A5101443034- Silk-based biomaterials and applications
- Osteoarthritis Treatment and Mechanisms
- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- Ion-surface interactions and analysis
- Periodontal Regeneration and Treatments
- Graphene and Nanomaterials Applications
- Distributed Control Multi-Agent Systems
- Protein Hydrolysis and Bioactive Peptides
- Corneal Surgery and Treatments
- Supramolecular Self-Assembly in Materials
- Bluetooth and Wireless Communication Technologies
- Nanoplatforms for cancer theranostics
- Wireless Sensor Networks for Data Analysis
- Big Data and Digital Economy
- Graph theory and applications
- Cellular Mechanics and Interactions
- Tendon Structure and Treatment
- Polydiacetylene-based materials and applications
- Ferroelectric and Piezoelectric Materials
- Age of Information Optimization
- Software-Defined Networks and 5G
- Ocular Surface and Contact Lens
- Carbon and Quantum Dots Applications
- RNA Interference and Gene Delivery
Jinling Institute of Technology
2025
Zhongda Hospital Southeast University
2025
Southeast University
2020-2024
Anhui University of Finance and Economics
2023
Southern University of Science and Technology
2022
Osteochondral defects (OCD) cannot be efficiently repaired due to the unique physical architecture and pathological microenvironment including enhanced oxidative stress inflammation. Conventional strategies, such as control of implant microstructure or introduction growth factors, have limited functions failing manage these complex environments. Here we developed a multifunctional silk-based hydrogel incorporated with metal-organic framework nanozymes (CuTA@SF) provide suitable for OCD...
Endogenous repair of osteochondral defect is usually limited by the insufficient number cells in early stage and incomplete cell differentiation later stage. The development drug delivery systems for sequential release pro-migratory pro-chondrogenic molecules to induce endogenous bone marrow-derived mesenchymal stem (BMSCs) recruitment chondrogenic highly desirable situ regeneration. In this study, a novel, all-silk-derived system was fabricated incorporating tunable drug-loaded silk fibroin...
Abstract Stiffness is an important physical property of biomaterials that determines stem cell fate. Guiding differentiation via stiffness modulation has been considered in tissue engineering. However, the mechanism by which material regulates into tendon lineage remains controversial. Increasing evidence demonstrates immune cells interact with implanted and regulate behaviors paracrine signaling; however, role this not clear. In study, polydimethylsiloxane (PDMS) substrates different...
Under the global impetus toward carbon peak and neutrality, large-scale renewable energy integration has become a key driver in transforming traditional power grids into new systems. Meanwhile, growing adoption of advanced artificial intelligence (AI) approaches, especially models, heavily relies on high-performance computing (HPC) resources, which pose significant sustainability challenges due to their consumption emissions. This study introduces newly developed emission model (CEM) that...
Osteoarthritis (OA) is a prevalent joint disease characterized by pain, disability, and loss of physical function, posing challenge to public health. However, molecular mechanisms OA pathogenesis have not been fully described. We report that tripartite motif containing 15 (TRIM15) regulator in chondrocyte senescence OA. Our study revealed heightened expression TRIM15 chondrocytes senescent cartilage from patients with aged wild-type mice. Using gain- loss-of-function studies, we found...
Abstract Corneal injury due to ocular trauma or infection is one of the most challenging vision impairing pathologies that exists. Many studies focus on pro‐inflammatory and pro‐angiogenic effects interleukin‐1 β (IL‐1 ) corneal wound healing. However, effect IL‐1 keratocyte phenotype repair, as well underlying mechanisms, not clear. This study reports, for first time, induces changes keratocytes in vitro, by significantly down‐regulating gene protein expression levels markers (Keratocan,...
The development of a biomimetic scaffold designed to provide native extracellular matrix (ECM)-like microenvironment is potential strategy for cartilage repair. ECM in articular structurally composed three different architectural zones, i.e., horizontally aligned, randomly arranged, and vertically aligned collagen fibers. However, the effects scaffolds with these ECM-like architectures on vivo regeneration are not clear. In this study, we aim systematically investigate compare their situ...
While using ferroelectric polarization to tune the functional properties of 2D materials has been extensively studied recently, effects on ferroelectricity and piezoelectricity ferroelectrics are much less explored. In this work, we report markedly enhanced piezoelectric graphene/Pb(Zr0.52Ti0.48)O3/SrRuO3 (GR/PZT/SRO) capacitors. Compared with conventional metal-electroded capacitors, GR/PZT/SRO capacitors exhibit more abrupt switching, larger switchable polarization, lower leakage current,...
With the continuous development of manufacturing technology micro/nano devices based on GaN, focused gallium ion beam has become a momentous method for machining complex GaN structures. Therefore, this study focuses characterization and simulation sputtering etched profile by Ga FIB substrate. First, experiments are carried out to analyze influence dose, dwelling time, scan area, results reflect that regularity substrate differs from Si substrate, especially in redeposition effect, milling...
Flexible electronic skin, as an important part of bionic technology, has a wide range applications in the fields wearable devices, intelligent robots, and prostheses. Graphene, two-dimensional material with excellent electrical conductivity, mechanical flexibility chemical stability, shows great potential flexible skin. This paper reviews recent advances skin based on graphene its composites, presenting unique physicochemical properties advantages sensor materials. discusses detail...
Recent efforts in the network function virtualization (NFV) field have targeted ameliorating end-to-end latency of service chains (SFCs) using (NF) composition. NF composition breaks into building blocks and decides appropriate combination for these blocks. However, two issues remain current methods: (1) In sequential scope, fine-grained function's block-level eliminates redundancy, but with drawback flexibility restriction. (2) vertical complete parallelism adds overhead packet copying...
By constructing a knowledge graph based on traditional medical intangible cultural heritage, comprehensive organization and storage of heritage can be achieved, thereby achieving the protection culture. Firstly, Python's web crawler technology was used to obtain relevant data it cleaned organized. Subsequently, using technology, thematic extraction, fusion, correlation analysis were performed construct centered medicine. In process graph, ontology modeling semantic network model represent...
In this paper, we consider online convex optimization (OCO) with time-varying loss and constraint functions. Specifically, the decision maker chooses sequential decisions based only on past information, meantime functions are revealed over time. We first develop a class of model-based augmented Lagrangian methods (MALM) for functional constrained OCO (without feedback delay). Under standard assumptions, establish sublinear regret violation MALM. Furthermore, extend MALM to deal delayed...
In focused ion beam (FIB) fabrication process, the scan method is seldom cared about. choice of can make a difference in microstructure. this paper, proximity effect that caused by strategy observed. order to control effect, model phenomenon needs be clarified. To end, study proposed numerical considering and dwell time. By catching transient profile new incident angle relating time gained, with which expected estimate size effect. reality, calculation results show good match experiments...