A5055473874- Spondyloarthritis Studies and Treatments
- Rheumatoid Arthritis Research and Therapies
- Psoriasis: Treatment and Pathogenesis
- Autoimmune and Inflammatory Disorders Research
- Systemic Sclerosis and Related Diseases
- Systemic Lupus Erythematosus Research
- Bone and Joint Diseases
- Musculoskeletal synovial abnormalities and treatments
- Monoclonal and Polyclonal Antibodies Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Inflammatory Myopathies and Dermatomyositis
- Sarcoma Diagnosis and Treatment
- Peripheral Neuropathies and Disorders
- Osteoarthritis Treatment and Mechanisms
- Musculoskeletal Disorders and Rehabilitation
- Biosimilars and Bioanalytical Methods
- Spine and Intervertebral Disc Pathology
- Ultrasound and Hyperthermia Applications
- Pain Mechanisms and Treatments
- Elbow and Forearm Trauma Treatment
- Temporomandibular Joint Disorders
- Skin Diseases and Diabetes
- Vasculitis and related conditions
- Orthopedic Surgery and Rehabilitation
- Tendon Structure and Treatment
Santa Maria Nuova Hospital
2024-2025
Nuovo Ospedale San Giovanni di Dio
2017-2024
Azienda Usl Toscana Centro
2018-2023
Azienda Sanitaria di Firenze
2016-2017
University of Florence
2005-2016
Azienda Ospedaliero-Universitaria Careggi
2013
University of Milano-Bicocca
2013
University of Tirana
2011
Objective. To assess skin elasticity in systemic sclerosis (SSc) by using a new imaging modality, ultrasound elastography (UE). Methods. Our study included 18 consecutive patients with SSc and 15 healthy controls. Modified Rodnan score, physical examination, assessment of organ involvement were performed. UE was carried out on the middle forearm fingers dominant arm. The echo signals recorded real time during freehand operations probe compression relaxation produced images representing...
Currently, assessment of dermal thickness in systemic sclerosis (SSc) is performed by palpation and using the modified Rodnan skin score (mRSS).To verify whether high frequency ultrasound (US) may be a reliable reproducible method to measure digital thickness.In 70 patients with SSc, was evaluated US 2 observers at different sites on second digit dominant limb determine interobserver variability. Patients controls were examined twice first observer for intraobserver divided into three...
Objective. To investigate the presence of lower limb entheseal abnormalities in IBD patients without clinical signs and symptoms SpA their correlation with variables. Methods. A total 81 [55 Crohn's disease (CD) 26 ulcerative colitis (UC), 43 females 38 males, mean age 41.3 (12.4) years, BMI 24 (2)] low active (12) inactive (67) were consecutively studied US (LOGIQ5 General Electric 10-MHz linear array transducer) entheses compared 40 healthy controls matched for sex, BMI. Quadriceps,...
Objective. To investigate the relationships among neuropathic pain (NP), catastrophizing (PC), and central sensitization (CS) in relation to functional status radiological damage patients with knee osteoarthritis (OA). Methods. This cross-sectional study included OA derived from an observational cohort. The Spearman correlation test was used analyze relationship between Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) PainDetect Questionnaire (PDQ), Central Sensitization...
Introduction: Sleep disturbance (SD) in the second half of night due to inflammatory pain was included 2009 ASAS classification criteria Spondyloarthritis (SpA), even though its definition is uncertain. Aim: We aimed investigate SD early-SpA (e-SpA) patients at T1 (2010-2013), comparing them long-term SpA (l-SpA) T2 (2023-2024) after least 10 years follow-up. Methods: At T1, e-SpA and l-SpA cases, SD, classified as "difficulty initiating sleep" (DIS), maintaining (DMS) "early awakening"...
Background: Lung ultrasound (LUS) is a tool of growing interest in Rheumatoid Arthritis (RA) oligo- symptomatic ILD to avoid. Objective: We aimed evaluate (i) the prevalence pleural (PLUS) and parenchymal (PAUS) abnormalities LUS RA population their possible correlation biomarkers; (ii) predictivity gender, smoking habits, previous infections (past COVID-19 tuberculosis), treatments; (iii) differences between sexes. Methods: collected data 155 (15 early 140 late) patients with mild...
Objective. To compare clinical and X-ray examinations with US findings of SI joints (SIJ) in early SpA patients. Methods. Twenty-three patients, diagnosed according to Assessment SpondyloArthritis international Society criteria, were investigated clinically [sacral sulcus tenderness, BASMI, BASFI, BASDAI, pain fatigue visual analogue scale (VAS), morning stiffness sleep disturbance], SIJ X-rays (New York score) My Lab70 7–10 MHz (Esaote, Genoa, Italy), evaluating the width capsule posterior...
The aim of this study was to investigate the correlation between human leukocyte antigen (HLA) haplotypes and development antidrug antibodies (ADAs) in a cohort patients with rheumatic diseases.We evaluated presence ADAs 248 inflammatory diseases after 6 months treatment anti-TNF drugs: 26 were treated infliximab (IFX; three rheumatoid arthritis [RA], 13 ankylosing spondylitis [AS], 10 psoriatic [PsA]); 83 adalimumab (ADA; 24 RA, 36 AS, 23 PsA); 88 etanercept (ETA; 35 27 32 certolizumab...
The potential role of the COVID-19 vaccine and infection to induce autoimmunity is currently underestimated despite literature emphasizing arthralgia as a common adverse event. We aimed study impact rheumatological complications post-COVID-19 (PC) (PCV), comparing undifferentiated arthritis (UA) Polymyalgia Rheumatica, Horton's Arteritis (PMR-HA) isolated UA with "connective-like" accompanying symptoms. retrospectively included 109 patients at least 6 months follow-up, analyzing serum...
(1) Background: Rheumatoid arthritis (RA) is a chronic inflammatory joint disease, primarily characterized by pain. A significant proportion of patients report symptoms suggestive neuropathic The objectives this study were to investigate the presence an increased cross-sectional area (CSA) palmar digital nerves ultrasound in with active synovitis metacarpophalangeal joints and identify potential predictors such increase. (2) Methods: An examination clinically most affected hand (from second...
The main objective was to determine the prevalence of anti-dense fine speckled (DFS70) antibodies in a stable population undifferentiated connective tissue disease (UCTD) better define their potential role.Immunological and clinical records 91 long-standing UCTD patients were studied. DFS pattern determined using IIF ANA test on HEp-2 cells anti-DFS70 tested by chemiluminescence assay DFS70 line immunoassay.Twelve (13.2%) serum samples positive for immunoassay. There no statistical...