Gerd Wübbeler

ORCID: 0000-0002-6871-8903
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About
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Research Areas
  • Scientific Measurement and Uncertainty Evaluation
  • Advanced Statistical Process Monitoring
  • EEG and Brain-Computer Interfaces
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Blind Source Separation Techniques
  • Advanced Sensor Technologies Research
  • Sparse and Compressive Sensing Techniques
  • Calibration and Measurement Techniques
  • Photoacoustic and Ultrasonic Imaging
  • Neural dynamics and brain function
  • Near-Field Optical Microscopy
  • Advanced MRI Techniques and Applications
  • Optical Imaging and Spectroscopy Techniques
  • Sensor Technology and Measurement Systems
  • Functional Brain Connectivity Studies
  • Bayesian Methods and Mixture Models
  • Advanced Condensed Matter Physics
  • Spectroscopy and Chemometric Analyses
  • Probabilistic and Robust Engineering Design
  • Physics of Superconductivity and Magnetism
  • Advanced Measurement and Metrology Techniques
  • Microwave and Dielectric Measurement Techniques
  • Fault Detection and Control Systems
  • Electromagnetic Fields and Biological Effects
  • Advanced Statistical Methods and Models

Physikalisch-Technische Bundesanstalt
2016-2025

Polish Botanical Society
2023

Charité - Universitätsmedizin Berlin
2003-2004

Franklin University
2001-2003

Berlin Heart (Germany)
2001

Freie Universität Berlin
1999-2000

Osnabrück University
1992-1996

The Guide to the Expression of Uncertainty in Measurement (GUM) is de facto standard for evaluation measurement uncertainty metrology. Recently, has been proposed on basis probability density functions (PDFs) using a Monte Carlo method. relation between this PDF approach and method described GUM outlined. required numerical calculation illustrated by its application two examples. results obtained examples are compared corresponding when applying GUM.

10.1088/0957-0233/19/8/084009 article EN Measurement Science and Technology 2008-07-04

Abstract Purpose To propose and illustrate a safety concept for multichannel transmit coils in MRI based on finite‐differences time‐domain (FDTD) simulations validated by measurements. Materials Methods FDTD of specific absorption rate (SAR) distributions cylindrical agarose phantom were carried out various radio frequency (RF) driving conditions four‐element coil array. Additionally, maps amplitude, signal phase, temperature rise following RF heating measured MRI. Results Quantitative...

10.1002/jmri.21149 article EN Journal of Magnetic Resonance Imaging 2007-10-29

Abstract The applications of virtual metrology and the concept using experiments (VEs) or digital twins in measurement tasks have gained significant interest recent years. When real measurements are costly scarce, a VE can replicate complex mathematical physical models. As representation process, can, among other use-cases, be used an uncertainty evaluation. Here, simulated observations combined without explicit knowledge model for measurand – usual requirement evaluation according to GUM...

10.1515/teme-2024-0110 article EN tm - Technisches Messen 2025-03-17

We apply a recently developed multivariate statistical data analysis technique-so called blind source separation (BSS) by independent component analysis-to process magnetoencephalogram recordings of near-DC fields. The extraction fields from MEG has great relevance for medical applications since slowly varying DC-phenomena have been found, e.g., in cerebral anoxia and spreading depression animals. Comparing several BSS approaches, it turns out that an algorithm based on temporal...

10.1109/10.841331 article EN IEEE Transactions on Biomedical Engineering 2000-05-01

Bandpass correction in spectrometer measurements using monochromators is often necessary order to obtain accurate measurement results. The classical approach of bandpass based on local polynomial approximations and the use finite differences. Here we compare this with an extension Richardson–Lucy method, which well known image processing, but has not been applied spectrum yet. Using extensive simulation study a practical example, demonstrate potential method. In contrast approach, it robust...

10.1088/0026-1394/50/2/107 article EN Metrologia 2013-02-08

A method for the simultaneous correction of bandpass and stray-light effects in array spectroradiometer data is presented. The based on inversion instrument matrix a device determined with help tuneable lasers. By applying Tikhonov regularization technique, straightforward measurement results possible.

10.1088/0026-1394/49/2/s43 article EN Metrologia 2012-03-02

Adaptive Monte Carlo schemes can be used to determine the number of trials (the evaluations measurement model) necessary for evaluation uncertainty according Supplement 1 GUM (GUM S1). The goal is reach a prescribed numerical accuracy results estimate, associated standard and coverage interval endpoints) chosen confidence level. It shown that simple sequential adaptive may not perform well in this regard an alternative method based on two-stage procedure due Stein proposed. implementation...

10.1088/0026-1394/47/3/023 article EN Metrologia 2010-05-04

Infrared scattering scanning near-field optical microscopy (IR s-SNOM) provides for spectroscopic imaging with nanometer spatial resolution, yet full spatio-spectral is constrained by long measurement times.Here, we demonstrate the application of compressed sensing algorithms to achieve hyperspectral FTIR-based nano-imaging at an order magnitude faster speed same spectral content compared conventional approaches.At example spectroscopy a single vibrational resonance, discuss relationship...

10.1364/oe.26.018115 article EN cc-by Optics Express 2018-06-28

A virtual experiment simulates a real measurement process by means of numerical model. The model produces data whose properties reflect those the observed in experiment. In this work, we explore how results can be employed context uncertainty evaluation for corresponding was based on Guide to Expression Uncertainty Measurement (GUM), which defines de facto standard metrology. We show that, under specific assumptions about structure and variance data, experiments combination with Monte Carlo...

10.3390/metrology2010008 article EN cc-by Metrology 2022-03-01

To reduce physiological artifacts in magnetoencephalographic (MEG) and electroencephalographic recordings, a number of methods have been applied the past such as principal component analysis, signal-space projection, regression using secondary information, independent analysis. This method has become popular it does not constraints orthogonality between artifact signal or need for priori information. Applying time-delayed decorrelation algorithm to raw data from visual stimulation MEG...

10.1109/10.991162 article EN IEEE Transactions on Biomedical Engineering 2002-04-01

Abstract The paper gives a short overview of various methods optical mammography, emphasizing scanning time-domain mammography. results clinical study on mammography are reviewed, comprising 154 patients carrying total 102 carcinomas validated by histology. A visibility score attributed to each carcinoma as qualitative measure tumour detectability indicates acceptable sensitivity but poor specificity for discrimination between malignant and benign lesions. Likewise, multi-variate statistical...

10.2478/s11772-008-0004-5 article EN cc-by-nc-nd Opto-Electronics Review 2008-01-01

Regression is a common task in metrology and often applied to calibrate instruments, evaluate inter-laboratory comparisons or determine fundamental constants, for example. Yet, regression model cannot be uniquely formulated as measurement function, consequently the Guide Expression of Uncertainty Measurement (GUM) its supplements are not applicable directly. Bayesian inference, however, well suited tasks, has advantage accounting additional priori information, which typically robustifies...

10.1088/0026-1394/52/6/878 article EN Metrologia 2015-11-18

Virtual experiments are a digital representation of real measurement and play crucial role in modern sciences metrology. Beyond their common usage as modeling validation tool, virtual experiment may also be employed to perform parameter sensitivity analysis or carry out uncertainty evaluation. For the latter compliant with statistical principles metrological guidelines, procedure obtain an estimate corresponding requires careful consideration. We employ Monte Carlo sampling using that allows...

10.3390/metrology4040033 article EN cc-by Metrology 2024-10-01

Most functional brain imaging methods detect neuronal activations indirectly through the accompanying neurovascular response. Here, we demonstrate that a novel methodological approach, combination of DC-magnetoencephalography (DC-MEG) and near-infrared spectroscopy (NIRS), allows non-invasive assessment dynamics coupling in human brain: detecting directly slow processes (with time constants 30s), DC-MEG revealed, even unaveraged recordings, sustained at pericentral hand cortices...

10.1097/00001756-200401190-00013 article EN Neuroreport 2003-12-23

<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> A novel approach for the determination of complex residual error parameters a calibrated one-port vector network analyzer (VNA) is proposed. The method based on single-reflection measurement employing high-precision airline terminated by short. complex-valued directivity and source match are extracted over entire measured frequency range applying sophisticated data analysis scheme utilizing...

10.1109/tim.2009.2017170 article EN IEEE Transactions on Instrumentation and Measurement 2009-07-30

Regression is an important task in metrology and least-squares methods are often applied this context. Bayesian inference provides alternative that can take into account available prior knowledge. We illustrate similarities differences of the two approaches terms a particular nonlinear regression problem. The impact knowledge utilized depends on amount information contained data, by considering data sets with different signal-to-noise ratios relevance employed for results investigated. In...

10.1088/0026-1394/53/1/s10 article EN Metrologia 2015-12-16

Recently, results for the CO(2) R(12) line strength parameter have been reported, which differ significantly and are inconsistent with respect to quoted uncertainties. We investigate what extent this inconsistency might be caused by chosen data analysis methods. To end, we assess compare a parametric fitting procedure non-parametric approach. apply methods simulated measured spectra, specify conditions required safe application of two procedures. For our present data, corresponding satisfied...

10.1063/1.3662134 article EN The Journal of Chemical Physics 2011-11-28

Neuroimaging techniques, such as fMRI, PET and near-infrared spectroscopy, monitor task-related neuronal activations in the brain indirectly through associated neurovascular/metabolic responses. To assess primary directly, magnetoencephalography was combined here with a mechanical modulation of head-to-sensor position signal separation via independent component analysis. In all five subjects this approach allowed to time evolution DC fields (< 0.1 Hz) over left hemisphere related complex...

10.1097/00001756-200106130-00034 article EN Neuroreport 2001-06-01

A key requirement for the evaluation of measurement uncertainty in metrology is its transferability. This particularly relevant ensuring traceability through a chain measurements. The GUM [JCGM 100] requires that ' it should be possible to use directly evaluated one result as component evaluating another which first used'. implements transfer by applying variance propagation linear models or can well approximated linearization. GUM-S1 101] has been released broaden scope cover also...

10.1088/1681-7575/ab50d6 article EN Metrologia 2019-10-24

The Guide to the Expression of Uncertainty in Measurement (GUM) has led a harmonization uncertainty evaluation throughout metrology. simplicity its employed methodology fostered broad acceptance GUM among metrologists. However, this also compromises best practice and does not provide state-of-the-art data analysis. Specifically, metrologists often possess useful prior knowledge about measurand which cannot be accounted for by GUM. Bayesian evaluation, on other hand, takes as starting point....

10.1088/1681-7575/aba3b8 article EN Metrologia 2020-07-07

Near-field goniometric measurements are employed to determine the photometric characteristics of light sources, i.e., spatial and angular distribution emitted light. To this end, a complex measurement system consisting goniometer CCD-based imaging photometer is employed. In order gain insight into enable characterization whole setup, we propose apply computer model conduct virtual experiments. Within model, current state all parts experiment can be easily controlled. The reliability...

10.1364/ao.53.001481 article EN Applied Optics 2014-02-26
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