- Obesity, Physical Activity, Diet
- Musculoskeletal pain and rehabilitation
- Statistical Methods in Clinical Trials
- Global Cancer Incidence and Screening
- Urban Transport and Accessibility
- Blood Pressure and Hypertension Studies
- Health disparities and outcomes
- Advanced Causal Inference Techniques
- Complementary and Alternative Medicine Studies
- Health Systems, Economic Evaluations, Quality of Life
- Bariatric Surgery and Outcomes
- Obesity and Health Practices
- Nutritional Studies and Diet
- Data-Driven Disease Surveillance
- Body Contouring and Surgery
- Statistical Methods and Bayesian Inference
- Radiology practices and education
- Physical Activity and Health
- Mindfulness and Compassion Interventions
- Pharmaceutical Practices and Patient Outcomes
- Spatial and Panel Data Analysis
- Acupuncture Treatment Research Studies
- Colorectal Cancer Screening and Detection
- Pharmacovigilance and Adverse Drug Reactions
- Heart Rate Variability and Autonomic Control
Kaiser Permanente Washington Health Research Institute
2016-2025
University of Washington
2015-2025
Seattle University
2008-2023
Kaiser Permanente
2010-2020
Credo Reference (United States)
2018
Justus-Liebig-Universität Gießen
2017
Group Health Cooperative
2007-2016
Cancer Research And Biostatistics
2009-2016
Ball State University
2014
Cornell University
2014
<h3>Context</h3>Treating hypertension decreases mortality and disability from cardiovascular disease, but most remains inadequately controlled.<h3>Objective</h3>To determine if a new model of care that uses patient Web services, home blood pressure (BP) monitoring, pharmacist-assisted improves BP control.<h3>Design, Setting, Participants</h3>A 3-group randomized controlled trial, the Electronic Communications Home Blood Pressure Monitoring study was based on Chronic Care Model. The trial...
<h3>Importance</h3> Mindfulness-based stress reduction (MBSR) has not been rigorously evaluated for young and middle-aged adults with chronic low back pain. <h3>Objective</h3> To evaluate the effectiveness pain of MBSR vs cognitive behavioral therapy (CBT) or usual care. <h3>Design, Setting, Participants</h3> Randomized, interviewer-blind, clinical trial in an integrated health care system Washington State 342 aged 20 to 70 years enrolled between September 2012 April 2014 randomly assigned...
Background: There has been a dramatic shift in use of bariatric procedures, but little is known about their long-term comparative effectiveness. Objective: To compare weight loss and safety among procedures. Design: Retrospective observational cohort study, January 2005 to September 2015. (ClinicalTrials.gov: NCT02741674) Setting: 41 health systems the National Patient-Centered Clinical Research Network. Participants: 65 093 patients aged 20 79 years with body mass index (BMI) 35 kg/m2 or...
Cognitive behavioral therapy (CBT) is believed to improve chronic pain problems by decreasing patient catastrophizing and increasing self-efficacy for managing pain. Mindfulness-based stress reduction (MBSR) benefit patients with mindfulness acceptance. However, little known about how these therapeutic mechanism variables relate each other or whether they are differentially impacted MBSR vs CBT. In a randomized controlled trial comparing MBSR, CBT, usual care (UC) adults aged 20 70 years low...
Bariatric surgery can lead to substantial improvements in type 2 diabetes (T2DM), but outcomes vary across procedures and populations. It is unclear which bariatric procedure has the most benefits for patients with T2DM.To evaluate associations of T2DM outcomes.This cohort study was conducted 34 US health system sites National Patient-Centered Clinical Research Network Study. Adult who had between January 1, 2005, September 30, 2015, were included. Data analysis from April 2017 August...
Purpose We determined whether the association between breast density and cancer risk severity differs according to menopausal status postmenopausal hormone therapy (HT) use. Methods collected data on 587,369 women who underwent 1,349,027 screening mammography examinations; 14,090 were diagnosed with cancer. calculated 5-year from a survival model for subgroups of classified by their Breast Imaging Reporting Data System (BIRADS) density, age, status, current HT use, assuming body mass index...
Objectives. We examined whether supermarket choice, conceptualized as a proxy for underlying personal factors, would better predict access to supermarkets and fruit vegetable consumption than mere physical proximity. Methods. The Seattle Obesity Study geocoded respondents’ home addresses locations of their primary supermarkets. Primary were stratified into low, medium, high cost according the market basket 100 foods. Data on obtained during telephone surveys. Linear regressions associations...
Background: Few studies have evaluated the effectiveness of massage for chronic low back pain. Objective: To compare 2 types and usual care Design: Parallel-group randomized, controlled trial. Randomization was computer-generated, with centralized allocation concealment. Participants were blinded to type but not assignment versus care. Massage therapists unblinded. The study personnel who assessed outcomes treatment assignment. (ClinicalTrials.gov registration number: NCT00371384) Setting:...
Additional data comparing longer-term problems associated with various bariatric surgical procedures are needed for shared decision-making.To compare the risks of intervention, operation, endoscopy, hospitalization, and mortality up to 5 years after 2 procedures.Adults who underwent Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG) between January 1, 2005, September 30, 2015, within National Patient-Centered Clinical Research Network. Data from 33 560 adults at 10 centers 4 clinical...
<h2>Abstract</h2><h3>Background</h3> Bariatric surgery has been used for treatment of severe obesity in adolescents but most studies have small and limited follow-up. <h3>Objectives</h3> We hypothesized that electronic health record data could be to compare effectiveness bariatric procedures adolescents. <h3>Setting</h3> Data were obtained from clinical research networks using a common model extract each site. <h3>Methods</h3> Adolescents who underwent primary procedure 2005 through 2015...
Summary While numerous methods have been proposed to test for spatial cluster detection, in particular discrete outcome data (e.g., disease incidence), few available continuous that are subject censoring. This article provides an extension of the scan statistic ( Kulldorff, 1997 , Communications Statistics 26, 1481–1496) censored and further proposes a simple detection method by utilizing cumulative martingale residuals within framework Cox's proportional hazards models. Simulations...
Although yoga is an effective treatment for chronic low back pain, little known about the mechanisms responsible its benefits. In a trial comparing to intensive stretching and self-care, we explored whether physical (hours of exercise/week), cognitive (fear avoidance, body awareness, self-efficacy), affective (psychological distress, perceived stress, positive states mind, sleep), physiological factors (cortisol, DHEA) mediated effects or on back-related dysfunction (Roland-Morris Disability...
Shopping at low-cost supermarkets has been associated with higher obesity rates. This study examined whether attitudes toward healthy eating are independently diet quality among shoppers low-cost, medium-cost, and high-cost supermarkets. Data on socioeconomic status (SES), eating, supermarket choice were collected using a telephone survey of representative sample adult residents King County, WA. Dietary intake data based food frequency questionnaire. Thirteen chains stratified into three...
Pragmatic clinical trials embedded within health care systems provide an important opportunity to evaluate new interventions and treatments. Networks have recently been developed support practical efficient studies. will lead improvements in how we deliver promise more rapidly translate research findings into practice.The National Institutes of Health (NIH) Care Systems Collaboratory was formed conduct pragmatic cultivate collaboration across areas disciplines develop best practices for...
Methodological advancements in epidemiology, biostatistics, and data science have strengthened the research world's ability to use captured from electronic health records (EHRs) address pressing medical questions, but gaps remain. We describe methods investments that are needed curate EHR toward quality integrate complementary sources when alone insufficient for goals. highlight new directions improving integrity of evidence generated pragmatic trials, observational studies, predictive...
Abstract Spatial cluster detection has become an important methodology in quantifying the effect of hazardous exposures. Previous methods have focused on cross‐sectional outcomes that are binary or continuous. There virtually no spatial proposed for longitudinal outcomes. This paper proposes a new method repeated using cumulative geographic residuals. A major advantage this is its ability to readily incorporate information study participants relocation, which most statistics cannot....
Background: Patient-shared electronic health records provide opportunities for care outside of office visits. However, those who might benefit may be unable to or choose not use these resources, while others need them. Objective: Electronic Communications and Home Blood Pressure Monitoring (e-BP) was a randomized trial that demonstrated Web-based pharmacist led improved blood pressure (BP) control. During recruitment we attempted contact all patients with hypertension from 10 clinics...