Karen Lee

ORCID: 0000-0002-6860-7509
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Research on Leishmaniasis Studies
  • Reproductive Biology and Fertility
  • Clinical practice guidelines implementation
  • Trypanosoma species research and implications
  • Ocular Surface and Contact Lens
  • Innovations in Medical Education
  • Delphi Technique in Research
  • Diversity and Career in Medicine
  • Health Literacy and Information Accessibility
  • Immune Cell Function and Interaction
  • Pluripotent Stem Cells Research
  • Telemedicine and Telehealth Implementation
  • Mobile Health and mHealth Applications
  • Injury Epidemiology and Prevention
  • Diverse Approaches in Healthcare and Education Studies
  • Assisted Reproductive Technology and Twin Pregnancy
  • Bipolar Disorder and Treatment
  • Organic Chemistry Cycloaddition Reactions
  • Photochromic and Fluorescence Chemistry
  • Mesenchymal stem cell research
  • Social Media in Health Education
  • Corneal Surgery and Treatments
  • Rabies epidemiology and control
  • Dental Health and Care Utilization
  • Economic and Financial Impacts of Cancer

King's College School
2024

King's College London
2024

University of Houston
2018-2021

Western University
2021

Princess Margaret Cancer Centre
2019

Faculty of Public Health
2017

California Animal Hospital
2015

Western University of Health Sciences
2015

Hong Kong Footwear Federation
2003

Yale University
2000

We show here that maintenance of Leishmania infections with mexicana complex parasites (Leishmania amazonensis and pifanoi) is impaired in the absence circulating antibody. In these studies, we used mice genetically altered to contain no antibody, without functional B cells. This experimental design allowed us rule out a critical role for cell antigen presentation pathogenesis. addition, lacking common gamma chain Fc receptors (FcgammaRI, FcepsilonRI, FcgammaRIII) are similarly refractory...

10.1084/jem.191.6.1063 article EN The Journal of Experimental Medicine 2000-03-20

Delivery of foreign antigens to mucosal surfaces, such as the pulmonary airways, has been shown preferentially induce Th2-mediated responses in humans and mice. What is not clear from these studies whether this preferential skewing result limited types antigen being administered / or a bias towards using particular genetic strains mice, lung environment itself provides favored site for priming Th2-type cells. We have addressed issue an mouse strain combination that, under typical conditions...

10.1002/1521-4141(200003)30:3<840::aid-immu840>3.0.co;2-l article EN European Journal of Immunology 2000-03-01

Background After a prostate cancer diagnosis, men want information about their disease and treatment options. The internet offers convenient means to deliver health patients with cancer. However, there are concerns the use of among this largely senior population. Objective This study aimed determine patterns factors associated as source Canadian features required in website. Methods Population surveys were conducted four provinces (British Columbia, Alberta, Saskatchewan, Ontario) 2014-2015....

10.2196/14241 article EN cc-by Journal of Medical Internet Research 2019-08-18

The Prevention of Adult Caries Study, an NIDCR-funded multicenter, double-blind, randomized clinical trial, enrolled 983 adults (aged 18-80 yrs) at high risk for developing caries (20 or more intact teeth and 2 lesions screening) to test the efficacy a chlorhexidine diacetate 10% weight per volume (w/v) dental coating (CHX). We excluded participants whom study treatment was contraindicated whose health might affect outcomes ability complete study. Participants were randomly assigned receive...

10.1177/0022034511424154 article EN Journal of Dental Research 2011-12-07

Exposure to surgery during medical school is limited. We ran a mentorship scheme pairing students at with local surgeons improve undergraduate insight. evaluated the effectiveness of in increasing surgical exposure and drivers for seeking mentorship.

10.1186/s12909-024-06047-0 article EN cc-by BMC Medical Education 2024-10-10

Objective: To present a tool that allows estimation of the budget impact treatments for acute mania in bipolar I disorder from US healthcare payer perspective.Methods: Using discrete event simulation, course individuals is simulated beginning with hospitalization. Discharge depends on symptom level measured by Young Mania Rating Scale (YMRS). The treatment effect determined using time-dependent regression equations derived trial data, and decision rules obtained clinical experts. Outcomes...

10.1185/030079906x148265 article EN Current Medical Research and Opinion 2006-10-10

Among the challenges in health research is translating interventions from controlled experimental settings to clinical and community where chronic disease managed daily. Pragmatic trials offer a method for testing real-world but are seldom used OA research. The aim of this study was evaluate literature on pragmatic up August 2016 order identify strengths weaknesses design reporting these trials. We established guidelines assess degree which 61 studies complied with trial reporting. assessed...

10.1093/rheumatology/kex050 article EN Lara D. Veeken 2017-02-21

The objectives of this study were to identify contextual factors as barriers or facilitators osteoarthritis management in urban- and rural-dwelling seniors by applying the World Health Organization's International Classification Functioning, Disability (ICF).Secondary analysis was performed on interview transcripts from (n ​= ​11) ​9) living with Canada. Meaningful concepts linked ICF codes (Environmental Factors) according established linking rules. Unclassified content (including Personal...

10.1016/j.ocarto.2020.100132 article EN cc-by-nc-nd Osteoarthritis and Cartilage Open 2021-01-18

Three cats with suspected Fournier's gangrene had an acute onset of clinical signs and bloodwork changes consistent sepsis. All cases similar progression wounds that were managed without aggressive surgical debridement, which is the currently accepted treatment choice. survived have maintained excellent long-term quality life.Fournier's a potentially fatal disease, few reported in veterinary literature. This retrospective case series describes only known reports survival from cats, none...

10.1177/2055116915589837 article EN cc-by-nc Journal of Feline Medicine and Surgery Open Reports 2015-01-01

<title>Abstract</title> Background Exposure to surgery during medical school is limited (1, 2). We ran a mentorship scheme pairing students at with local surgeons improve undergraduate insight. evaluated the effectiveness of in increasing surgical exposure and drivers for seeking mentorship. Methods 35 across 7 specialties were recruited matched 37 years 2–4 months. Quantitative qualitative evaluation was done pre-, mid- post-scheme questionnaires. Students rated confidence pursuing career...

10.21203/rs.3.rs-4263137/v1 preprint EN cc-by Research Square (Research Square) 2024-04-18

Delivery of foreign antigens to mucosal surfaces, such as the pulmonary airways, has been shown preferentially induce Th2-mediated responses in humans and mice. What is not clear from these studies whether this preferential skewing result limited types antigen being administered / or a bias towards using particular genetic strains mice, lung environment itself provides favored site for priming Th2-type cells. We have addressed issue an mouse strain combination that, under typical conditions...

10.1002/1521-4141(200003)30:3<840::aid-immu840>3.3.co;2-c article EN European Journal of Immunology 2000-03-01

<sec> <title>BACKGROUND</title> After a prostate cancer diagnosis, men want information about their disease and treatment options. The internet offers convenient means to deliver health patients with cancer. However, there are concerns the use of among this largely senior population. </sec> <title>OBJECTIVE</title> This study aimed determine patterns factors associated as source Canadian features required in website. <title>METHODS</title> Population surveys were conducted four provinces...

10.2196/preprints.14241 preprint EN 2019-04-02

LANGUAGE NOTE | Document text in English; abstract also Chinese.This paper outlines a brief history of the FESPIC (Far East &amp; South Pacific) Games and Hong Kong's involvement since 1975. It does not only present comprehensive report on preparation, participation achievement Kong, China Delegation 8th Busan Games, but skeletons important facets writing overseas competition. "Ecstasy agony" delegation are highlighted with conclusion recommendations for reference future...

10.24112/ajper.91285 article EN cc-by Asian Journal of Physical Education & Recreation 2003-12-01

10.1007/s11906-002-0019-0 article CA Current Hypertension Reports 2002-11-01
Coming Soon ...