ray microcomputed tomography (CT) system that can obtain time-lapse CT volumes in real time. The consists of high-speed sample rotation and high-frame-rate imager, which are installed at synchrotron radiation beamline. As result optimization introduction "zoom resolution" procedure, real-time 4D movie with frame rate 30 was obtained voxel size 2.5 μm using 10 keV x-rays.
A grating interferometer (GI) system has been installed in an X-ray microscope equipped with a Zernike phase contrast (ZPC) and Cu rotating anode source. The GI ZPC systems are switchable, their performances of information extraction have compared. is based on Lau consisting absorption π/2 grating, which extracts magnified shift map sample via phase-stepping measurement. generates image by using plate corresponding condenser device. the compared terms detectability objects. By Fourier...